Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SA27298_RS09050 Genome accession   NZ_AP018548
Coordinates   1843456..1844727 (-) Length   423 a.a.
NCBI ID   WP_003031814.1    Uniprot ID   A0A448AJR5
Organism   Streptococcus anginosus strain CCUG 27928     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1838456..1849727
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS09015 (SA27298_1838) - 1839327..1839638 (-) 312 WP_003027765.1 DUF1292 domain-containing protein -
  SA27298_RS09020 (SA27298_1839) ruvX 1839656..1840075 (-) 420 WP_003031265.1 Holliday junction resolvase RuvX -
  SA27298_RS09025 (SA27298_1840) - 1840075..1840341 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  SA27298_RS09030 (SA27298_1841) - 1840465..1841022 (-) 558 WP_003026633.1 SP0191 family lipoprotein -
  SA27298_RS09035 (SA27298_1842) - 1841126..1841695 (-) 570 WP_018543617.1 SP0191 family lipoprotein -
  SA27298_RS09040 (SA27298_1843) spx 1841781..1842179 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  SA27298_RS09045 (SA27298_1844) recA 1842266..1843411 (-) 1146 WP_018543618.1 recombinase RecA Machinery gene
  SA27298_RS09050 (SA27298_1845) cinA 1843456..1844727 (-) 1272 WP_003031814.1 competence/damage-inducible protein A Machinery gene
  SA27298_RS09055 (SA27298_1847) - 1845327..1845740 (+) 414 WP_018543619.1 EamA family transporter -
  SA27298_RS09060 (SA27298_1848) - 1845843..1846421 (-) 579 WP_003031817.1 DNA-3-methyladenine glycosylase I -
  SA27298_RS09065 (SA27298_1849) ruvA 1846432..1847022 (-) 591 WP_003031812.1 Holliday junction branch migration protein RuvA -
  SA27298_RS09070 (SA27298_1850) - 1847093..1848028 (-) 936 WP_126438392.1 IS30 family transposase -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 45790.22 Da        Isoelectric Point: 6.0828

>NTDB_id=70011 SA27298_RS09050 WP_003031814.1 1843456..1844727(-) (cinA) [Streptococcus anginosus strain CCUG 27928]
MKAEIIAVGTEILTGQIVNTNARFLSEKLASLGVDVYFQTAVGDNEARLLSILEIARNRSNLVILTGGLGPTEDDLTKQT
LAKFLNRRLVFDRMATEKLDRFFASRPDYARTPNNERQAQIVEGSTPLQNETGLAIGGVIEVSGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGDLIDNQTDPTIAPYAKTGEVTLRLSTKAASQNEADTKFAHLEKKI
LAVQTFEKQHLADLFYAYGDDSSLGQTAFELLRRAGKTVTAAESLTAGLFQATLASFAGASNVFSGGFVTYSMEEKSRML
DIPLADLEKHGVVSAFTAEKMAEQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATTEDVQSIKVNSAGRSRTDVR
KIAVLHAFNLLRKTLLKNENMLQ

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=70011 SA27298_RS09050 WP_003031814.1 1843456..1844727(-) (cinA) [Streptococcus anginosus strain CCUG 27928]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAAATTCTGACAGGTCAGATTGTCAATACAAATGCCCGATTTTTATCGGA
AAAATTAGCGAGTCTGGGTGTAGATGTGTATTTCCAAACAGCGGTTGGAGATAATGAAGCTCGTCTGTTATCCATTTTAG
AAATTGCTCGAAATCGTAGTAATTTGGTCATCTTAACTGGAGGATTAGGCCCAACAGAAGATGACTTGACTAAGCAGACT
TTGGCAAAATTCTTAAATCGTAGGTTGGTATTTGACCGAATGGCTACGGAGAAATTGGACCGCTTTTTCGCAAGTCGACC
GGATTATGCTCGAACACCAAACAATGAGCGACAAGCTCAGATAGTGGAAGGCTCGACTCCTCTACAAAATGAAACTGGGC
TTGCAATAGGAGGCGTGATTGAAGTCAGTGGCGTGACTTATGTTGTTCTACCTGGTCCGCCTAGTGAATTAAAACCTATG
GTAAATAATGAGCTGGTTCCGCTGTTAGCAACTGGTCAAAAATTGTATTCAAGAGTCTTGCGATTCTTTGGTATCGGTGA
AAGTCAATTAGTAACCCTTTTAGGAGATTTAATTGATAATCAGACCGATCCAACCATTGCTCCTTATGCTAAGACGGGAG
AGGTGACATTGCGATTGTCCACCAAGGCTGCTAGTCAAAATGAAGCAGATACTAAGTTTGCTCATTTAGAAAAGAAAATT
TTGGCAGTACAGACTTTTGAGAAACAACATTTAGCTGATCTTTTCTACGCTTATGGAGATGATAGTTCTCTGGGACAAAC
AGCTTTTGAACTGCTGAGAAGAGCAGGAAAGACCGTCACAGCAGCTGAAAGTTTGACTGCAGGACTCTTTCAAGCAACTT
TGGCAAGCTTTGCTGGAGCCTCCAATGTCTTTAGTGGTGGCTTTGTTACCTACAGTATGGAGGAAAAGAGCCGAATGCTG
GACATTCCTTTGGCAGACTTGGAAAAACATGGGGTAGTTTCAGCTTTTACAGCTGAGAAAATGGCTGAGCAGGCAAGAAA
ATTGACCGCTAGTGACTATGCGGTGAGCTTGACAGGTGTGGCAGGTCCAGACAGCTTAGAAGGACATCCAGCAGGGACAG
TTTATATTGGCTTAGCAACTACAGAGGATGTTCAGTCTATTAAGGTTAATAGTGCGGGTCGTAGTCGGACAGATGTACGT
AAAATAGCCGTTCTGCATGCTTTCAATCTGCTGCGAAAAACTTTATTAAAAAACGAAAATATGCTACAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A448AJR5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

76.555

98.818

0.757
  cinA Streptococcus mitis NCTC 12261

75.598

98.818

0.747
  cinA Streptococcus pneumoniae TIGR4

75.12

98.818

0.742
  cinA Streptococcus pneumoniae Rx1

75.12

98.818

0.742
  cinA Streptococcus pneumoniae R6

75.12

98.818

0.742
  cinA Streptococcus pneumoniae D39

74.88

98.818

0.74
  cinA Streptococcus mutans UA159

71.631

100

0.716
  cinA Streptococcus suis isolate S10

55.288

98.345

0.544
  cinA Bacillus subtilis subsp. subtilis str. 168

45.455

98.818

0.449

Multiple sequence alignment