Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   SA27298_RS04250 Genome accession   NZ_AP018548
Coordinates   868077..868919 (+) Length   280 a.a.
NCBI ID   WP_003030240.1    Uniprot ID   A0AAN4T4Q9
Organism   Streptococcus anginosus strain CCUG 27928     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 863077..873919
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SA27298_RS04225 (SA27298_0867) - 863966..864883 (+) 918 WP_003030263.1 MBL fold metallo-hydrolase -
  SA27298_RS04230 (SA27298_0868) ylqF 865003..865854 (+) 852 WP_018543478.1 ribosome biogenesis GTPase YlqF -
  SA27298_RS04235 (SA27298_0869) - 865841..866623 (+) 783 WP_003030264.1 ribonuclease HII -
  SA27298_RS04240 (SA27298_0870) - 866620..867447 (+) 828 WP_003030277.1 PRD domain-containing protein -
  SA27298_RS04245 (SA27298_0871) - 867437..867994 (+) 558 WP_003030231.1 sugar O-acetyltransferase -
  SA27298_RS04250 (SA27298_0872) dprA/cilB/dalA 868077..868919 (+) 843 WP_003030240.1 DNA-processing protein DprA Machinery gene
  SA27298_RS04255 (SA27298_0873) topA 869005..871098 (+) 2094 WP_108720863.1 type I DNA topoisomerase -
  SA27298_RS04260 (SA27298_0874) - 871162..871659 (+) 498 WP_003030245.1 hypothetical protein -
  SA27298_RS04265 (SA27298_0875) trmFO 871833..873167 (+) 1335 WP_003030238.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -

Sequence

Protein


Download         Length: 280 a.a.        Molecular weight: 31118.60 Da        Isoelectric Point: 5.2196

>NTDB_id=69980 SA27298_RS04250 WP_003030240.1 868077..868919(+) (dprA/cilB/dalA) [Streptococcus anginosus strain CCUG 27928]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFSSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIIKELSNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYSSEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide


Download         Length: 843 bp        

>NTDB_id=69980 SA27298_RS04250 WP_003030240.1 868077..868919(+) (dprA/cilB/dalA) [Streptococcus anginosus strain CCUG 27928]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCTGGCTTGACCAATCAGCAGGTCATCAATGTTCTCTCGTATGCTGA
GATACAAGAAAAAGAATTATCGGTAAAAGATATGGCAGTTGTTTCGGAATGCCGTAATCCTGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGATGATTTATTACGTCAAGAATTTGAAAAGTTCTCATCCTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGCGAAATTTACAATCCGCCCGTTCTTCTTTTTTATAAAGGTAATTTGGATTTGCTAAAATTACCTAAAGT
AGCTGTTGTAGGAAGTCGGAATAGTAGCCGAGTAGGCAGTCAATCCGTTCAAAAGATTATTAAAGAGCTAAGCAATGAAT
TGGTTATCGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCATTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGTCTAGACGTTTTTTATCCAAGGGCGAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAATATAGTTCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GCAGAGGGGTTATTGTTGCTGAAGCCAAAATGCGCTCAGGAAGTTTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
TGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(71-269)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(1-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

76.071

100

0.761
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

75.714

100

0.757
  dprA/cilB/dalA Streptococcus pneumoniae D39

75.714

100

0.757
  dprA/cilB/dalA Streptococcus pneumoniae R6

75.714

100

0.757
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

75.714

100

0.757
  dprA/cilB/dalA Streptococcus mitis SK321

75.357

100

0.754
  dprA Streptococcus mutans UA159

65.357

100

0.654
  dprA Lactococcus lactis subsp. cremoris KW2

57.857

100

0.579
  dprA Staphylococcus aureus N315

38.298

100

0.386
  dprA Legionella pneumophila strain ERS1305867

44.813

86.071

0.386
  dprA Staphylococcus aureus MW2

38.078

100

0.382
  dprA Bacillus subtilis subsp. subtilis str. 168

44.934

81.071

0.364

Multiple sequence alignment