Detailed information    

insolico Bioinformatically predicted

Overview


Name   comYC   Type   Machinery gene
Locus tag   EP162_RS06335 Genome accession   NZ_AP018524
Coordinates   1469180..1469413 (-) Length   77 a.a.
NCBI ID   WP_013774257.1    Uniprot ID   F3YBE3
Organism   Melissococcus plutonius strain DAT585     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1466375..1504638 1469180..1469413 within 0


Gene organization within MGE regions


Location: 1466375..1504638
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP162_RS06310 (DAT585_1280) - 1466375..1467382 (-) 1008 WP_013774253.1 class I SAM-dependent methyltransferase -
  EP162_RS06315 (DAT585_1281) comGG 1467662..1468000 (-) 339 WP_268765908.1 competence type IV pilus minor pilin ComGG -
  EP162_RS06320 (DAT585_1282) comGF 1467997..1468437 (-) 441 WP_053078316.1 competence type IV pilus minor pilin ComGF -
  EP162_RS06325 (DAT585_1283) - 1468418..1468762 (-) 345 WP_041363232.1 hypothetical protein -
  EP162_RS06330 (DAT585_1284) comGD 1468779..1469183 (-) 405 WP_013774256.1 competence type IV pilus minor pilin ComGD -
  EP162_RS06335 (DAT585_1285) comYC 1469180..1469413 (-) 234 WP_013774257.1 competence type IV pilus major pilin ComGC Machinery gene
  EP162_RS06340 - 1469792..1470076 (-) 285 WP_041363488.1 hypothetical protein -
  EP162_RS06345 (DAT585_1287) - 1470066..1470665 (-) 600 WP_013774259.1 Panacea domain-containing protein -
  EP162_RS06350 (DAT585_1288) - 1471287..1472051 (-) 765 WP_268766437.1 peptidoglycan amidohydrolase family protein -
  EP162_RS06355 (DAT585_1289) - 1472057..1472251 (-) 195 WP_013774261.1 phage holin -
  EP162_RS06360 (DAT585_1290) - 1472253..1472495 (-) 243 WP_013774262.1 hemolysin XhlA family protein -
  EP162_RS06365 (DAT585_1291) - 1472533..1472679 (-) 147 WP_013774263.1 XkdX family protein -
  EP162_RS06370 (DAT585_1292) - 1472669..1473043 (-) 375 WP_013774264.1 hypothetical protein -
  EP162_RS06375 (DAT585_1293) - 1473063..1473524 (-) 462 WP_048590192.1 hypothetical protein -
  EP162_RS06380 (DAT585_1294) - 1473524..1474216 (-) 693 WP_013774265.1 phage baseplate upper protein -
  EP162_RS06385 (DAT585_1295) - 1474206..1474454 (-) 249 WP_013774266.1 hypothetical protein -
  EP162_RS06390 (DAT585_1296) - 1474454..1475830 (-) 1377 WP_048590191.1 phage tail protein -
  EP162_RS06395 (DAT585_1297) - 1475843..1476667 (-) 825 WP_013774268.1 phage tail family protein -
  EP162_RS06400 (DAT585_1298) - 1476667..1478523 (-) 1857 WP_158309120.1 transglycosylase SLT domain-containing protein -
  EP162_RS06405 (DAT585_1299) - 1479007..1480824 (-) 1818 WP_127468704.1 tape measure protein -
  EP162_RS06410 (DAT585_1300) - 1480945..1481562 (-) 618 Protein_1278 Gp15 family bacteriophage protein -
  EP162_RS06420 (DAT585_1302) - 1481698..1482000 (-) 303 WP_048594068.1 hypothetical protein -
  EP162_RS06430 (DAT585_1303) - 1482306..1482827 (-) 522 WP_013774273.1 phage tail tube protein -
  EP162_RS06435 (DAT585_1304) - 1482824..1483231 (-) 408 WP_048590187.1 phage tail terminator protein -
  EP162_RS06440 (DAT585_1305) - 1483231..1483584 (-) 354 WP_013774275.1 minor capsid protein -
  EP162_RS06445 (DAT585_1306) - 1483585..1483935 (-) 351 WP_013774276.1 putative minor capsid protein -
  EP162_RS09390 (DAT585_1307) - 1483932..1484135 (-) 204 WP_232038649.1 hypothetical protein -
  EP162_RS09395 (DAT585_1308) - 1484154..1484321 (-) 168 WP_013774278.1 hypothetical protein -
  EP162_RS06455 (DAT585_1309) - 1484388..1485251 (-) 864 WP_048590186.1 hypothetical protein -
  EP162_RS09710 - 1485263..1485841 (-) 579 Protein_1287 phage scaffolding protein -
  EP162_RS06470 (DAT585_1312) - 1485952..1487088 (-) 1137 Protein_1288 phage minor capsid protein -
  EP162_RS06475 (DAT585_1314) - 1487091..1488647 (-) 1557 WP_048590185.1 phage portal protein -
  EP162_RS06480 - 1488664..1489916 (-) 1253 Protein_1290 PBSX family phage terminase large subunit -
  EP162_RS06485 (DAT585_1318) - 1489982..1490491 (-) 510 WP_013774288.1 terminase small subunit -
  EP162_RS09775 - 1490727..1490813 (-) 87 WP_221293899.1 putative holin-like toxin -
  EP162_RS06490 (DAT585_1320) - 1491083..1491562 (-) 480 WP_145986062.1 hypothetical protein -
  EP162_RS06495 (DAT585_1321) - 1491936..1492355 (-) 420 WP_013774291.1 transcriptional regulator -
  EP162_RS06500 (DAT585_1322) - 1492369..1492635 (-) 267 WP_013774292.1 hypothetical protein -
  EP162_RS06505 (DAT585_1323) - 1492625..1493011 (-) 387 WP_013774293.1 hypothetical protein -
  EP162_RS06510 (DAT585_1324) - 1493012..1493212 (-) 201 WP_013774294.1 hypothetical protein -
  EP162_RS06515 (DAT585_1325) - 1493313..1494059 (-) 747 WP_013774295.1 hypothetical protein -
  EP162_RS06520 (DAT585_1326) - 1494066..1494485 (-) 420 WP_013774296.1 hypothetical protein -
  EP162_RS06525 (DAT585_1327) - 1494516..1494935 (-) 420 WP_013774297.1 RusA family crossover junction endodeoxyribonuclease -
  EP162_RS09780 (DAT585_1328) - 1494953..1495249 (-) 297 WP_013774298.1 single-stranded DNA-binding protein -
  EP162_RS09785 (DAT585_1329) ssb 1495276..1495458 (-) 183 WP_013774299.1 single-stranded DNA-binding protein Machinery gene
  EP162_RS06535 (DAT585_1330) - 1495455..1496015 (-) 561 WP_048590183.1 hypothetical protein -
  EP162_RS09790 (DAT585_1331) - 1496461..1496880 (-) 420 WP_414973931.1 phage replisome organizer N-terminal domain-containing protein -
  EP162_RS06545 (DAT585_1332) - 1496920..1497606 (-) 687 WP_013774302.1 putative HNHc nuclease -
  EP162_RS06550 (DAT585_1333) - 1497714..1498424 (-) 711 WP_231849634.1 PD-(D/E)XK nuclease-like domain-containing protein -
  EP162_RS06555 (DAT585_1334) bet 1498375..1499103 (-) 729 WP_013774304.1 phage recombination protein Bet -
  EP162_RS06560 (DAT585_1335) - 1499096..1499404 (-) 309 WP_013774305.1 hypothetical protein -
  EP162_RS09105 (DAT585_1336) - 1499459..1499599 (-) 141 WP_013774306.1 hypothetical protein -
  EP162_RS06565 (DAT585_1337) - 1499596..1499787 (-) 192 WP_013774307.1 hypothetical protein -
  EP162_RS06570 (DAT585_1338) - 1499774..1499953 (-) 180 WP_013774308.1 hypothetical protein -
  EP162_RS06575 (DAT585_1339) - 1499966..1500724 (-) 759 WP_013774309.1 phage repressor protein/antirepressor Ant -
  EP162_RS06580 (DAT585_1340) - 1500721..1500963 (-) 243 WP_013774310.1 helix-turn-helix transcriptional regulator -
  EP162_RS06585 (DAT585_1341) - 1501149..1501865 (+) 717 WP_041363490.1 XRE family transcriptional regulator -
  EP162_RS06590 (DAT585_1342) - 1501970..1502641 (+) 672 WP_053078312.1 hypothetical protein -
  EP162_RS06595 (DAT585_1343) - 1502739..1503083 (+) 345 WP_127468707.1 hypothetical protein -
  EP162_RS09795 - 1503203..1504638 (+) 1436 Protein_1317 recombinase family protein -

Sequence


Protein


Download         Length: 77 a.a.        Molecular weight: 8909.56 Da        Isoelectric Point: 6.3134

>NTDB_id=69855 EP162_RS06335 WP_013774257.1 1469180..1469413(-) (comYC) [Melissococcus plutonius strain DAT585]
MLIVLLILSVLILLFVPNLAKQKETIDQKGNEAIVKVIEAQMELYELDKNVKPSAEQLLTEKYITKDQYEKYQTAKK

Nucleotide


Download         Length: 234 bp        

>NTDB_id=69855 EP162_RS06335 WP_013774257.1 1469180..1469413(-) (comYC) [Melissococcus plutonius strain DAT585]
ATGCTCATTGTTTTGCTTATTCTTTCTGTTTTAATTTTGTTATTTGTTCCAAATCTAGCAAAACAAAAAGAAACAATTGA
TCAAAAAGGAAATGAAGCAATTGTTAAAGTTATTGAAGCACAAATGGAATTATATGAATTAGACAAAAATGTAAAACCTT
CTGCTGAACAATTATTAACGGAAAAATACATTACTAAAGATCAATATGAAAAATATCAAACAGCTAAAAAATGA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB F3YBE3

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus suis isolate S10

53.247

100

0.532

  comGC/cglC Streptococcus pneumoniae Rx1

54.795

94.805

0.519

  comGC/cglC Streptococcus pneumoniae D39

54.795

94.805

0.519

  comGC/cglC Streptococcus pneumoniae R6

54.795

94.805

0.519

  comGC/cglC Streptococcus pneumoniae TIGR4

54.795

94.805

0.519

  comYC Streptococcus gordonii str. Challis substr. CH1

53.333

97.403

0.519

  comGC Bacillus subtilis subsp. subtilis str. 168

44.118

88.312

0.39

  comGC/cglC Streptococcus mitis NCTC 12261

50.847

76.623

0.39

  comGC/cglC Streptococcus mitis SK321

50.847

76.623

0.39

  comGC Lactococcus lactis subsp. cremoris KW2

47.458

76.623

0.364


Multiple sequence alignment