Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EP162_RS01350 Genome accession   NZ_AP018524
Coordinates   303661..304905 (+) Length   414 a.a.
NCBI ID   WP_013773215.1    Uniprot ID   F3Y8E9
Organism   Melissococcus plutonius strain DAT585     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 298661..309905
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EP162_RS01340 (DAT585_0269) - 301283..302203 (+) 921 WP_013773213.1 peptidase U32 family protein -
  EP162_RS01345 (DAT585_0270) - 302219..303460 (+) 1242 WP_048589639.1 peptidase U32 family protein -
  EP162_RS01350 (DAT585_0271) cinA 303661..304905 (+) 1245 WP_013773215.1 competence/damage-inducible protein A Machinery gene
  EP162_RS01355 (DAT585_0272) recA 305020..306108 (+) 1089 WP_013773216.1 recombinase RecA Machinery gene
  EP162_RS01360 (DAT585_0273) rny 306476..308032 (+) 1557 WP_013773217.1 ribonuclease Y -
  EP162_RS01365 (DAT585_0274) - 308517..309296 (+) 780 WP_013773218.1 TIGR00282 family metallophosphoesterase -
  EP162_RS01370 (DAT585_0275) - 309445..309816 (+) 372 WP_013773219.1 RicAFT regulatory complex protein RicA family protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 46250.01 Da        Isoelectric Point: 6.6599

>NTDB_id=69833 EP162_RS01350 WP_013773215.1 303661..304905(+) (cinA) [Melissococcus plutonius strain DAT585]
MKAEIIAVGTEILLGQIVNTNATFLSEELASLGIEVYYQTVVGDNAQRLTQLLKIAQKRSDLIILCGGLGPTEDDLTKET
IANYLHKSLIEDQDGLRNLQHFFELSKRKMTKNNLRQILTIKDGYTLQNQTGLAVGTLIENDKTNYLLLPGPPNELQPMF
QQFARPLLEKLFPQREQLFSKVLRFYGIGESQLVTELKELIDQQTNPTIAPYAKTNEVTLRLTAKATDEKTSNKMLLSLE
KQIMEKVGSYFYGYGENNSLAKVVAHLLKEKQKTITAAESLTSGLFQSTLGEISGISQIFKGGFVVYTEETKENFLNIPK
ELLENDGTVSEICAIKMAEHARQLANTDYAISFTGVAEKTLEGKPAGTVWIGFSQKNQTAFARSFQFNGDRNSVRQHAVM
QGLALIRQIVLNKE

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=69833 EP162_RS01350 WP_013773215.1 303661..304905(+) (cinA) [Melissococcus plutonius strain DAT585]
ATGAAAGCAGAAATTATAGCAGTAGGAACAGAAATTTTACTCGGCCAAATAGTGAATACAAATGCAACCTTTTTATCAGA
GGAACTAGCTTCCTTAGGCATTGAGGTATATTACCAGACAGTTGTTGGTGACAATGCACAACGATTGACACAGCTTTTAA
AGATTGCACAAAAACGTAGCGATTTGATTATTCTATGTGGTGGATTAGGACCAACAGAAGATGATTTAACAAAAGAAACA
ATTGCAAACTATCTTCATAAATCTTTAATTGAAGATCAAGATGGACTAAGAAATCTCCAGCATTTTTTTGAACTGTCTAA
AAGAAAAATGACAAAGAATAATTTACGACAAATTTTGACAATTAAGGATGGTTATACATTACAAAATCAAACAGGGCTGG
CTGTAGGTACATTAATAGAGAATGATAAAACGAACTATTTATTATTGCCAGGACCACCAAATGAATTACAGCCAATGTTT
CAACAATTTGCTAGACCTCTATTGGAAAAGCTTTTTCCTCAAAGAGAACAACTATTTTCCAAAGTTTTACGTTTTTATGG
TATCGGGGAATCACAATTAGTTACAGAATTGAAGGAACTGATTGATCAGCAAACAAATCCGACCATTGCACCTTATGCAA
AAACAAATGAAGTAACCTTACGCTTGACTGCAAAGGCAACAGATGAAAAGACAAGTAATAAAATGCTGCTTTCATTAGAA
AAACAAATTATGGAAAAAGTTGGGAGTTACTTTTACGGTTATGGAGAAAATAATAGTTTAGCAAAGGTAGTTGCTCATTT
ATTAAAAGAAAAACAAAAAACAATAACAGCGGCTGAAAGTTTAACGTCAGGATTATTTCAAAGTACATTAGGTGAAATTA
GTGGTATATCTCAAATTTTTAAGGGTGGATTTGTTGTTTATACAGAAGAAACCAAAGAAAATTTTTTAAATATTCCCAAA
GAACTCTTGGAAAATGATGGAACAGTTAGTGAAATTTGTGCCATAAAAATGGCAGAACACGCACGTCAATTAGCAAATAC
TGATTATGCAATTTCATTTACAGGTGTAGCTGAGAAAACATTGGAAGGAAAACCTGCTGGAACAGTTTGGATTGGATTTT
CACAGAAAAACCAAACAGCATTTGCTAGGTCATTTCAGTTTAACGGTGATCGTAATAGTGTTCGTCAACATGCTGTTATG
CAAGGCTTAGCGCTTATTCGCCAGATAGTTTTAAATAAAGAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F3Y8E9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

54.808

100

0.551
  cinA Streptococcus mitis SK321

52.358

100

0.536
  cinA Streptococcus pneumoniae TIGR4

51.887

100

0.531
  cinA Streptococcus mitis NCTC 12261

51.651

100

0.529
  cinA Streptococcus pneumoniae D39

51.415

100

0.527
  cinA Streptococcus pneumoniae Rx1

51.415

100

0.527
  cinA Streptococcus pneumoniae R6

51.415

100

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

48.91

99.758

0.488
  cinA Streptococcus suis isolate S10

53.074

74.638

0.396

Multiple sequence alignment