Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SR187_RS00405 Genome accession   NZ_AP018400
Coordinates   66740..67921 (+) Length   393 a.a.
NCBI ID   WP_120171188.1    Uniprot ID   A0A2Z5TTG8
Organism   Streptococcus ruminantium strain GUT-187     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 61740..72921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SR187_RS00385 (SR187_0405) - 61884..63383 (+) 1500 WP_120171182.1 quinol oxidase -
  SR187_RS00390 (SR187_0410) mutL 63521..65458 (+) 1938 WP_120171184.1 DNA mismatch repair endonuclease MutL -
  SR187_RS00395 (SR187_0415) ruvA 65487..66077 (+) 591 WP_120171186.1 Holliday junction branch migration protein RuvA -
  SR187_RS00400 (SR187_0420) - 66127..66681 (+) 555 WP_024532323.1 DNA-3-methyladenine glycosylase I -
  SR187_RS00405 (SR187_0425) cinA 66740..67921 (+) 1182 WP_120171188.1 competence/damage-inducible protein A Machinery gene
  SR187_RS00410 (SR187_0430) recA 67973..69115 (+) 1143 WP_024532325.1 recombinase RecA Machinery gene
  SR187_RS00415 (SR187_0435) spx 69645..70043 (+) 399 WP_024532326.1 transcriptional regulator Spx -
  SR187_RS00420 (SR187_0440) - 70147..70413 (+) 267 WP_120171189.1 IreB family regulatory phosphoprotein -
  SR187_RS00425 (SR187_0445) ruvX 70413..70832 (+) 420 WP_032537883.1 Holliday junction resolvase RuvX -
  SR187_RS00430 (SR187_0450) - 70844..71149 (+) 306 WP_024532328.1 DUF1292 domain-containing protein -
  SR187_RS00435 (SR187_0455) - 71524..72069 (+) 546 WP_231996437.1 nucleotidyltransferase family protein -
  SR187_RS00440 (SR187_0460) comX/sigX 72162..72632 (+) 471 WP_024532329.1 sigma-70 family RNA polymerase sigma factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42435.46 Da        Isoelectric Point: 4.6716

>NTDB_id=69421 SR187_RS00405 WP_120171188.1 66740..67921(+) (cinA) [Streptococcus ruminantium strain GUT-187]
MKAELIAVGTEILTGQIVNTNTQFLSEKCAELGIDVYFHTSVGDNQGRLLQVLDIASRRSDLVILCGGLGPTEDDLTKQT
LARFLGKELVLDEQAKLKLDRFFASRPGRIRTPNNERQAQIVAGSTPLQNPAGLAVGGLIEQEGITYVVLPGPPSELKAM
FTTSLLPMLGNSHSQLYSRVLRFFGIGESQLVTILADLIDNQTNPTLAPYAKVGEVTLRLSTKATCQEEADQVLDRLETQ
ILQRDKLAEYFYAYGEENSLVKLVATSLAGKEQTLAVWEQGTGGLLQAELSLALAEQPYFIGGSVVGQKGADSGNLSVQA
SGIRDDLQADLGLAMSVFIKPSSTVDNVLAKISLALSSPSGVIQKELDLGGYSWQHIRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=69421 SR187_RS00405 WP_120171188.1 66740..67921(+) (cinA) [Streptococcus ruminantium strain GUT-187]
ATGAAAGCAGAACTAATCGCTGTTGGAACGGAGATTTTAACAGGGCAGATTGTTAATACGAATACTCAGTTTCTATCCGA
AAAATGTGCAGAGCTGGGAATTGATGTCTACTTCCACACAAGTGTTGGAGACAACCAAGGTAGACTTTTACAGGTGCTGG
ATATAGCCAGTAGACGCAGTGATTTGGTCATTCTATGTGGAGGTCTTGGCCCTACGGAAGATGATTTAACCAAACAAACA
TTAGCTCGATTTTTAGGGAAAGAATTAGTTTTGGATGAGCAGGCCAAGCTTAAATTAGACCGTTTTTTTGCTAGTCGTCC
AGGTCGTATTCGCACACCTAACAATGAACGTCAGGCACAGATTGTAGCAGGAAGTACCCCCTTGCAAAATCCTGCTGGTT
TAGCCGTTGGGGGATTGATTGAGCAAGAAGGAATAACCTATGTTGTACTTCCAGGCCCTCCGAGTGAGCTGAAAGCTATG
TTTACTACCAGTCTATTGCCGATGCTAGGCAATTCTCATAGCCAACTTTACTCACGGGTTCTGAGATTTTTTGGTATTGG
AGAAAGTCAGCTGGTGACGATTTTAGCAGATTTGATTGATAATCAGACTAATCCAACTTTAGCACCTTATGCTAAAGTCG
GTGAAGTCACCTTGCGCCTGTCTACCAAAGCTACTTGCCAAGAAGAAGCAGATCAAGTATTGGATCGTTTAGAAACACAA
ATTTTGCAACGTGATAAACTAGCAGAGTATTTCTATGCCTATGGTGAAGAAAATAGTCTGGTGAAATTGGTGGCGACCAG
CTTGGCGGGGAAAGAGCAAACTCTGGCTGTATGGGAACAGGGGACGGGTGGGCTCTTACAAGCAGAATTGAGTTTGGCGC
TGGCCGAACAGCCTTATTTTATCGGAGGTAGTGTTGTTGGTCAGAAAGGAGCTGATTCGGGCAATTTGTCTGTTCAAGCA
AGCGGTATTCGTGACGATCTACAAGCCGATTTAGGTTTAGCTATGTCGGTTTTTATCAAGCCGTCCTCAACGGTAGACAA
CGTTCTTGCCAAGATCTCACTGGCCTTATCAAGTCCTTCTGGAGTTATTCAAAAGGAGCTAGATTTGGGAGGTTATTCAT
GGCAACATATCCGTCAACTAGCTTGTTTACAAGCTCTAGATTTTGTACGAAATACTTTGTGA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2Z5TTG8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

78.626

100

0.786
  cinA Streptococcus mitis SK321

55.288

100

0.585
  cinA Streptococcus mitis NCTC 12261

54.808

100

0.58
  cinA Streptococcus mutans UA159

54.988

100

0.575
  cinA Streptococcus pneumoniae TIGR4

54.327

100

0.575
  cinA Streptococcus pneumoniae Rx1

54.327

100

0.575
  cinA Streptococcus pneumoniae R6

54.327

100

0.575
  cinA Streptococcus pneumoniae D39

54.087

100

0.573
  cinA Bacillus subtilis subsp. subtilis str. 168

48.208

78.117

0.377

Multiple sequence alignment