NTDB

Overview

Name	comGB/cglB	Type	Machinery gene
Locus tag	M9H69_RS01180	Genome accession	NZ_CP097843
Coordinates	212318..213334 (+)	Length	338 a.a.
NCBI ID	WP_213988901.1	Uniprot ID	-
Organism	Streptococcus oralis strain HP01
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 207318..218334

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
M9H69_RS01160 (M9H69_01160)	-	207736..209553 (+)	1818	WP_250315696.1	acyltransferase family protein	-
M9H69_RS01165 (M9H69_01165)	nagA	209694..210845 (+)	1152	WP_084876957.1	N-acetylglucosamine-6-phosphate deacetylase	-
M9H69_RS01170 (M9H69_01170)	-	210999..211364 (+)	366	WP_000286396.1	DUF1033 family protein	-
M9H69_RS01175 (M9H69_01175)	comGA/cglA/cilD	211429..212370 (+)	942	WP_213988900.1	competence type IV pilus ATPase ComGA	Machinery gene
M9H69_RS01180 (M9H69_01180)	comGB/cglB	212318..213334 (+)	1017	WP_213988901.1	competence type IV pilus assembly protein ComGB	Machinery gene
M9H69_RS01185 (M9H69_01185)	comGC/cglC	213336..213659 (+)	324	WP_000735798.1	competence type IV pilus major pilin ComGC	Machinery gene
M9H69_RS01190 (M9H69_01190)	comGD/cglD	213622..214056 (+)	435	WP_250315697.1	competence type IV pilus minor pilin ComGD	Machinery gene
M9H69_RS01195 (M9H69_01195)	comGE/cglE	214019..214321 (+)	303	WP_167266658.1	competence type IV pilus minor pilin ComGE	Machinery gene
M9H69_RS01200 (M9H69_01200)	comGF/cglF	214284..214745 (+)	462	WP_000250702.1	competence type IV pilus minor pilin ComGF	Machinery gene
M9H69_RS01205 (M9H69_01205)	comGG/cglG	214723..215136 (+)	414	WP_195217483.1	competence type IV pilus minor pilin ComGG	Machinery gene
M9H69_RS01210 (M9H69_01210)	-	215169..215759 (+)	591	WP_250315698.1	class I SAM-dependent methyltransferase	-
M9H69_RS01215 (M9H69_01215)	comYH	215818..216765 (+)	948	WP_250315699.1	class I SAM-dependent methyltransferase	Machinery gene
M9H69_RS01220 (M9H69_01220)	-	216823..218013 (+)	1191	WP_250315700.1	acetate kinase	-

Sequence

Protein

Download Length: 338 a.a. Molecular weight: 38497.63 Da Isoelectric Point: 9.6790

                                >NTDB_id=692898 M9H69_RS01180 WP_213988901.1 212318..213334(+) (comGB/cglB) [Streptococcus oralis strain HP01]

MDISQVFRLKRKKLATAKQKKIITLFNNLFSSGFHLVEIISFLGRSALLEKDYVAQMHQGLSQGKSFSEMMESLGFSSAI

VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF

LGLVLVCSLSLLLALTFYKRSSKMRVFSMLARIPFLGIFVQTYLTAYYAREWGNMISQGMDLTQIFQIMREQGSQLFKEI

GQDLAQALQNGREFSPTIATYPFFKKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV

LLYAAMLMPMYQNMEVNF

Nucleotide

Download Length: 1017 bp

                                >NTDB_id=692898 M9H69_RS01180 WP_213988901.1 212318..213334(+) (comGB/cglB) [Streptococcus oralis strain HP01]

ATGGACATATCACAAGTCTTCAGGCTGAAACGGAAAAAATTAGCTACAGCTAAGCAGAAGAAAATCATCACCTTGTTTAA

CAACCTCTTCTCCAGTGGCTTTCATTTGGTGGAAATTATTTCTTTTTTGGGCAGAAGTGCCCTGCTGGAAAAGGACTATG

TGGCCCAGATGCACCAAGGCTTGTCTCAGGGGAAATCCTTCTCAGAAATGATGGAAAGTTTGGGGTTTTCAAGTGCCATT

GTCACTCAGTTATCCCTAGCTGAAGTTCATGGAAATCTCCACCTGAGTCTGGGAAAGATAGAAGAATATCTGGACAATCT

GGCCAAGGTCAAGAAAAAGTTAATTGAAGTGGCGACCTATCCCTTGATTTTGCTGGGATTTCTCCTGCTAATCATGCTGG

GATTAAGAAACTATTTGCTCCCCCAACTGGACAGTAGCAATATCGCTACTCAAATCATTGGCAATCTGCCACAAATTTTT

CTGGGACTAGTGTTGGTTTGCTCTCTATCTTTACTTTTAGCCCTCACTTTTTACAAAAGAAGTTCCAAGATGCGGGTCTT

TTCGATGTTAGCGCGGATTCCCTTTCTGGGAATCTTTGTCCAGACTTATCTGACAGCCTATTACGCGCGTGAATGGGGCA

ATATGATTTCGCAGGGAATGGATCTGACGCAGATTTTTCAGATTATGCGGGAACAAGGTTCCCAGCTCTTTAAAGAAATC

GGTCAAGATCTGGCTCAAGCTCTGCAAAATGGCCGCGAATTTTCTCCAACCATAGCGACCTATCCTTTCTTTAAAAAGGA

GTTGAGTCTCATCATAGAGTATGGAGAAGTCAAGTCCAAGCTGGGGAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG

AAGCCTTTTTTACCCGAGTCAACCGCACCATGAACTTAGTACAGCCACTGGTTTTTATCTTTGTGGCCCTGATTATCGTT

TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGB/cglB	Streptococcus mitis SK321	93.491	100	0.935
comGB/cglB	Streptococcus mitis NCTC 12261	92.604	100	0.926
comGB/cglB	Streptococcus pneumoniae Rx1	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae D39	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae R6	90.828	100	0.908
comGB/cglB	Streptococcus pneumoniae TIGR4	90.828	100	0.908
comYB	Streptococcus gordonii str. Challis substr. CH1	73.214	99.408	0.728
comYB	Streptococcus mutans UA140	58.307	94.379	0.55
comYB	Streptococcus mutans UA159	58.307	94.379	0.55
comGB	Lactococcus lactis subsp. cremoris KW2	51.775	100	0.518

Detailed information NTG0692898