Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   M9H69_RS01215 Genome accession   NZ_CP097843
Coordinates   215818..216765 (+) Length   315 a.a.
NCBI ID   WP_250315699.1    Uniprot ID   -
Organism   Streptococcus oralis strain HP01     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 210818..221765
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M9H69_RS01170 (M9H69_01170) - 210999..211364 (+) 366 WP_000286396.1 DUF1033 family protein -
  M9H69_RS01175 (M9H69_01175) comGA/cglA/cilD 211429..212370 (+) 942 WP_213988900.1 competence type IV pilus ATPase ComGA Machinery gene
  M9H69_RS01180 (M9H69_01180) comGB/cglB 212318..213334 (+) 1017 WP_213988901.1 competence type IV pilus assembly protein ComGB Machinery gene
  M9H69_RS01185 (M9H69_01185) comGC/cglC 213336..213659 (+) 324 WP_000735798.1 competence type IV pilus major pilin ComGC Machinery gene
  M9H69_RS01190 (M9H69_01190) comGD/cglD 213622..214056 (+) 435 WP_250315697.1 competence type IV pilus minor pilin ComGD Machinery gene
  M9H69_RS01195 (M9H69_01195) comGE/cglE 214019..214321 (+) 303 WP_167266658.1 competence type IV pilus minor pilin ComGE Machinery gene
  M9H69_RS01200 (M9H69_01200) comGF/cglF 214284..214745 (+) 462 WP_000250702.1 competence type IV pilus minor pilin ComGF Machinery gene
  M9H69_RS01205 (M9H69_01205) comGG/cglG 214723..215136 (+) 414 WP_195217483.1 competence type IV pilus minor pilin ComGG Machinery gene
  M9H69_RS01210 (M9H69_01210) - 215169..215759 (+) 591 WP_250315698.1 class I SAM-dependent methyltransferase -
  M9H69_RS01215 (M9H69_01215) comYH 215818..216765 (+) 948 WP_250315699.1 class I SAM-dependent methyltransferase Machinery gene
  M9H69_RS01220 (M9H69_01220) - 216823..218013 (+) 1191 WP_250315700.1 acetate kinase -
  M9H69_RS01225 (M9H69_01225) rnpA 218162..218533 (+) 372 WP_000748120.1 ribonuclease P protein component -
  M9H69_RS01230 (M9H69_01230) - 218508..219335 (+) 828 WP_250315701.1 membrane protein insertase YidC -
  M9H69_RS01235 (M9H69_01235) jag 219350..220336 (+) 987 WP_250315702.1 RNA-binding cell elongation regulator Jag/EloR -
  M9H69_RS01240 (M9H69_01240) - 220392..221015 (+) 624 WP_250315703.1 ribonuclease P -

Sequence

Protein


Download         Length: 315 a.a.        Molecular weight: 35575.55 Da        Isoelectric Point: 4.2623

>NTDB_id=692904 M9H69_RS01215 WP_250315699.1 215818..216765(+) (comYH) [Streptococcus oralis strain HP01]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETKLEQVKENNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDTIALLLVLIVEELFDQEEISILEMGSGMGILGATFLTSLAKKVDYLGVEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPIGYYPDDTIASRYHVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKGWLKEEAQLAAMITLPENLFSQDSNSKAIFVLQKKGLKAVEPFVYPLNNLRDSQELVDFKEKFQNWSQYS

Nucleotide


Download         Length: 948 bp        

>NTDB_id=692904 M9H69_RS01215 WP_250315699.1 215818..216765(+) (comYH) [Streptococcus oralis strain HP01]
ATGGATTTTGAAAAAATTGAACAAGCTTATACGTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTAGAGCAAAATAGTATCTACCTAGATGGCGAGACCAAGCTAGAGCAGGTCAAGGAGAATAATC
AAGCCCTTAAACGCCTAGCACTTCGCAAGGAAGAGTGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCAGGACAAACG
GAGCCTTTACAGGCCAATCACCAGTTTACACCGGATACCATTGCCCTCCTCTTGGTACTTATTGTGGAAGAGTTGTTTGA
TCAAGAGGAAATTAGCATCCTCGAAATGGGTTCTGGCATGGGGATTCTGGGCGCTACTTTCTTGACTTCTCTTGCTAAAA
AGGTGGATTACTTGGGAGTCGAAGTGGATGATTTGCTAATTGATCTGGCGGCTAGTATGGCAGATGTGATCGGTTTGCAG
GCAGGATTTGTTCAAGGTGACGCCGTTCGTCCGCAAATGCTCAAAGAAAGCGACGTGGTCATCAGTGACTTACCTATCGG
TTATTACCCAGACGACACTATCGCTTCACGCTATCATGTAGCTTCTAGCCAAGAACATACCTATGCCCACCATTTGCTGA
TGGAGCAAGGCCTCAAGTACCTTAAGTCAGATGGTTATGCTATTTTTCTAGCTCCGAGTGATTTATTGACCAGTCCTCAA
AGTGATTTGCTGAAAGGGTGGTTGAAAGAGGAGGCCCAACTTGCAGCCATGATTACACTACCAGAAAATCTCTTTAGTCA
AGATAGCAATTCTAAGGCTATTTTTGTTCTACAAAAGAAAGGATTAAAAGCTGTAGAACCTTTCGTGTATCCACTGAATA
ATCTACGTGACTCTCAGGAATTGGTAGACTTTAAAGAAAAGTTTCAAAATTGGAGTCAATATTCATGA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-281)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

99.365

0.543
  comYH Streptococcus mutans UA159

54.313

99.365

0.54