Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2906_RS12895 Genome accession   NZ_CP097048
Coordinates   2678775..2680019 (-) Length   414 a.a.
NCBI ID   WP_010710870.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AT22     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2673775..2685019
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2906_RS12875 (M2906_12825) - 2674245..2674631 (-) 387 WP_002359008.1 YlbF family regulator -
  M2906_RS12880 (M2906_12830) - 2674705..2675502 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  M2906_RS12885 (M2906_12835) rny 2675662..2677218 (-) 1557 WP_002354863.1 ribonuclease Y -
  M2906_RS12890 (M2906_12840) recA 2677615..2678661 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  M2906_RS12895 (M2906_12845) cinA 2678775..2680019 (-) 1245 WP_010710870.1 competence/damage-inducible protein A Machinery gene
  M2906_RS12900 (M2906_12850) - 2680211..2681416 (+) 1206 WP_248868768.1 hypothetical protein -
  M2906_RS12905 (M2906_12855) - 2681643..2681753 (-) 111 Protein_2532 type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family -
  M2906_RS12910 (M2906_12860) - 2682477..2682740 (-) 264 WP_002396818.1 hypothetical protein -
  M2906_RS12915 (M2906_12865) - 2682744..2683994 (-) 1251 WP_346429039.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45193.29 Da        Isoelectric Point: 4.6698

>NTDB_id=686668 M2906_RS12895 WP_010710870.1 2678775..2680019(-) (cinA) [Enterococcus faecalis strain AT22]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=686668 M2906_RS12895 WP_010710870.1 2678775..2680019(-) (cinA) [Enterococcus faecalis strain AT22]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTTCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTT
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCCGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.537

100

0.527
  cinA Streptococcus mitis NCTC 12261

51.3

100

0.524
  cinA Streptococcus pneumoniae TIGR4

50.591

100

0.517
  cinA Streptococcus pneumoniae D39

50.355

100

0.514
  cinA Streptococcus pneumoniae R6

50.118

100

0.512
  cinA Streptococcus pneumoniae Rx1

50.118

100

0.512
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437