Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2911_RS12625 Genome accession   NZ_CP097038
Coordinates   2655011..2656255 (-) Length   414 a.a.
NCBI ID   WP_002370126.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AT39     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2650011..2661255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2911_RS12605 (M2911_12605) - 2650481..2650867 (-) 387 WP_002359008.1 YlbF family regulator -
  M2911_RS12610 (M2911_12610) - 2650941..2651738 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  M2911_RS12615 (M2911_12615) rny 2651898..2653454 (-) 1557 WP_002354863.1 ribonuclease Y -
  M2911_RS12620 (M2911_12620) recA 2653851..2654897 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  M2911_RS12625 (M2911_12625) cinA 2655011..2656255 (-) 1245 WP_002370126.1 competence/damage-inducible protein A Machinery gene
  M2911_RS12630 (M2911_12630) - 2656447..2657646 (+) 1200 WP_002370127.1 hypothetical protein -
  M2911_RS12635 (M2911_12635) - 2657726..2658355 (-) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  M2911_RS12640 (M2911_12640) - 2658414..2658839 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  M2911_RS12645 (M2911_12645) - 2658928..2659311 (-) 384 WP_002358999.1 YccF domain-containing protein -
  M2911_RS12650 (M2911_12650) - 2659475..2660266 (+) 792 WP_033786675.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45247.39 Da        Isoelectric Point: 4.7771

>NTDB_id=686493 M2911_RS12625 WP_002370126.1 2655011..2656255(-) (cinA) [Enterococcus faecalis strain AT39]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMRENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=686493 M2911_RS12625 WP_002370126.1 2655011..2656255(-) (cinA) [Enterococcus faecalis strain AT39]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGAGGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTAATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.306

100

0.522
  cinA Streptococcus mitis NCTC 12261

51.069

100

0.519
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.119

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.881

100

0.507
  cinA Streptococcus pneumoniae R6

49.881

100

0.507
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.068

99.758

0.44