Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2914_RS12485 Genome accession   NZ_CP097031
Coordinates   2597514..2598758 (-) Length   414 a.a.
NCBI ID   WP_116495148.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AT41     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2592514..2603758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2914_RS12465 (M2914_12465) - 2592984..2593370 (-) 387 WP_002359008.1 YlbF family regulator -
  M2914_RS12470 (M2914_12470) - 2593444..2594241 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  M2914_RS12475 (M2914_12475) rny 2594401..2595957 (-) 1557 WP_002354863.1 ribonuclease Y -
  M2914_RS12480 (M2914_12480) recA 2596354..2597400 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  M2914_RS12485 (M2914_12485) cinA 2597514..2598758 (-) 1245 WP_116495148.1 competence/damage-inducible protein A Machinery gene
  M2914_RS12490 (M2914_12490) - 2598950..2600149 (+) 1200 WP_116495147.1 hypothetical protein -
  M2914_RS12495 (M2914_12495) - 2600229..2600858 (-) 630 WP_161970599.1 NAD(P)-dependent oxidoreductase -
  M2914_RS12500 (M2914_12500) - 2600917..2601342 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  M2914_RS12505 (M2914_12505) - 2601431..2601814 (-) 384 WP_002358999.1 YccF domain-containing protein -
  M2914_RS12510 (M2914_12510) - 2601978..2602769 (+) 792 WP_002367471.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45221.35 Da        Isoelectric Point: 4.7248

>NTDB_id=686421 M2914_RS12485 WP_116495148.1 2597514..2598758(-) (cinA) [Enterococcus faecalis strain AT41]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPREEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=686421 M2914_RS12485 WP_116495148.1 2597514..2598758(-) (cinA) [Enterococcus faecalis strain AT41]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCAACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCTATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACGAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACTGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGCTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

43.72

100

0.437