Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2918_RS12300 Genome accession   NZ_CP097020
Coordinates   2589496..2590740 (-) Length   414 a.a.
NCBI ID   WP_002378831.1    Uniprot ID   -
Organism   Enterococcus faecalis strain AT46a     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2584496..2595740
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2918_RS12275 (M2918_12275) - 2584810..2586273 (-) 1464 WP_248848854.1 glycoside hydrolase family 1 protein -
  M2918_RS12280 (M2918_12280) - 2586255..2586596 (-) 342 WP_002359005.1 PTS lactose/cellobiose transporter subunit IIA -
  M2918_RS12285 (M2918_12285) - 2586616..2587866 (-) 1251 WP_174113969.1 PTS transporter subunit EIIC -
  M2918_RS12290 (M2918_12290) - 2587871..2588176 (-) 306 WP_010821936.1 hypothetical protein -
  M2918_RS12295 (M2918_12295) recA 2588336..2589382 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  M2918_RS12300 (M2918_12300) cinA 2589496..2590740 (-) 1245 WP_002378831.1 competence/damage-inducible protein A Machinery gene
  M2918_RS12305 (M2918_12305) - 2590932..2592131 (+) 1200 WP_002370127.1 hypothetical protein -
  M2918_RS12310 (M2918_12310) - 2592211..2592840 (-) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  M2918_RS12315 (M2918_12315) - 2592899..2593324 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  M2918_RS12320 (M2918_12320) - 2593413..2593796 (-) 384 WP_104675218.1 YccF domain-containing protein -
  M2918_RS12325 (M2918_12325) - 2593960..2594751 (+) 792 WP_010819084.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45206.33 Da        Isoelectric Point: 4.7172

>NTDB_id=686275 M2918_RS12300 WP_002378831.1 2589496..2590740(-) (cinA) [Enterococcus faecalis strain AT46a]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLINAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPIEGQPTGTVWIGLAEEGQPTIAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=686275 M2918_RS12300 WP_002378831.1 2589496..2590740(-) (cinA) [Enterococcus faecalis strain AT46a]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTTGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTACACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTAATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCAATCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCATTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.392

100

0.529
  cinA Streptococcus mitis SK321

51.3

100

0.524
  cinA Streptococcus mitis NCTC 12261

51.064

100

0.522
  cinA Streptococcus pneumoniae TIGR4

50.355

100

0.514
  cinA Streptococcus pneumoniae D39

50.118

100

0.512
  cinA Streptococcus pneumoniae R6

49.882

100

0.51
  cinA Streptococcus pneumoniae Rx1

49.882

100

0.51
  cinA Bacillus subtilis subsp. subtilis str. 168

48.276

98.068

0.473
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437