Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   M2925_RS12045 Genome accession   NZ_CP097004
Coordinates   2536891..2538135 (-) Length   414 a.a.
NCBI ID   WP_010715478.1    Uniprot ID   -
Organism   Enterococcus faecalis strain LS05-2     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2531891..2543135
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M2925_RS12020 (M2925_12020) - 2532205..2533668 (-) 1464 WP_219259713.1 glycoside hydrolase family 1 protein -
  M2925_RS12025 (M2925_12025) - 2533650..2533991 (-) 342 WP_010816846.1 PTS lactose/cellobiose transporter subunit IIA -
  M2925_RS12030 (M2925_12030) - 2534011..2535261 (-) 1251 WP_002383206.1 PTS transporter subunit EIIC -
  M2925_RS12035 (M2925_12035) - 2535266..2535571 (-) 306 WP_010715477.1 hypothetical protein -
  M2925_RS12040 (M2925_12040) recA 2535731..2536777 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  M2925_RS12045 (M2925_12045) cinA 2536891..2538135 (-) 1245 WP_010715478.1 competence/damage-inducible protein A Machinery gene
  M2925_RS12050 (M2925_12050) - 2538327..2539532 (+) 1206 WP_219259711.1 hypothetical protein -
  M2925_RS12055 (M2925_12055) - 2539611..2540240 (-) 630 WP_002354854.1 NAD(P)-dependent oxidoreductase -
  M2925_RS12060 (M2925_12060) - 2540299..2540724 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  M2925_RS12065 (M2925_12065) - 2540813..2541196 (-) 384 WP_002358999.1 YccF domain-containing protein -
  M2925_RS12070 (M2925_12070) - 2541360..2542151 (+) 792 WP_002367471.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45177.29 Da        Isoelectric Point: 4.6698

>NTDB_id=686059 M2925_RS12045 WP_010715478.1 2536891..2538135(-) (cinA) [Enterococcus faecalis strain LS05-2]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGATSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKILAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=686059 M2925_RS12045 WP_010715478.1 2536891..2538135(-) (cinA) [Enterococcus faecalis strain LS05-2]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGCGATAACGGCGGCCGCTTAGAAACGTTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGACTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTTGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGACCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCGCAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGATTTTAGCTAAAGTGGGGGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAGCATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCACGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGCGCGGTTATG
CGAGGGTTAGATCTTTTGCGACGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(258-409)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.871

100

0.534
  cinA Streptococcus mitis SK321

52.009

100

0.531
  cinA Streptococcus mitis NCTC 12261

51.773

100

0.529
  cinA Streptococcus pneumoniae TIGR4

51.064

100

0.522
  cinA Streptococcus pneumoniae D39

50.827

100

0.519
  cinA Streptococcus pneumoniae R6

50.591

100

0.517
  cinA Streptococcus pneumoniae Rx1

50.591

100

0.517
  cinA Bacillus subtilis subsp. subtilis str. 168

48.768

98.068

0.478
  cinA Streptococcus suis isolate S10

44.282

99.275

0.44