Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC   Type   Machinery gene
Locus tag   CCX78_RS03240 Genome accession   NZ_AP017931
Coordinates   619096..619395 (+) Length   99 a.a.
NCBI ID   WP_011374999.1    Uniprot ID   Q38W25
Organism   Latilactobacillus sakei strain LK-145     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 614096..624395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCX78_RS03215 (LASAK_00635) - 615300..615692 (-) 393 WP_231952369.1 hypothetical protein -
  CCX78_RS03220 (LASAK_00636) - 615771..616271 (+) 501 WP_011375003.1 VanZ family protein -
  CCX78_RS03225 (LASAK_00637) - 616362..617093 (+) 732 WP_011375002.1 YebC/PmpR family DNA-binding transcriptional regulator -
  CCX78_RS03230 (LASAK_00638) comGA 617209..618099 (+) 891 WP_016265378.1 competence type IV pilus ATPase ComGA Machinery gene
  CCX78_RS03235 (LASAK_00639) comGB 618092..619099 (+) 1008 WP_011375000.1 type II secretion system F family protein Machinery gene
  CCX78_RS03240 (LASAK_00640) comGC 619096..619395 (+) 300 WP_011374999.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  CCX78_RS03245 (LASAK_00641) comGD 619367..619819 (+) 453 WP_035145016.1 competence type IV pilus minor pilin ComGD Machinery gene
  CCX78_RS03250 (LASAK_00642) comGE 619806..620111 (+) 306 WP_011374997.1 hypothetical protein Machinery gene
  CCX78_RS03255 (LASAK_00643) comGF 620077..620598 (+) 522 WP_112234088.1 competence type IV pilus minor pilin ComGF Machinery gene
  CCX78_RS03260 (LASAK_00644) - 620633..620899 (+) 267 WP_172425585.1 hypothetical protein -
  CCX78_RS03265 (LASAK_00645) - 621014..622033 (+) 1020 WP_231952370.1 class I SAM-dependent methyltransferase -
  CCX78_RS03270 (LASAK_00646) - 622055..623251 (+) 1197 WP_096584647.1 acetate/propionate family kinase -
  CCX78_RS03275 (LASAK_00647) - 623306..623764 (+) 459 WP_096584650.1 laaL -

Sequence

Protein


Download         Length: 99 a.a.        Molecular weight: 10994.02 Da        Isoelectric Point: 10.2663

>NTDB_id=68585 CCX78_RS03240 WP_011374999.1 619096..619395(+) (comGC) [Latilactobacillus sakei strain LK-145]
MKKKRKAFTLIEMVVVLAIIALLILLVAPNLGAQKQRAEKKTDQALVTTLQTQVELASDEIGHQIKSLDELTDKYISKDQ
LKHAKEKGITIEGGTVKQK

Nucleotide


Download         Length: 300 bp        

>NTDB_id=68585 CCX78_RS03240 WP_011374999.1 619096..619395(+) (comGC) [Latilactobacillus sakei strain LK-145]
ATGAAGAAAAAAAGAAAAGCTTTTACACTAATTGAAATGGTAGTTGTTCTTGCCATTATTGCGTTACTAATCTTATTAGT
TGCACCAAACCTAGGTGCTCAAAAACAGCGCGCGGAGAAGAAAACGGATCAAGCTTTGGTGACGACTTTGCAAACGCAAG
TTGAATTAGCTAGCGACGAGATTGGTCATCAAATTAAGAGTCTAGACGAATTAACGGATAAGTATATTTCAAAAGACCAA
TTAAAGCACGCAAAGGAGAAGGGGATTACAATTGAAGGCGGCACGGTTAAGCAAAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(2-27)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q38W25

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC Latilactobacillus sakei subsp. sakei 23K

100

100

1
  comGC/cglC Streptococcus pneumoniae TIGR4

45.349

86.869

0.394
  comGC/cglC Streptococcus pneumoniae Rx1

45.349

86.869

0.394
  comGC/cglC Streptococcus pneumoniae D39

45.349

86.869

0.394
  comGC/cglC Streptococcus pneumoniae R6

45.349

86.869

0.394
  comGC/cglC Streptococcus mitis NCTC 12261

44.186

86.869

0.384

Multiple sequence alignment