Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   EFW11_RS12735 Genome accession   NZ_AP017623
Coordinates   2550293..2551537 (-) Length   414 a.a.
NCBI ID   WP_096398053.1    Uniprot ID   -
Organism   Enterococcus faecalis strain W11     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2545293..2556537
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFW11_RS12710 (EFW11_2400) - 2545763..2546149 (-) 387 WP_002359008.1 RicAFT regulatory complex protein RicA family protein -
  EFW11_RS12715 (EFW11_2401) - 2546223..2547020 (-) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  EFW11_RS12720 (EFW11_2402) rny 2547180..2548736 (-) 1557 WP_002354863.1 ribonuclease Y -
  EFW11_RS12730 (EFW11_2403) recA 2549133..2550179 (-) 1047 WP_002354860.1 recombinase RecA Machinery gene
  EFW11_RS12735 (EFW11_2404) cinA 2550293..2551537 (-) 1245 WP_096398053.1 competence/damage-inducible protein A Machinery gene
  EFW11_RS12740 (EFW11_2405) - 2551729..2552934 (+) 1206 WP_096398054.1 hypothetical protein -
  EFW11_RS12745 (EFW11_2406) - 2553013..2553642 (-) 630 WP_025188758.1 NAD(P)-dependent oxidoreductase -
  EFW11_RS12750 (EFW11_2407) - 2553701..2554126 (-) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  EFW11_RS12755 (EFW11_2408) - 2554215..2554598 (-) 384 WP_002358999.1 YccF domain-containing protein -
  EFW11_RS12760 (EFW11_2409) - 2554762..2555553 (+) 792 WP_002372754.1 hypothetical protein -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45180.29 Da        Isoelectric Point: 4.6698

>NTDB_id=68186 EFW11_RS12735 WP_096398053.1 2550293..2551537(-) (cinA) [Enterococcus faecalis strain W11]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQTGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=68186 EFW11_RS12735 WP_096398053.1 2550293..2551537(-) (cinA) [Enterococcus faecalis strain W11]
ATGAAAGCAGAAATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCTATTGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTCGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGGCCGCCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCAAGAGTCTTGCGTTTTTATGG
GATTGGTGAATCACAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAACCGGACAAACCGTCACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGGGGGTTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437

Multiple sequence alignment