Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilQ   Type   Machinery gene
Locus tag   MZN67_RS04725 Genome accession   NZ_CP096116
Coordinates   1041488..1043584 (+) Length   698 a.a.
NCBI ID   WP_011215098.1    Uniprot ID   Q5WXX7
Organism   Legionella pneumophila subsp. pneumophila strain DFS-2111020037     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1036488..1048584
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MZN67_RS04700 (MZN67_04675) ravI 1037250..1038257 (-) 1008 WP_027266406.1 Dot/Icm T4SS effector RavI -
  MZN67_RS04705 (MZN67_04680) pilM 1038674..1039738 (+) 1065 WP_011215094.1 type IV pilus assembly protein PilM Machinery gene
  MZN67_RS04710 (MZN67_04685) pilN 1039742..1040290 (+) 549 WP_010946663.1 PilN domain-containing protein Machinery gene
  MZN67_RS04715 (MZN67_04690) pilO 1040304..1040903 (+) 600 WP_011215096.1 type 4a pilus biogenesis protein PilO Machinery gene
  MZN67_RS04720 (MZN67_04695) pilP 1040900..1041484 (+) 585 WP_161504771.1 pilus assembly protein PilP Machinery gene
  MZN67_RS04725 (MZN67_04700) pilQ 1041488..1043584 (+) 2097 WP_011215098.1 type IV pilus secretin PilQ Machinery gene
  MZN67_RS04730 (MZN67_04705) aroK 1044030..1044557 (+) 528 WP_010946667.1 shikimate kinase AroK -
  MZN67_RS04735 (MZN67_04710) aroB 1044544..1045653 (+) 1110 WP_374152241.1 3-dehydroquinate synthase -
  MZN67_RS04740 (MZN67_04715) - 1045650..1047101 (+) 1452 WP_161504773.1 SPOR domain-containing protein -
  MZN67_RS04745 (MZN67_04720) - 1047210..1047641 (+) 432 WP_010946670.1 universal stress protein -

Sequence

Protein


Download         Length: 698 a.a.        Molecular weight: 77473.77 Da        Isoelectric Point: 9.5345

>NTDB_id=679452 MZN67_RS04725 WP_011215098.1 1041488..1043584(+) (pilQ) [Legionella pneumophila subsp. pneumophila strain DFS-2111020037]
MRKIIAILILISASLSMAYSKDNSLISVKVLPLPENRVRIDFQFSKPLKQLPASFITQKPPRLVLDFISTDMQIPSDQKT
KTIQLGSLHSYNIVAVGDRVRAILELDRSVSYSGSTAGSVYSLVLNGKSNDLFENSKEVFITNQVVNAKHEIKRIDFRGI
EKQGGRVLIDVSDTGIPIDVTQVGKEIVVNFLNTKIPLNLMKRYDVSDFHSPVQIITMQQEGKKVRMTILSKGDYGHFVY
QVNKQFMVDVFPLTAEEIRQAKLKKQVFTGKRISLNFQNISIRAVLQLLADFTGINMVVSDKVQGDITLRLNDIPWDQAL
DIILTTQGLDKRRKGNVMLIDTKASMDKMEEEQLKSQQTIEKLEPIRSDLIQINYAKAADIAVLIKDKQNSLLSDRGKIS
VDARTNTIWIQDTGTKIEEVRELIKQLDIPVKQVLIEARIVEVTKDFSQDIGIRWGVSRPTHLSGTLEGANELARGTAPA
NVVPLERRLNLDLAAAPLTGATPASVGIALAKLNDNILLDLELSALESEGRAELISSPRLITTNQQAAVIESGEEIPYQE
ATSSGATAVAFKKAVLSLKVTPQITPDGKILMDLQINQDTPSPQTFLGVPAIITKEIQTNVLVNNGQTIVLGGIYKQDKN
KVINRIPFFGELPVVGILFSNRQITLKNEELLIFITPRIITNALSITTIEGREKDVYK

Nucleotide


Download         Length: 2097 bp        

>NTDB_id=679452 MZN67_RS04725 WP_011215098.1 1041488..1043584(+) (pilQ) [Legionella pneumophila subsp. pneumophila strain DFS-2111020037]
GTGAGAAAAATTATCGCGATTTTGATATTAATTAGTGCCAGTTTGAGTATGGCATATTCTAAAGATAATTCGCTCATTTC
AGTAAAAGTATTGCCATTGCCCGAAAACAGAGTGCGTATTGATTTTCAATTTTCCAAGCCCTTAAAGCAGTTGCCTGCAA
GCTTTATTACTCAAAAGCCGCCCCGTCTGGTGTTAGATTTTATCAGCACTGATATGCAAATTCCTTCGGATCAGAAAACT
AAAACTATTCAATTAGGCTCATTACACAGTTATAACATTGTTGCTGTTGGGGATAGAGTAAGGGCCATATTGGAACTGGA
TCGTTCAGTATCCTATTCTGGCAGTACGGCGGGTTCCGTTTATAGCCTTGTCCTGAATGGTAAAAGCAATGATTTATTTG
AAAATAGCAAGGAGGTATTCATAACGAACCAGGTTGTGAACGCCAAGCATGAAATTAAAAGAATTGATTTTCGTGGTATA
GAAAAGCAGGGCGGTAGAGTTTTAATTGATGTTTCTGATACGGGTATTCCAATTGATGTAACTCAAGTTGGGAAAGAAAT
AGTCGTTAATTTCCTGAATACCAAGATCCCTTTGAATTTAATGAAACGGTATGATGTTTCTGATTTTCACAGCCCTGTGC
AGATTATTACGATGCAACAGGAAGGCAAAAAGGTTCGCATGACTATCCTCAGCAAAGGGGATTATGGACATTTTGTTTAT
CAGGTCAATAAACAATTTATGGTCGATGTCTTTCCTTTAACTGCGGAAGAAATTCGTCAGGCGAAATTGAAGAAACAGGT
ATTTACTGGTAAACGTATTTCTTTAAATTTCCAGAATATTAGTATTCGAGCTGTACTTCAATTGCTGGCAGATTTTACTG
GAATCAATATGGTTGTCAGCGACAAAGTACAAGGAGATATTACGCTTAGATTAAATGATATCCCCTGGGATCAGGCTTTG
GATATCATTTTAACCACACAAGGGCTAGATAAGCGCAGAAAGGGCAACGTCATGTTGATAGATACCAAGGCCTCCATGGA
TAAAATGGAGGAAGAACAACTCAAAAGTCAACAGACAATTGAAAAACTTGAGCCTATCCGTTCTGATTTAATACAAATTA
ATTATGCAAAGGCAGCAGATATTGCTGTTTTGATCAAGGATAAGCAAAATTCCCTATTATCAGACAGGGGAAAAATAAGT
GTTGATGCCAGAACGAATACAATCTGGATTCAGGATACTGGCACCAAAATTGAGGAAGTAAGGGAACTGATAAAGCAATT
GGATATCCCCGTTAAGCAAGTGCTTATTGAGGCAAGAATTGTTGAAGTGACTAAAGATTTTAGCCAGGATATTGGGATAC
GCTGGGGGGTATCAAGACCAACTCACTTAAGTGGTACACTGGAAGGTGCTAACGAGTTAGCGAGAGGCACAGCACCAGCC
AATGTTGTCCCCTTGGAAAGAAGATTAAATCTTGATTTGGCAGCTGCTCCTTTAACCGGAGCTACACCGGCCTCGGTAGG
TATTGCGCTAGCTAAACTTAATGATAACATTCTGCTTGATCTGGAATTGTCTGCTTTGGAAAGCGAAGGGCGTGCTGAGT
TAATATCCAGTCCTCGCTTGATTACTACGAATCAACAGGCAGCAGTCATAGAGTCTGGTGAGGAGATTCCCTATCAGGAG
GCAACATCAAGTGGAGCGACTGCTGTTGCATTTAAAAAAGCGGTATTGAGTTTGAAAGTTACCCCGCAAATTACGCCTGA
TGGTAAAATTTTGATGGATTTACAGATAAATCAGGATACTCCTTCCCCACAAACATTCCTTGGTGTTCCAGCAATAATAA
CAAAGGAGATTCAGACGAATGTTCTGGTTAATAATGGACAAACCATAGTACTTGGGGGTATTTATAAGCAAGATAAGAAC
AAGGTAATCAATAGAATTCCTTTCTTTGGTGAGTTGCCTGTTGTCGGTATTTTATTTAGTAATAGACAAATCACATTGAA
AAATGAAGAATTACTTATCTTTATTACACCAAGAATAATAACGAATGCCTTATCGATTACAACGATAGAGGGACGCGAGA
AAGATGTTTATAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(370-433)

Bacterial type II and III secretion system protein (Secretin)

(525-680)

AMIN domain (AMIN)

(39-113)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5WXX7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilQ Legionella pneumophila strain Lp02

99.857

100

0.999
  pilQ Legionella pneumophila strain ERS1305867

99.713

100

0.997
  pilQ Pseudomonas aeruginosa PAK

37.73

100

0.381
  comQ Acinetobacter baylyi ADP1

38.574

98.424

0.38
  pilQ Acinetobacter baumannii strain A118

35.095

100

0.371
  pilQ Acinetobacter baumannii D1279779

35.095

100

0.371