Detailed information NTG0677034

Bioinformatically predicted

Overview

• Name: cinA
• Type: Machinery gene
• Locus tag: MU520_RS09845
• Genome accession: NZ_CP095463
• Coordinates: 2006878..2008059 (-)
• Length: 393 a.a.
• NCBI ID: WP_012774894.1
• Uniprot ID: -
• Organism: Streptococcus suis strain TJS56
• Function: require for competence (predicted from homology) Unclear

Genomic Context

Location: 2001878..2013059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MU520_RS09805	rpsJ	2002167..2002475 (-)	309	WP_011922546.1	30S ribosomal protein S10	-
MU520_RS09810	comX/sigX	2002799..2003065 (-)	267	WP_014635810.1	hypothetical protein	Regulator
MU520_RS09815	-	2003138..2003716 (-)	579	WP_012774895.1	nucleotidyltransferase family protein	-
MU520_RS09820	-	2003924..2004244 (-)	321	WP_002939343.1	DUF1292 domain-containing protein	-
MU520_RS09825	ruvX	2004256..2004675 (-)	420	WP_002939356.1	Holliday junction resolvase RuvX	-
MU520_RS09830	-	2004675..2004941 (-)	267	WP_002939360.1	IreB family regulatory phosphoprotein	-
MU520_RS09835	spx	2005041..2005439 (-)	399	WP_002939362.1	transcriptional regulator Spx	-
MU520_RS09840	recA	2005675..2006826 (-)	1152	WP_011922545.1	recombinase RecA	Machinery gene
MU520_RS09845	cinA	2006878..2008059 (-)	1182	WP_012774894.1	competence/damage-inducible protein A	Machinery gene
MU520_RS09850	-	2008096..2008665 (-)	570	WP_012774893.1	DNA-3-methyladenine glycosylase I	-
MU520_RS09855	ruvA	2009390..2009980 (-)	591	WP_011921679.1	Holliday junction branch migration protein RuvA	-
MU520_RS09860	mutL	2010019..2011956 (-)	1938	WP_012774891.1	DNA mismatch repair endonuclease MutL	-

Sequence

Protein

• Length: 393 a.a.
• Molecular weight: 42862.76 Da
• Isoelectric Point: 4.3975

>NTDB_id=677034 MU520_RS09845 WP_012774894.1 2006878..2008059(-) (cinA) [Streptococcus suis strain TJS56]
MKAELIAVGTEILTGQIINTNAQFLSEKCAELGIDVYFHTAVGDNEGRLLSTLEVASKRSNMVVLCGGLGPTEDDLTKQT
LATFLGRNLVFDELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPLLSQSQQQLYSRVLRFFGIGESQLVTVLADVIDKQTDPTLAPYAKVGEVTLRLSTKATSQEEANLRLNQLEED
ILQHDKLADYFYAYGEDNSLVKTVATRLAEKRQTIAIVEQGTGGLLQAELSLALADQPYFSGGKVVGQLGIESGWLSEEA
DCIRQELQADLGLAVSVLIKPESTEDNVLAKVYLTLATPSGISQKEIDLGGYSWQYLRQLACLQAWDFVRNTL

Nucleotide

• Length: 1182 bp

>NTDB_id=677034 MU520_RS09845 WP_012774894.1 2006878..2008059(-) (cinA) [Streptococcus suis strain TJS56]
ATGAAAGCAGAACTAATCGCCGTTGGGACGGAGATTTTGACAGGTCAAATCATTAATACCAATGCTCAGTTCCTTTCGGA
GAAATGTGCAGAGCTGGGAATTGATGTTTATTTTCATACGGCAGTTGGTGACAATGAAGGCCGTTTATTATCAACCCTTG
AAGTAGCCAGCAAGCGGAGTAATATGGTCGTTCTTTGCGGTGGTTTAGGACCAACTGAGGACGACCTGACCAAGCAGACC
TTGGCGACCTTCTTAGGTAGAAATCTTGTGTTTGATGAGTTGGCTATGGCAAAATTAGACCGTTTCTTTGCCAGTCGCCC
AGGTCGTGTCCGTACACCAAATAATGAACGTCAGGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAATCCAGCTGGTT
TAGCTGTTGGTGGTATGATTGAGCAAGATGGTGTAACCTATATTGTTTTGCCTGGCCCACCAAGTGAGCTCAAGGCCATG
TTTTCTGAGAGTCTCTTACCTTTACTGTCCCAATCTCAGCAGCAACTTTATTCGCGTGTCCTACGCTTTTTTGGAATTGG
CGAAAGCCAGTTGGTGACTGTTTTGGCGGACGTGATTGATAAGCAGACAGACCCAACTCTTGCTCCTTATGCAAAAGTTG
GAGAGGTGACTTTACGCTTGTCCACCAAAGCGACCAGCCAAGAAGAAGCAAATCTACGTTTAAATCAGTTGGAAGAAGAC
ATCTTACAACATGACAAACTGGCAGACTATTTCTATGCCTACGGAGAGGACAATAGTTTGGTCAAAACGGTAGCGACTCG
TTTGGCGGAGAAAAGACAAACCATCGCTATCGTCGAACAGGGGACAGGTGGTCTCTTGCAAGCTGAATTGAGCCTGGCTT
TGGCTGATCAGCCGTATTTTAGCGGAGGAAAAGTCGTCGGTCAGCTAGGGATAGAATCGGGCTGGCTATCAGAGGAAGCT
GACTGCATTCGGCAGGAGCTGCAAGCTGATTTAGGTTTGGCTGTGTCTGTGCTTATCAAACCGGAATCAACAGAGGACAA
CGTACTTGCAAAAGTATACCTCACTTTGGCTACGCCCTCGGGTATTTCCCAAAAAGAGATAGATTTAGGTGGTTATTCGT
GGCAATACCTTCGCCAGCTTGCTTGTCTGCAGGCCTGGGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

• Probable molybdopterin binding domain (MoCF_biosynth) (5-170)

• Competence-damaged protein (CinA) (258-392)

• Damage-inducible protein CinA KH domain (CinA_KH) (178-253)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cinA	Streptococcus suis isolate S10	100	100	1
cinA	Streptococcus pneumoniae R6	54.808	100	0.58
cinA	Streptococcus mitis SK321	54.808	100	0.58
cinA	Streptococcus pneumoniae TIGR4	54.808	100	0.58
cinA	Streptococcus pneumoniae Rx1	54.808	100	0.58
cinA	Streptococcus mutans UA159	55.474	100	0.58
cinA	Streptococcus mitis NCTC 12261	54.567	100	0.578
cinA	Streptococcus pneumoniae D39	54.567	100	0.578
cinA	Bacillus subtilis subsp. subtilis str. 168	41.379	95.929	0.397