Detailed information NTG0676441

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: OHA86_RS17095
• Genome accession: NZ_CP109445
• Coordinates: 4094120..4096726 (-)
• Length: 868 a.a.
• NCBI ID: WP_329176364.1
• Uniprot ID: -
• Organism: Streptomyces sp. NBC_01477
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 4089120..4101726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
OHA86_RS17070 (OHA86_17115)	-	4090184..4090849 (-)	666	WP_329176354.1	ScbR family autoregulator-binding transcription factor	-
OHA86_RS17075 (OHA86_17120)	-	4090954..4091868 (+)	915	WP_329176356.1	ScbA/BarX family gamma-butyrolactone biosynthesis protein	-
OHA86_RS17080 (OHA86_17125)	-	4092081..4092773 (+)	693	WP_329176358.1	HAD family phosphatase	-
OHA86_RS17085 (OHA86_17130)	-	4092905..4093279 (+)	375	WP_329176360.1	VOC family protein	-
OHA86_RS17090 (OHA86_17135)	-	4093469..4094017 (-)	549	WP_329176362.1	YbjN domain-containing protein	-
OHA86_RS17095 (OHA86_17140)	clpE	4094120..4096726 (-)	2607	WP_329176364.1	ATP-dependent chaperone ClpB	Regulator
OHA86_RS17100 (OHA86_17145)	-	4096975..4097382 (+)	408	WP_329176366.1	TIGR03618 family F420-dependent PPOX class oxidoreductase	-
OHA86_RS17105 (OHA86_17150)	-	4097513..4097986 (-)	474	WP_329182444.1	helix-turn-helix domain-containing protein	-
OHA86_RS17110 (OHA86_17155)	dnaJ	4098009..4099208 (-)	1200	WP_329176367.1	molecular chaperone DnaJ	-
OHA86_RS17115 (OHA86_17160)	grpE	4099244..4099918 (-)	675	WP_329176369.1	nucleotide exchange factor GrpE	-

Sequence

Protein

• Length: 868 a.a.
• Molecular weight: 94654.08 Da
• Isoelectric Point: 4.7956

>NTDB_id=676441 OHA86_RS17095 WP_329176364.1 4094120..4096726(-) (clpE) [Streptomyces sp. NBC_01477]
MDAELTNKSREALNAANTRAVSEGNPDLTPAHLLLALLSGTDNENVLDLLTAVGADPAAVTAQAGRLVEGLPKVQGSTVA
PPQANRDLLAVIADAAERAKELGDAYLSTEHLLIGIAVKGGPAGDLLTRQGAGGKELLTAFETARGGQRVTSQDPEGTYK
ALEKYGTDFTAAAREGRLDPVIGRDQEIRRVVQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQRIVKGDVPESLRDKRLVS
LDLGAMVAGAKYRGEFEERLKSVLAEIKDSDGRVITFIDELHTVVGAGAGGDSAMDAGNMLKPMLARGELRMVGATTLDE
YRERIEKDPALERRFQQVLVAEPTVEDTVAILRGLKGRYEAHHKVQIADSALVAAATLSDRYITSRFLPDKAIDLVDESA
SRLRMEIDSSPVEIDELQRSVDRLRMEEMAVKNDTDPRAVQRLVKLRKDLADREEELRGLTARWEKEKQGLNRVGELKER
LDDIGTRIDRAQRDGDFETASKLLYAEKPKLEAELAEATREEQEAAGQETMVKEQVGPDDIADVVAAWTGIPAGRLLEGE
TQKLLRMEEELGRRLIGQTEAVRAVSDAVRRSRSGIADPDRPTGSFLFLGPTGVGKTELAKALADFLFDDERAMVRIDMS
EYGEKHSVARLVGAPPGYVGYEEGGQLTEAVRRRPYSVILLDEVEKAHPEVFDVLLQVLDDGRLTDGQGRTVDFRNTILI
LTSNLGSQYLVDPALSDEQKREHVLSTVRAAFKPEFLNRLDDIVVFSALAKDELRRIARLQTDRLAARLRDRRLALDITD
EALDWLADEGNDPAYGARPLRRLVQTAIGDPLARALLAGEVADGQTVRVDRAADGLIVGAASGPDLSK

Nucleotide

• Length: 2607 bp

>NTDB_id=676441 OHA86_RS17095 WP_329176364.1 4094120..4096726(-) (clpE) [Streptomyces sp. NBC_01477]
GTGGACGCCGAGCTGACCAACAAGAGCCGGGAAGCGCTCAACGCCGCCAACACCCGGGCGGTCTCCGAGGGCAACCCGGA
CCTGACGCCCGCGCATCTGCTGCTCGCACTGCTGAGCGGCACGGACAACGAGAACGTGCTCGACCTGCTCACCGCGGTCG
GCGCCGACCCGGCGGCCGTCACGGCGCAAGCCGGCCGGCTGGTCGAGGGGCTGCCGAAGGTGCAGGGCTCCACCGTGGCG
CCGCCGCAGGCCAACCGCGACCTGCTCGCGGTGATCGCGGACGCCGCCGAGCGGGCCAAGGAGCTGGGGGACGCGTACCT
TTCCACCGAGCACCTGCTGATCGGGATCGCCGTCAAGGGCGGCCCGGCCGGTGACCTGCTCACCCGTCAGGGGGCCGGCG
GCAAGGAGCTGCTGACCGCCTTCGAGACCGCCCGTGGGGGGCAGCGCGTGACCAGCCAGGATCCCGAGGGCACGTACAAG
GCGCTGGAGAAGTACGGCACCGACTTCACCGCGGCGGCCCGCGAGGGCAGGCTCGACCCGGTGATCGGCCGCGACCAGGA
GATCCGCCGGGTCGTCCAGGTGCTCTCCCGGCGCACCAAGAACAACCCGGTGCTCATCGGCGAGCCCGGCGTCGGCAAGA
CCGCGGTCGTCGAGGGCCTGGCCCAGCGCATCGTCAAGGGCGACGTGCCCGAGTCGCTGCGCGACAAGCGGCTGGTCTCG
CTCGACCTCGGCGCGATGGTCGCCGGCGCCAAATACCGCGGCGAGTTCGAGGAACGGCTCAAGTCGGTGCTCGCCGAGAT
CAAGGACAGCGACGGCCGCGTCATCACCTTCATCGACGAGCTGCACACCGTGGTCGGCGCGGGCGCCGGCGGTGACTCGG
CCATGGACGCGGGGAACATGCTCAAGCCGATGCTGGCCCGCGGTGAACTGCGGATGGTCGGCGCGACCACGCTGGACGAG
TACCGCGAGCGGATCGAGAAGGACCCGGCCCTGGAGCGCCGCTTCCAGCAGGTGCTGGTCGCCGAGCCGACCGTCGAGGA
CACGGTGGCGATCCTGCGCGGCCTCAAGGGCCGCTACGAGGCCCACCACAAGGTGCAGATCGCCGACTCCGCGCTGGTCG
CCGCGGCGACGCTGTCCGACCGCTACATCACCTCGCGCTTCCTGCCCGACAAGGCCATCGACCTGGTGGACGAGTCGGCG
TCCCGGCTGCGGATGGAGATCGACTCCTCGCCGGTCGAGATCGACGAGCTGCAGCGCTCGGTCGACCGGCTGCGCATGGA
GGAGATGGCGGTCAAGAACGACACCGACCCCCGCGCCGTGCAGCGCCTGGTCAAGCTGCGCAAGGACCTCGCCGACCGCG
AGGAGGAGCTGCGCGGCCTGACCGCCCGCTGGGAGAAGGAGAAGCAGGGCCTGAACCGGGTCGGTGAGCTGAAGGAGCGG
CTCGACGACATCGGGACCCGGATCGACCGCGCCCAGCGCGACGGCGACTTCGAGACCGCCTCCAAGCTGCTCTACGCCGA
GAAGCCCAAGCTGGAGGCCGAGCTGGCGGAGGCCACCCGCGAGGAGCAGGAGGCCGCGGGCCAGGAGACGATGGTCAAGG
AGCAGGTCGGCCCGGACGACATCGCCGACGTCGTCGCCGCCTGGACCGGCATCCCGGCCGGCCGGCTGCTGGAGGGCGAG
ACGCAGAAGCTGCTGCGGATGGAGGAGGAGCTGGGCCGCCGGCTGATCGGCCAGACCGAGGCGGTCCGCGCGGTCTCCGA
CGCCGTACGCCGCTCCCGCTCCGGTATCGCCGACCCCGACCGCCCGACCGGCTCCTTCCTCTTCCTGGGCCCGACCGGTG
TCGGCAAGACCGAGCTGGCCAAGGCGCTGGCCGACTTCCTCTTCGACGACGAGCGGGCCATGGTCCGTATCGACATGAGC
GAATACGGCGAGAAGCACTCGGTGGCCCGGCTGGTCGGCGCGCCTCCCGGCTACGTGGGGTACGAGGAGGGCGGCCAGCT
CACCGAGGCGGTGCGCCGCCGCCCGTACAGCGTGATCCTGCTGGACGAGGTCGAGAAGGCGCACCCCGAGGTCTTCGACG
TGCTGCTCCAGGTGCTGGACGACGGGCGGCTCACCGACGGCCAGGGCCGTACGGTCGACTTCCGCAACACCATCCTCATC
CTGACCTCGAACCTCGGCAGCCAGTATCTGGTGGACCCGGCGCTGAGCGACGAGCAGAAGCGCGAGCACGTGCTGAGCAC
GGTCCGCGCCGCCTTCAAGCCGGAGTTCCTCAACCGGCTGGACGACATCGTGGTCTTCTCCGCGCTGGCCAAGGACGAGC
TGCGCAGGATCGCCCGGCTGCAGACCGACCGGCTCGCCGCCAGGCTGCGGGACCGCAGGCTCGCCCTCGACATCACCGAC
GAGGCCCTGGACTGGCTCGCCGACGAGGGCAACGACCCGGCCTACGGCGCCCGGCCGCTGCGCCGCCTGGTGCAGACCGC
CATCGGCGACCCGCTGGCCCGCGCCCTGCTGGCGGGCGAGGTCGCCGACGGGCAGACGGTGCGGGTGGACCGCGCCGCCG
ACGGGCTGATCGTGGGTGCGGCGAGCGGTCCCGACCTCAGCAAATGA

Domains

Predicted by InterProScan.

• ATPase family associated with various cellular activities (AAA) (AAA) (204-338)

• AAA domain (Cdc48 subfamily) (AAA_2) (601-763)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (769-849)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (18-64)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (95-146)

• AAA lid domain (AAA_lid_9) (344-445)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.083	82.949	0.391
clpE	Streptococcus pneumoniae TIGR4	47.353	78.341	0.371
clpE	Streptococcus pneumoniae Rx1	47.353	78.341	0.371
clpE	Streptococcus pneumoniae D39	47.353	78.341	0.371
clpE	Streptococcus pneumoniae R6	47.353	78.341	0.371
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	45.092	80.991	0.365
clpC	Lactococcus lactis subsp. cremoris KW2	45.231	79.724	0.361