Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   MP619_RS11075 Genome accession   NZ_CP095081
Coordinates   2232045..2233316 (-) Length   423 a.a.
NCBI ID   WP_129556361.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae strain WJ001     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 2227045..2238316
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MP619_RS11045 (MP619_11015) - 2227165..2228727 (-) 1563 WP_129556360.1 DUF2079 domain-containing protein -
  MP619_RS11050 (MP619_11020) - 2229064..2229369 (-) 306 WP_003045716.1 DUF1292 domain-containing protein -
  MP619_RS11055 (MP619_11025) ruvX 2229380..2229799 (-) 420 WP_003053103.1 Holliday junction resolvase RuvX -
  MP619_RS11060 (MP619_11030) - 2229796..2230065 (-) 270 WP_003045720.1 IreB family regulatory phosphoprotein -
  MP619_RS11065 (MP619_11035) spx 2230177..2230575 (-) 399 WP_003053105.1 transcriptional regulator Spx -
  MP619_RS11070 (MP619_11040) recA 2230804..2231940 (-) 1137 WP_003058758.1 recombinase RecA Machinery gene
  MP619_RS11075 (MP619_11045) cinA 2232045..2233316 (-) 1272 WP_129556361.1 competence/damage-inducible protein A Machinery gene
  MP619_RS11080 (MP619_11050) - 2233440..2233793 (-) 354 WP_003058738.1 VOC family protein -
  MP619_RS11085 (MP619_11055) - 2233796..2234368 (-) 573 WP_129556362.1 DNA-3-methyladenine glycosylase I -
  MP619_RS11090 (MP619_11060) ruvA 2234378..2234971 (-) 594 WP_129556363.1 Holliday junction branch migration protein RuvA -
  MP619_RS11095 (MP619_11065) - 2234973..2236193 (-) 1221 WP_268227778.1 MFS transporter -
  MP619_RS11100 (MP619_11070) mutL 2236204..2238186 (-) 1983 WP_129556417.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46029.52 Da        Isoelectric Point: 4.7069

>NTDB_id=675121 MP619_RS11075 WP_129556361.1 2232045..2233316(-) (cinA) [Streptococcus dysgalactiae strain WJ001]
MKAELITVGTEILTGQIVNTNAQFLSEKMAELGIDVYFQTAVGDNEERLLSVIATASQRSDLVILCGGLGPTEDDLTKQT
LAKYLNRDLVFEEQASQKLDDFYASRKESSRTANNAKQAQIIAGSSPLQNRTGLAVGGLITVNEVTYVVLPGPPSELKPM
VNEELLPLLSTQSRKLYSRVLRFFGIGESQLVTVLSDLIENQTDPTIAPYAKTGEVTLRLSTKAENQTLADTKLDPLEAQ
LLSRKTPDNQSLSDFLYGYREDNSLAREVFELLVKYDKTITAAESLTAGLFQSTLASFPGASQVFNGGFVTYSMEEKAKM
LGIPLEDLILHGVVSAYTAEKMAEQTRLLTGADIGVSLTGVAGPDMLEDQPAGTVFIGLATQNKVESMKVLIGGRSRSDV
RHIATLHAFNMVRKTLLKPENLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=675121 MP619_RS11075 WP_129556361.1 2232045..2233316(-) (cinA) [Streptococcus dysgalactiae strain WJ001]
ATGAAAGCTGAACTGATTACAGTAGGTACCGAAATTTTGACTGGTCAAATTGTGAATACCAATGCTCAATTTCTGTCGGA
AAAAATGGCAGAGCTAGGTATTGATGTCTATTTTCAAACGGCTGTTGGGGATAACGAGGAGCGTTTACTTTCAGTGATTG
CAACTGCTAGTCAGCGGAGTGATTTGGTCATTTTATGCGGTGGTCTTGGCCCCACGGAAGATGATTTAACCAAGCAGACT
TTAGCAAAATATCTTAATAGAGATTTGGTCTTTGAAGAACAAGCTAGTCAAAAATTGGACGACTTTTATGCTAGTCGTAA
AGAGTCGTCTCGAACGGCAAATAATGCTAAGCAGGCTCAAATCATTGCTGGTTCAAGCCCTCTGCAAAATAGAACAGGAC
TTGCAGTGGGTGGCTTAATCACTGTTAATGAGGTGACTTATGTTGTTTTACCCGGGCCGCCAAGTGAATTAAAACCTATG
GTTAATGAGGAACTGCTTCCTCTTTTGTCCACACAATCTCGCAAACTTTATTCGAGAGTTTTACGATTTTTTGGGATTGG
TGAGAGTCAGCTGGTGACGGTCTTATCAGACCTTATTGAGAATCAAACTGACCCTACCATTGCACCCTATGCCAAAACTG
GTGAAGTGACCCTTCGTTTATCAACGAAAGCTGAAAATCAAACATTAGCAGATACGAAATTAGATCCACTAGAAGCGCAG
CTATTGTCGCGAAAAACTCCTGACAACCAGTCGTTATCAGATTTTCTTTATGGCTATAGGGAGGATAATTCCTTAGCGCG
TGAGGTATTTGAGCTCTTAGTAAAATATGATAAGACAATTACAGCAGCAGAAAGTCTAACCGCGGGATTATTTCAGTCAA
CTTTGGCGAGTTTTCCAGGAGCTTCTCAAGTATTCAATGGAGGCTTTGTAACTTATAGCATGGAAGAAAAAGCGAAAATG
CTAGGCATTCCTTTAGAGGATTTGATATTGCATGGAGTTGTTAGTGCCTATACGGCCGAGAAGATGGCGGAGCAAACAAG
GTTATTGACTGGTGCTGATATTGGGGTAAGTTTAACAGGTGTTGCCGGACCAGATATGTTGGAGGACCAGCCTGCAGGTA
CAGTTTTCATTGGCCTTGCCACTCAAAATAAGGTAGAATCAATGAAGGTTTTAATCGGGGGACGGAGCCGTTCAGATGTG
CGTCATATTGCGACTTTACATGCTTTTAACATGGTCCGTAAAACTTTATTAAAACCTGAAAATTTGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-243)

Competence-damaged protein (CinA)

(263-416)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

72.577

100

0.726
  cinA Streptococcus mitis SK321

70.743

98.582

0.697
  cinA Streptococcus mitis NCTC 12261

69.784

98.582

0.688
  cinA Streptococcus pneumoniae TIGR4

69.065

98.582

0.681
  cinA Streptococcus pneumoniae Rx1

69.065

98.582

0.681
  cinA Streptococcus pneumoniae R6

69.065

98.582

0.681
  cinA Streptococcus pneumoniae D39

68.825

98.582

0.678
  cinA Streptococcus suis isolate S10

53.365

98.345

0.525
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

98.818

0.452