Detailed information NTG0672941

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: MUA71_RS05375
• Genome accession: NZ_CP094806
• Coordinates: 1102723..1103766 (+)
• Length: 347 a.a.
• NCBI ID: WP_002509180.1
• Uniprot ID: A0A7V7SQH4
• Organism: Staphylococcus arlettae strain IVB6234
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1097723..1108766

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MUA71_RS05350 (MUA71_05315)	-	1098399..1099124 (+)	726	WP_002509175.1	type 1 glutamine amidotransferase	-
MUA71_RS05355 (MUA71_05320)	-	1099615..1100601 (-)	987	WP_142019532.1	aromatic acid exporter family protein	-
MUA71_RS05360 (MUA71_05325)	map	1100767..1101519 (+)	753	WP_002509177.1	type I methionyl aminopeptidase	-
MUA71_RS05365 (MUA71_05330)	-	1101622..1102008 (+)	387	WP_002509178.1	hypothetical protein	-
MUA71_RS05370 (MUA71_05335)	liaF	1102025..1102726 (+)	702	WP_002509179.1	cell wall-active antibiotics response protein LiaF	-
MUA71_RS05375 (MUA71_05340)	vraS	1102723..1103766 (+)	1044	WP_002509180.1	sensor histidine kinase	Regulator
MUA71_RS05380 (MUA71_05345)	vraR	1103756..1104385 (+)	630	WP_002509181.1	response regulator transcription factor	Regulator
MUA71_RS05385 (MUA71_05350)	-	1104446..1105525 (-)	1080	WP_142019533.1	YihY/virulence factor BrkB family protein	-
MUA71_RS05390 (MUA71_05355)	-	1105805..1106089 (-)	285	WP_002509183.1	hypothetical protein	-
MUA71_RS05395 (MUA71_05360)	-	1106096..1106560 (-)	465	WP_002509184.1	low molecular weight protein-tyrosine-phosphatase	-
MUA71_RS05400 (MUA71_05365)	-	1106696..1106899 (+)	204	WP_142019535.1	DUF1128 family protein	-
MUA71_RS05405 (MUA71_05370)	-	1106911..1108149 (+)	1239	WP_112369296.1	aminopeptidase	-
MUA71_RS05410 (MUA71_05375)	-	1108189..1108710 (+)	522	WP_002509187.1	acyl-CoA thioesterase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39859.16 Da
• Isoelectric Point: 5.2631

>NTDB_id=672941 MUA71_RS05375 WP_002509180.1 1102723..1103766(+) (vraS) [Staphylococcus arlettae strain IVB6234]
MNHYIRAIGSMLILVYSTLIAFFFIDKIFVNIMYFQGMFYTQIFGIPVFLFLNLLIILLCIIVGSVLAYKINQQNHWLQT
QIERSIEGETVGINDQDIELYNETIELYQTLVPLNQEVHKLRMKTQNLTNESYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKESQLTPPLDQQIPTLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVVDLQKKVPMKVIHDI
EDFTVPKGIEDHLFRITQEAISNTLRHSNGTKVTIELFNQEAYLLLRIQDNGIGFNVDDKAEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLDKEDIDAN

Nucleotide

• Length: 1044 bp

>NTDB_id=672941 MUA71_RS05375 WP_002509180.1 1102723..1103766(+) (vraS) [Staphylococcus arlettae strain IVB6234]
ATGAATCACTACATTAGAGCAATAGGCTCTATGCTAATATTAGTATATAGTACATTAATTGCTTTTTTCTTTATAGATAA
AATATTTGTAAATATTATGTATTTTCAAGGTATGTTTTATACCCAAATATTTGGTATTCCAGTATTTTTATTTTTAAATT
TGCTCATAATTTTATTATGTATCATTGTAGGATCGGTTTTAGCTTATAAAATAAACCAGCAAAACCATTGGCTACAAACA
CAAATTGAACGTTCAATTGAAGGAGAAACAGTAGGGATTAATGACCAAGATATAGAACTTTATAATGAAACTATAGAGCT
CTATCAAACGTTAGTTCCACTCAATCAAGAAGTACATAAACTGCGAATGAAGACCCAAAATTTAACAAATGAATCTTATA
ATTTAAACGATGTCAAAGTTAAAAAAATAATCGAAGATGAACGACAAAGATTGGCTAGGGAATTACATGATTCAGTGAGT
CAGCAACTTTTTGCAGCTAGCATGATGTTATCAGCTATCAAAGAATCCCAATTAACACCACCGTTAGATCAACAAATCCC
TACATTAGAAAAAATGGTACAAGATTCTCAACTAGAAATGAGAGCATTATTACTACATTTAAGACCAATTGGTTTAAAAG
ATAAGTCTCTCGGCGAAGGTATTAAAGATTTAGTTGTCGATTTACAGAAAAAAGTACCAATGAAGGTCATACATGATATT
GAAGATTTTACTGTACCTAAAGGTATTGAAGATCATTTGTTTCGTATTACGCAAGAAGCGATATCCAATACATTACGTCA
TTCCAACGGTACAAAAGTAACAATTGAATTATTTAATCAAGAAGCATATTTATTATTACGTATTCAAGATAACGGTATTG
GTTTTAACGTAGATGATAAAGCTGAACAAAGTTATGGATTGAAAAATATGCGGGAGCGTGCATTAGAAATAGGTGCCACA
TTCCATATTGTATCGCTGCCTGATTCAGGTACTAGAATAGAAGTGAAAGCACCATTAGATAAGGAGGATATAGATGCCAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

3D structure

• AlphaFold DB: A0A7V7SQH4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	88.63	98.847	0.876