Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SITYG_RS09715 Genome accession   NZ_AP014880
Coordinates   1899335..1900603 (-) Length   422 a.a.
NCBI ID   WP_096363248.1    Uniprot ID   A0AAD1CA15
Organism   Streptococcus intermedius strain TYG1620     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1894335..1905603
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SITYG_RS09685 (SITYG_19060) - 1895056..1895361 (-) 306 WP_003075274.1 DUF1292 domain-containing protein -
  SITYG_RS09690 (SITYG_19070) ruvX 1895379..1895798 (-) 420 WP_003075276.1 Holliday junction resolvase RuvX -
  SITYG_RS09695 (SITYG_19080) - 1895798..1896064 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  SITYG_RS09700 (SITYG_19090) - 1896370..1896927 (-) 558 WP_020999236.1 SP0191 family lipoprotein -
  SITYG_RS10770 (SITYG_19100) - 1897441..1897575 (-) 135 WP_269457668.1 hypothetical protein -
  SITYG_RS09705 (SITYG_19110) spx 1897657..1898055 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  SITYG_RS09710 (SITYG_19120) recA 1898141..1899286 (-) 1146 WP_003077215.1 recombinase RecA Machinery gene
  SITYG_RS09715 (SITYG_19130) cinA 1899335..1900603 (-) 1269 WP_096363248.1 competence/damage-inducible protein A Machinery gene
  SITYG_RS09720 (SITYG_19140) - 1900739..1900912 (-) 174 Protein_1875 CPBP family intramembrane glutamate endopeptidase -
  SITYG_RS09725 (SITYG_19150) - 1900917..1901471 (-) 555 WP_096363249.1 DNA-3-methyladenine glycosylase I -
  SITYG_RS09730 (SITYG_19160) ruvA 1901481..1902071 (-) 591 WP_096363250.1 Holliday junction branch migration protein RuvA -
  SITYG_RS09735 (SITYG_19170) - 1902241..1902747 (+) 507 WP_096363251.1 helix-turn-helix domain-containing protein -
  SITYG_RS09740 (SITYG_19180) - 1902731..1903240 (+) 510 WP_162287173.1 RDD family protein -
  SITYG_RS09745 (SITYG_19190) mutL 1903386..1905332 (-) 1947 WP_021003321.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45567.10 Da        Isoelectric Point: 6.3717

>NTDB_id=67291 SITYG_RS09715 WP_096363248.1 1899335..1900603(-) (cinA) [Streptococcus intermedius strain TYG1620]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAGLGVDVYFQTAVGDNEDRLLSILEIARDRSNLVILTGGLGPTEDDLTKQT
LSKFLNRRLVFHQVAVEKLNRFFSSRPDYTRTPNNERQAQIVEGATPLRNETGLAVGGVVEVSGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGNLIDTQTDPTIAPYAKTGEVTLRLSTKASSQKEADVKFAHLEKKI
LAVQTFEKQQLADLFYAYGDDNSLGQTAFELLKKAGKTVTAAESLTAGLFQATLANFSGASKVFGGGFVTYGIEEKSQML
GIPLADLEMHGVVSAYTAEKMATQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATADNVQSIQVNIAERSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=67291 SITYG_RS09715 WP_096363248.1 1899335..1900603(-) (cinA) [Streptococcus intermedius strain TYG1620]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAGATTTTGACTGGTCAGATTGTCAATACGAATGCTCAATTTTTATCTGA
AAAATTAGCGGGCTTGGGAGTAGATGTCTATTTCCAGACAGCGGTTGGAGATAATGAAGATCGTCTGTTATCCATTTTAG
AAATAGCTAGAGATCGTAGTAATTTAGTTATCTTGACAGGTGGTTTAGGTCCGACTGAAGACGACTTAACCAAGCAGACT
TTGTCAAAATTTTTGAATCGTAGGCTAGTCTTTCATCAAGTAGCTGTTGAAAAATTGAATCGTTTCTTCTCCAGCCGACC
GGACTATACTCGAACACCAAATAATGAGCGACAAGCTCAGATAGTAGAAGGGGCGACTCCTCTACGAAATGAAACCGGAC
TTGCAGTTGGTGGCGTTGTTGAAGTCAGTGGTGTGACTTATGTTGTTCTACCTGGCCCCCCTAGTGAACTAAAGCCTATG
GTAAACAATGAGTTGGTTCCGCTTTTAGCAACTGGCCAAAAATTGTATTCGAGAGTCTTGCGTTTCTTTGGTATTGGGGA
GAGTCAATTAGTCACCCTTTTAGGAAACTTGATTGATACTCAGACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTGACGTTGCGATTGTCGACCAAGGCCAGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATCTGGAAAAGAAAATT
TTAGCAGTACAGACTTTTGAGAAACAACAATTAGCCGACCTTTTCTATGCTTATGGAGATGACAATTCTCTGGGACAGAC
AGCTTTTGAATTGTTGAAGAAAGCAGGCAAAACAGTCACAGCAGCTGAAAGTCTGACTGCGGGACTTTTTCAAGCGACTT
TAGCAAATTTTTCTGGAGCGTCCAAGGTCTTTGGAGGTGGCTTTGTTACTTATGGCATAGAGGAGAAGAGTCAAATGTTA
GGCATTCCATTGGCAGATTTAGAAATGCATGGGGTAGTCTCAGCTTATACAGCAGAGAAAATGGCTACGCAAGCTAGGAA
ATTGACTGCTAGTGACTATGCGGTGAGTTTGACTGGAGTAGCAGGTCCAGATAGTTTAGAAGGCCATCCAGCAGGAACTG
TTTATATTGGCTTGGCAACTGCAGATAACGTTCAGTCTATTCAGGTTAATATTGCGGAGCGCAGTCGGACGGATGTACGT
AAAATAGCTGTGTTACATGCTTTCAATTTGTTGCGAAAAACTTTATTAAAAAATGAGAATATGCTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Competence-damaged protein (CinA)

(263-415)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

75.12

99.052

0.744
  cinA Streptococcus mitis NCTC 12261

73.684

99.052

0.73
  cinA Streptococcus pneumoniae TIGR4

73.684

99.052

0.73
  cinA Streptococcus pneumoniae Rx1

73.445

99.052

0.727
  cinA Streptococcus pneumoniae R6

73.445

99.052

0.727
  cinA Streptococcus pneumoniae D39

73.206

99.052

0.725
  cinA Streptococcus mutans UA159

70.449

100

0.706
  cinA Streptococcus suis isolate S10

53.606

98.578

0.528
  cinA Bacillus subtilis subsp. subtilis str. 168

45.933

99.052

0.455

Multiple sequence alignment