Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   SRT_RS01080 Genome accession   NZ_AP014612
Coordinates   212094..213125 (+) Length   343 a.a.
NCBI ID   WP_256376016.1    Uniprot ID   -
Organism   Streptococcus troglodytae strain TKU 31     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 207094..218125
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS01070 (SRT_01910) - 210708..211091 (+) 384 WP_128832748.1 DUF1033 family protein -
  SRT_RS01075 comGA 211219..212158 (+) 940 Protein_179 competence type IV pilus ATPase ComGA -
  SRT_RS01080 (SRT_01940) comYB 212094..213125 (+) 1032 WP_256376016.1 competence type IV pilus assembly protein ComGB Machinery gene
  SRT_RS01085 (SRT_01950) comYC 213125..213439 (+) 315 WP_128832750.1 competence type IV pilus major pilin ComGC Machinery gene
  SRT_RS01090 (SRT_01960) comYD 213426..213830 (+) 405 WP_161940061.1 competence type IV pilus minor pilin ComGD Machinery gene
  SRT_RS01095 (SRT_01970) comYE 213802..214095 (+) 294 WP_128832752.1 competence type IV pilus minor pilin ComGE Machinery gene
  SRT_RS01100 (SRT_01980) comYF 214082..214516 (+) 435 WP_128832753.1 competence type IV pilus minor pilin ComGF Machinery gene
  SRT_RS01105 (SRT_01990) comYG 214494..214883 (+) 390 WP_128832754.1 competence type IV pilus minor pilin ComGG Machinery gene
  SRT_RS01110 (SRT_02010) - 214938..215890 (+) 953 Protein_186 class I SAM-dependent methyltransferase -
  SRT_RS01115 (SRT_02020) - 215949..217148 (+) 1200 WP_128832755.1 acetate kinase -
  SRT_RS01120 (SRT_02040) - 217692..217892 (+) 201 WP_128834002.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 343 a.a.        Molecular weight: 39773.42 Da        Isoelectric Point: 9.5097

>NTDB_id=66152 SRT_RS01080 WP_256376016.1 212094..213125(+) (comYB) [Streptococcus troglodytae strain TKU 31]
MTFLQQDILLKEKHKQKKLKIKKQRKVIQLFNNLFTSGFNLTEIIDFLERSHLLAEVYTKKMRQGLLSGLHLAEIMSSLG
FSDDVVTQLALSEIHGNTQKSLLKIESYLNNLILVKKKLVEVITYPIILLIFLVVIMLGLKNYLLPQLEKGNFATRLISN
FPTLFLLGCCFFILLVGIFAFFSRKLSRLHLIGFCSHLPFAGKYLQLYLTAYYAREWGNLIGQGVEMAQIVRLMQDQKSQ
LFREIGYDMEKALLSGQEFHQKVLDYPFFLKELSLMIEYGEVKSKLGNELEIYAEETWEHFFAKLKKATQFVQPLIFVFV
AIVIVMIYAAMLLPIYQNMEVNL

Nucleotide


Download         Length: 1032 bp        

>NTDB_id=66152 SRT_RS01080 WP_256376016.1 212094..213125(+) (comYB) [Streptococcus troglodytae strain TKU 31]
ATGACCTTTTTACAGCAGGATATATTACTGAAGGAGAAGCACAAGCAGAAGAAATTGAAGATTAAAAAGCAAAGAAAAGT
TATTCAGCTTTTTAATAATCTCTTTACTAGTGGTTTTAATTTAACAGAAATTATAGATTTTTTAGAACGAAGTCACTTGT
TAGCAGAAGTATACACAAAGAAAATGCGCCAAGGGTTGTTGAGTGGTCTGCATTTGGCTGAAATAATGAGTTCTTTGGGA
TTCTCAGATGATGTTGTTACTCAATTAGCACTTTCTGAAATTCATGGAAACACTCAAAAAAGTCTTTTAAAGATTGAATC
CTATCTAAATAACCTGATACTTGTTAAAAAGAAATTAGTTGAGGTTATCACTTATCCAATCATTTTATTGATTTTTCTTG
TCGTTATTATGTTGGGATTAAAGAATTATTTATTACCACAACTTGAAAAAGGGAATTTTGCAACTCGGTTGATTTCTAAT
TTTCCAACACTTTTCTTGCTGGGCTGTTGCTTTTTTATTTTGCTAGTTGGTATTTTTGCTTTCTTTTCACGAAAACTCAG
TCGTCTGCATTTAATTGGTTTTTGCAGCCATTTGCCTTTTGCTGGTAAGTATTTGCAACTTTATTTAACAGCTTATTATG
CGCGTGAATGGGGTAATCTTATTGGGCAAGGAGTAGAAATGGCTCAGATAGTTAGATTGATGCAAGATCAAAAGTCACAG
CTTTTTAGAGAAATTGGCTATGATATGGAGAAGGCCTTGCTATCAGGTCAAGAGTTTCATCAAAAAGTTTTAGATTATCC
TTTCTTTTTAAAAGAACTCAGTCTTATGATTGAATATGGAGAAGTAAAGTCAAAATTGGGAAATGAATTGGAAATTTATG
CTGAGGAAACATGGGAACACTTTTTTGCGAAGTTAAAAAAAGCAACACAGTTTGTTCAGCCACTCATCTTTGTTTTTGTA
GCTATTGTTATTGTTATGATTTATGCAGCCATGCTTTTGCCAATTTATCAGAATATGGAGGTTAATTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(29-146)

Type II secretion system (T2SS), protein F (T2SSF)

(214-334)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA159

97.668

100

0.977
  comYB Streptococcus mutans UA140

97.668

100

0.977
  comYB Streptococcus gordonii str. Challis substr. CH1

59.767

100

0.598
  comGB/cglB Streptococcus mitis NCTC 12261

57.927

95.627

0.554
  comGB/cglB Streptococcus mitis SK321

56.707

95.627

0.542
  comGB/cglB Streptococcus pneumoniae Rx1

56.098

95.627

0.536
  comGB/cglB Streptococcus pneumoniae D39

56.098

95.627

0.536
  comGB/cglB Streptococcus pneumoniae R6

56.098

95.627

0.536
  comGB/cglB Streptococcus pneumoniae TIGR4

56.098

95.627

0.536
  comGB Lactococcus lactis subsp. cremoris KW2

51.929

98.251

0.51

Multiple sequence alignment