Detailed information NTG0066156

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: SRT_RS01100
• Genome accession: NZ_AP014612
• Coordinates: 214082..214516 (+)
• Length: 144 a.a.
• NCBI ID: WP_128832753.1
• Uniprot ID: A0A1L7LH56
• Organism: Streptococcus troglodytae strain TKU 31
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 209082..219516

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SRT_RS01070 (SRT_01910)	-	210708..211091 (+)	384	WP_128832748.1	DUF1033 family protein	-
SRT_RS01075	comGA	211219..212158 (+)	940	Protein_179	competence type IV pilus ATPase ComGA	-
SRT_RS01080 (SRT_01940)	comYB	212094..213125 (+)	1032	WP_256376016.1	competence type IV pilus assembly protein ComGB	Machinery gene
SRT_RS01085 (SRT_01950)	comYC	213125..213439 (+)	315	WP_128832750.1	competence type IV pilus major pilin ComGC	Machinery gene
SRT_RS01090 (SRT_01960)	comYD	213426..213830 (+)	405	WP_161940061.1	competence type IV pilus minor pilin ComGD	Machinery gene
SRT_RS01095 (SRT_01970)	comYE	213802..214095 (+)	294	WP_128832752.1	competence type IV pilus minor pilin ComGE	Machinery gene
SRT_RS01100 (SRT_01980)	comYF	214082..214516 (+)	435	WP_128832753.1	competence type IV pilus minor pilin ComGF	Machinery gene
SRT_RS01105 (SRT_01990)	comYG	214494..214883 (+)	390	WP_128832754.1	competence type IV pilus minor pilin ComGG	Machinery gene
SRT_RS01110 (SRT_02010)	-	214938..215890 (+)	953	Protein_186	class I SAM-dependent methyltransferase	-
SRT_RS01115 (SRT_02020)	-	215949..217148 (+)	1200	WP_128832755.1	acetate kinase	-
SRT_RS01120 (SRT_02040)	-	217692..217892 (+)	201	WP_128834002.1	helix-turn-helix transcriptional regulator	-
SRT_RS01125 (SRT_02050)	-	217906..218345 (+)	440	Protein_189	hypothetical protein	-
SRT_RS01130 (SRT_02060)	-	218397..219059 (+)	663	WP_128832757.1	type II CAAX endopeptidase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16239.74 Da
• Isoelectric Point: 9.8105

>NTDB_id=66156 SRT_RS01100 WP_128832753.1 214082..214516(+) (comYF) [Streptococcus troglodytae strain TKU 31]
MLKSKLKAFTLLECLLALLVIAGSVSVYNGLTKAISSNIHYLSENQEDAWLLFCQQFRSELEGTTLQKLDSNKLYIQKNN
QSLAFGKSKVSDFRKTNSDGRGYQPMLMGIKAANFSQSGKIIKLDVTFKDGLERTFVYAFHEKN

Nucleotide

• Length: 435 bp

>NTDB_id=66156 SRT_RS01100 WP_128832753.1 214082..214516(+) (comYF) [Streptococcus troglodytae strain TKU 31]
TTGTTAAAAAGTAAATTGAAAGCTTTCACACTTTTAGAGTGTCTTCTTGCTTTGCTTGTAATTGCTGGTAGTGTATCTGT
TTATAATGGTCTAACTAAAGCTATTAGTAGTAATATTCATTATTTATCAGAAAATCAAGAGGATGCTTGGTTACTTTTTT
GTCAGCAATTTCGGTCTGAACTTGAAGGAACGACTTTGCAAAAATTAGATAGCAATAAGCTTTATATTCAAAAAAATAAT
CAAAGTTTAGCATTTGGTAAATCAAAAGTAAGTGATTTTAGAAAAACTAACAGTGATGGACGTGGTTATCAGCCTATGTT
GATGGGGATCAAAGCTGCTAATTTTAGTCAATCAGGAAAAATTATTAAATTAGACGTTACTTTCAAAGATGGTTTAGAGA
GGACTTTTGTTTATGCTTTTCATGAAAAAAATTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (37-133)

3D structure

• AlphaFold DB: A0A1L7LH56

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA159	96.528	100	0.965
comYF	Streptococcus mutans UA140	95.833	100	0.958
comGF	Lactococcus lactis subsp. cremoris KW2	43.262	97.917	0.424
comGF/cglF	Streptococcus pneumoniae Rx1	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae D39	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae R6	41.045	93.056	0.382
comGF/cglF	Streptococcus pneumoniae TIGR4	41.045	93.056	0.382
comGF/cglF	Streptococcus mitis NCTC 12261	39.552	93.056	0.368
comGF/cglF	Streptococcus mitis SK321	38.806	93.056	0.361