Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYE   Type   Machinery gene
Locus tag   SRT_RS01095 Genome accession   NZ_AP014612
Coordinates   213802..214095 (+) Length   97 a.a.
NCBI ID   WP_128832752.1    Uniprot ID   A0A1L7LH53
Organism   Streptococcus troglodytae strain TKU 31     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 208802..219095
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SRT_RS01070 (SRT_01910) - 210708..211091 (+) 384 WP_128832748.1 DUF1033 family protein -
  SRT_RS01075 comGA 211219..212158 (+) 940 Protein_179 competence type IV pilus ATPase ComGA -
  SRT_RS01080 (SRT_01940) comYB 212094..213125 (+) 1032 WP_256376016.1 competence type IV pilus assembly protein ComGB Machinery gene
  SRT_RS01085 (SRT_01950) comYC 213125..213439 (+) 315 WP_128832750.1 competence type IV pilus major pilin ComGC Machinery gene
  SRT_RS01090 (SRT_01960) comYD 213426..213830 (+) 405 WP_161940061.1 competence type IV pilus minor pilin ComGD Machinery gene
  SRT_RS01095 (SRT_01970) comYE 213802..214095 (+) 294 WP_128832752.1 competence type IV pilus minor pilin ComGE Machinery gene
  SRT_RS01100 (SRT_01980) comYF 214082..214516 (+) 435 WP_128832753.1 competence type IV pilus minor pilin ComGF Machinery gene
  SRT_RS01105 (SRT_01990) comYG 214494..214883 (+) 390 WP_128832754.1 competence type IV pilus minor pilin ComGG Machinery gene
  SRT_RS01110 (SRT_02010) - 214938..215890 (+) 953 Protein_186 class I SAM-dependent methyltransferase -
  SRT_RS01115 (SRT_02020) - 215949..217148 (+) 1200 WP_128832755.1 acetate kinase -
  SRT_RS01120 (SRT_02040) - 217692..217892 (+) 201 WP_128834002.1 helix-turn-helix transcriptional regulator -
  SRT_RS01125 (SRT_02050) - 217906..218345 (+) 440 Protein_189 hypothetical protein -
  SRT_RS01130 (SRT_02060) - 218397..219059 (+) 663 WP_128832757.1 type II CAAX endopeptidase family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10959.88 Da        Isoelectric Point: 9.5980

>NTDB_id=66155 SRT_RS01095 WP_128832752.1 213802..214095(+) (comYE) [Streptococcus troglodytae strain TKU 31]
MVSIKKQKVKAYILLESLVALGLFVAITTLILTQLSHHQERTAKNIQKQEILNLAIMALQTQQDHLSFNGVSVTVIKNQG
ETIVYHDHEEVINLVKK

Nucleotide


Download         Length: 294 bp        

>NTDB_id=66155 SRT_RS01095 WP_128832752.1 213802..214095(+) (comYE) [Streptococcus troglodytae strain TKU 31]
GTGGTCAGTATAAAAAAACAGAAAGTTAAAGCTTATATTCTTCTAGAAAGTTTAGTTGCTTTGGGGCTTTTCGTAGCCAT
CACAACTTTAATTCTTACTCAGTTGAGTCATCATCAGGAAAGGACAGCTAAAAATATACAAAAACAGGAAATATTGAATT
TAGCAATAATGGCTCTTCAAACTCAGCAAGATCATTTAAGTTTCAATGGCGTCAGTGTTACAGTTATTAAAAATCAAGGA
GAAACTATAGTTTATCATGATCATGAGGAGGTTATCAATCTTGTTAAAAAGTAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1L7LH53

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYE Streptococcus mutans UA140

95.876

100

0.959
  comYE Streptococcus mutans UA159

95.876

100

0.959
  comGE/cglE Streptococcus pneumoniae Rx1

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae D39

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae R6

43.333

92.784

0.402
  comGE/cglE Streptococcus pneumoniae TIGR4

43.333

92.784

0.402
  comGE/cglE Streptococcus mitis NCTC 12261

43.333

92.784

0.402
  comGE/cglE Streptococcus mitis SK321

43.333

92.784

0.402

Multiple sequence alignment