Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   ANG_RS05055 Genome accession   NZ_AP013072
Coordinates   996102..996806 (+) Length   234 a.a.
NCBI ID   WP_003034448.1    Uniprot ID   I0SIU4
Organism   Streptococcus anginosus subsp. whileyi MAS624     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 991102..1001806
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ANG_RS05035 (ANG_1012) - 991463..992668 (+) 1206 WP_003034551.1 multidrug efflux MFS transporter -
  ANG_RS10915 rpmG 992652..992801 (+) 150 WP_003034401.1 50S ribosomal protein L33 -
  ANG_RS05040 (ANG_1013) secG 992841..993074 (+) 234 WP_003024744.1 preprotein translocase subunit SecG -
  ANG_RS05045 (ANG_1014) rnr 993165..995504 (+) 2340 WP_003034491.1 ribonuclease R -
  ANG_RS05050 (ANG_1015) smpB 995467..995934 (+) 468 WP_003034458.1 SsrA-binding protein SmpB -
  ANG_RS05055 (ANG_1016) comEA/celA/cilE 996102..996806 (+) 705 WP_003034448.1 helix-hairpin-helix domain-containing protein Machinery gene
  ANG_RS05060 (ANG_1017) comEC/celB 996790..999018 (+) 2229 WP_025271751.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  ANG_RS05065 (ANG_1018) - 999099..999791 (+) 693 WP_020999586.1 DUF805 domain-containing protein -
  ANG_RS05070 (ANG_1020) - 1000296..1001282 (+) 987 WP_003034384.1 Gfo/Idh/MocA family protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 25344.70 Da        Isoelectric Point: 9.4255

>NTDB_id=65517 ANG_RS05055 WP_003034448.1 996102..996806(+) (comEA/celA/cilE) [Streptococcus anginosus subsp. whileyi MAS624]
MLEVIIKKIKEYKILVGLSLIGLIIAGFFLMTSKSARQSNVGDIAQEATNAKLERKETSTETKKKQQKEETESQKNLASE
ELEFLTVDVKGAVKNPGIYQLKKTSRINDAIQKAGGLTTDADSKSINLAQKLTDEAVIYVAAMGENVTNAASNNGQTLTT
DTNGTAAQKGNKVNLNKANLSDLQSISGIGQKRAQDILDYRESNGKFNSVDDLKNVSGVGAKTLEKLKEYVTVD

Nucleotide


Download         Length: 705 bp        

>NTDB_id=65517 ANG_RS05055 WP_003034448.1 996102..996806(+) (comEA/celA/cilE) [Streptococcus anginosus subsp. whileyi MAS624]
ATGTTAGAGGTAATCATCAAAAAAATAAAAGAGTATAAAATTTTAGTTGGTTTAAGCCTGATTGGTTTGATCATAGCAGG
ATTTTTTCTGATGACTAGTAAATCTGCTAGACAATCTAATGTAGGAGATATTGCACAAGAGGCCACAAATGCAAAACTAG
AACGGAAAGAAACTTCAACTGAAACGAAGAAAAAACAACAGAAAGAAGAAACAGAATCTCAAAAGAATTTAGCGAGTGAA
GAATTGGAATTTTTAACTGTAGATGTTAAAGGTGCTGTTAAAAATCCAGGTATTTATCAATTAAAAAAAACAAGCCGAAT
CAATGATGCTATCCAAAAAGCGGGTGGACTAACGACAGACGCTGACAGCAAATCTATCAATTTGGCTCAAAAACTAACAG
ATGAGGCTGTGATTTATGTGGCAGCTATGGGTGAAAATGTAACAAATGCTGCAAGTAATAATGGACAAACTTTAACGACA
GATACCAATGGAACTGCGGCACAAAAAGGGAATAAGGTCAATCTAAATAAGGCCAATTTGTCTGATTTACAGTCTATTTC
TGGTATTGGACAAAAGCGCGCCCAAGATATTTTAGATTATCGTGAGTCAAACGGGAAATTTAATTCTGTTGATGACTTGA
AAAATGTATCAGGAGTAGGCGCCAAAACACTAGAAAAATTGAAAGAATATGTCACAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(87-140)

Helix-hairpin-helix motif (HHH_3)

(169-232)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I0SIU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.073

99.573

0.509
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus mitis SK321

50.644

99.573

0.504
  comEA/celA/cilE Streptococcus pneumoniae Rx1

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae D39

50.215

99.573

0.5
  comEA/celA/cilE Streptococcus pneumoniae R6

50.215

99.573

0.5
  comEA Streptococcus thermophilus LMD-9

42.553

100

0.427
  comEA Lactococcus lactis subsp. cremoris KW2

37.768

99.573

0.376

Multiple sequence alignment