Detailed information NTG0065518

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: ANG_RS05060
• Genome accession: NZ_AP013072
• Coordinates: 996790..999018 (+)
• Length: 742 a.a.
• NCBI ID: WP_025271751.1
• Uniprot ID: -
• Organism: Streptococcus anginosus subsp. whileyi MAS624
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 991790..1004018

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ANG_RS10915	rpmG	992652..992801 (+)	150	WP_003034401.1	50S ribosomal protein L33	-
ANG_RS05040 (ANG_1013)	secG	992841..993074 (+)	234	WP_003024744.1	preprotein translocase subunit SecG	-
ANG_RS05045 (ANG_1014)	rnr	993165..995504 (+)	2340	WP_003034491.1	ribonuclease R	-
ANG_RS05050 (ANG_1015)	smpB	995467..995934 (+)	468	WP_003034458.1	SsrA-binding protein SmpB	-
ANG_RS05055 (ANG_1016)	comEA/celA/cilE	996102..996806 (+)	705	WP_003034448.1	helix-hairpin-helix domain-containing protein	Machinery gene
ANG_RS05060 (ANG_1017)	comEC/celB	996790..999018 (+)	2229	WP_025271751.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
ANG_RS05065 (ANG_1018)	-	999099..999791 (+)	693	WP_020999586.1	DUF805 domain-containing protein	-
ANG_RS05070 (ANG_1020)	-	1000296..1001282 (+)	987	WP_003034384.1	Gfo/Idh/MocA family protein	-
ANG_RS05075 (ANG_1021)	-	1001304..1001957 (+)	654	WP_003034489.1	uracil-DNA glycosylase	-
ANG_RS05080 (ANG_1022)	-	1001994..1002464 (+)	471	WP_003031692.1	NUDIX hydrolase	-
ANG_RS05085 (ANG_1023)	-	1002477..1003754 (+)	1278	WP_003034545.1	dihydroorotase	-

Sequence

Protein

• Length: 742 a.a.
• Molecular weight: 85115.00 Da
• Isoelectric Point: 9.9901

>NTDB_id=65518 ANG_RS05060 WP_025271751.1 996790..999018(+) (comEC/celB) [Streptococcus anginosus subsp. whileyi MAS624]
MSQWIKKFPIKPIYIAFLLVWLYFAIYQSSWLGWLGFIFLVIRLFRFYSPKECFMTFMILSCFVGFFFIRREMAERQANA
EPSPVKQIAVLPDTIKVNGDSLSFRGKTNGQTYQVYYKLKSKEEQLAFQNLSSLVILTVEGEFEIPEKKRNFAGFDYQSY
LKTQGIYRILKVDTILSSQYRISLHPFEWLSSWRRKALVFIKKHFPNPMSNYMTGLLFGALDTDFDEMNNLYSGLGIIHL
FALSGMQVGFFMEGFRKLLLRLGLTQEMVHKCQYPFSFFYAGMTGFSVSVVRSLVQKLLSQHGITKLDNFALTMMILSLI
MPSFLLTAGGVLSCAYAFVISVIDFESLTSWRKIVVESSVISLGVLPILIFYFGEFQPWSILLTFVFSLIFDTMMLPGLT
LIFLSSPLIKLTQVNFLFEGLENSIRWIASVFGRPIVFGQPSPLLLIVMLLVLAILYDIRKNKKWVIFLSLLLSLLFFIN
KFPLQNEITMVDVGQGDSIFLRDWKGRNVLIDVGGREEIRTKEAWQKRATSSNAEKTLIPYLKSRGIDTIDALVLTNPNP
DYAGDVLEVAKKFAIKKIYISRSSLSNADFLEKLRKINTFIHVVKQGDKLPIFDYHLQVLSGASKNDHSIVLYGQFFRTR
FLFASDLKEEGEAKLMQHYPKLKTDVLKVGQHGAKDSSSSKFLQQIEPTVALISVGKNNQSKQPSQDIIERFAQLPAKVY
RTDEQGAVKFSGWTNWRLEMVK

Nucleotide

• Length: 2229 bp

>NTDB_id=65518 ANG_RS05060 WP_025271751.1 996790..999018(+) (comEC/celB) [Streptococcus anginosus subsp. whileyi MAS624]
ATGTCACAGTGGATTAAAAAATTTCCGATTAAGCCGATTTACATTGCTTTCTTACTCGTCTGGTTATATTTTGCAATCTA
TCAAAGTAGCTGGTTAGGCTGGTTGGGTTTTATCTTTCTGGTGATTCGTCTTTTTCGCTTTTATTCACCAAAAGAATGTT
TCATGACCTTCATGATTCTCTCTTGTTTTGTTGGTTTTTTCTTTATTCGTAGGGAAATGGCAGAGCGGCAAGCAAATGCA
GAACCTTCTCCCGTAAAACAAATAGCAGTTCTACCTGACACGATTAAGGTAAATGGAGATTCACTTTCTTTCCGTGGTAA
AACAAATGGGCAGACTTATCAAGTTTACTACAAATTGAAATCAAAGGAAGAACAGTTGGCTTTTCAAAATCTCTCTAGTC
TGGTTATATTGACCGTTGAAGGGGAATTTGAAATCCCTGAGAAGAAGCGTAATTTTGCTGGTTTTGATTACCAATCCTAT
TTAAAAACGCAAGGGATTTATCGAATTTTAAAAGTGGATACCATTTTATCGAGCCAATACAGAATCAGCTTGCACCCTTT
TGAGTGGCTTTCTAGCTGGCGAAGAAAAGCACTGGTATTTATCAAGAAGCATTTTCCAAATCCGATGAGTAATTACATGA
CAGGACTCTTATTTGGTGCCTTGGATACAGACTTCGATGAAATGAACAATCTTTACTCTGGCTTGGGGATTATTCATTTA
TTTGCGCTGTCTGGCATGCAAGTTGGCTTTTTTATGGAGGGTTTTCGTAAGTTGCTGTTAAGGTTGGGTCTTACACAGGA
AATGGTCCATAAATGCCAATATCCATTTTCTTTCTTCTATGCGGGAATGACTGGATTTTCAGTATCCGTTGTACGAAGCT
TAGTTCAGAAATTATTGTCGCAACATGGTATCACTAAGTTAGATAATTTTGCTTTAACGATGATGATATTGTCCTTGATT
ATGCCTTCCTTTCTTTTAACGGCAGGAGGAGTTCTCTCTTGCGCCTATGCTTTTGTTATTAGTGTGATAGATTTTGAAAG
TCTGACTTCTTGGCGAAAGATTGTTGTAGAGAGCAGTGTCATTTCGCTTGGTGTTTTACCGATTCTAATCTTTTATTTTG
GTGAATTTCAACCTTGGTCTATTTTGTTGACATTTGTTTTTTCACTAATTTTCGATACAATGATGCTGCCAGGCTTGACG
TTGATTTTTCTTTCTTCGCCTTTGATAAAGCTAACTCAGGTCAATTTTCTATTTGAAGGGTTAGAAAATAGCATTCGTTG
GATAGCAAGTGTCTTTGGCAGACCAATCGTTTTTGGGCAACCCAGTCCGCTTTTGCTGATTGTTATGCTACTTGTACTGG
CTATTTTGTATGATATTAGAAAAAATAAAAAATGGGTAATATTTCTTAGTCTGCTTCTTTCATTACTCTTTTTCATAAAT
AAATTTCCCTTGCAAAATGAGATCACAATGGTTGATGTTGGGCAGGGAGATAGTATTTTTCTGAGAGACTGGAAAGGACG
AAATGTATTGATTGATGTTGGGGGACGTGAGGAAATTAGAACAAAAGAAGCTTGGCAAAAACGAGCGACTAGCTCAAATG
CAGAGAAAACTTTGATTCCTTACTTAAAAAGTCGTGGCATAGATACGATTGATGCTTTAGTCTTAACAAATCCTAATCCA
GATTATGCAGGAGATGTATTAGAAGTTGCTAAAAAATTTGCAATAAAGAAAATTTATATTTCCAGAAGTAGTCTAAGCAA
TGCAGATTTTCTAGAGAAATTAAGGAAAATAAACACATTCATTCATGTTGTAAAACAAGGCGACAAACTTCCTATTTTTG
ATTATCATTTGCAAGTTCTTTCGGGTGCTAGCAAGAACGACCATTCGATCGTTTTATATGGTCAGTTTTTCCGTACAAGA
TTTTTATTTGCGAGCGACTTGAAAGAAGAGGGCGAAGCAAAGTTAATGCAGCATTATCCAAAGTTGAAAACAGATGTTTT
GAAAGTCGGACAGCATGGAGCCAAGGACTCATCAAGTTCAAAATTTTTACAACAAATAGAACCAACGGTCGCTCTCATTT
CTGTTGGGAAAAATAATCAATCTAAGCAACCAAGTCAAGATATAATAGAGCGATTTGCACAATTGCCTGCTAAGGTCTAT
CGGACAGATGAACAAGGGGCAGTTAAATTTTCAGGGTGGACAAACTGGCGATTAGAGATGGTCAAGTAA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-592)

• Domain of unknown function (DUF4131) (DUF4131) (30-175)

• Competence protein (Competence) (216-460)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis SK321	55.615	100	0.561
comEC/celB	Streptococcus mitis NCTC 12261	54.886	100	0.553
comEC/celB	Streptococcus pneumoniae TIGR4	54.545	100	0.55
comEC/celB	Streptococcus pneumoniae Rx1	53.61	100	0.54
comEC/celB	Streptococcus pneumoniae D39	53.61	100	0.54
comEC/celB	Streptococcus pneumoniae R6	53.61	100	0.54
comEC	Lactococcus lactis subsp. cremoris KW2	47.383	100	0.476