Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SPB_RS10315 Genome accession   NZ_AEUT02000001
Coordinates   2041403..2042674 (+) Length   423 a.a.
NCBI ID   WP_003103228.1    Uniprot ID   A0A0E2UCS4
Organism   Streptococcus parauberis NCFD 2020     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2036403..2047674
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPB_RS10295 (SPB_2124) mutL 2036654..2038630 (+) 1977 WP_003102604.1 DNA mismatch repair endonuclease MutL -
  SPB_RS10300 (SPB_2125) - 2038641..2039864 (+) 1224 WP_003103803.1 MFS transporter -
  SPB_RS10305 (SPB_2126) ruvA 2039866..2040459 (+) 594 WP_003103584.1 Holliday junction branch migration protein RuvA -
  SPB_RS10310 (SPB_2127) - 2040463..2041014 (+) 552 WP_003104649.1 DNA-3-methyladenine glycosylase I -
  SPB_RS10315 (SPB_2128) cinA 2041403..2042674 (+) 1272 WP_003103228.1 competence/damage-inducible protein A Machinery gene
  SPB_RS10320 (SPB_2129) recA 2042754..2043893 (+) 1140 WP_003102546.1 recombinase RecA Machinery gene
  SPB_RS10325 (SPB_2130) spx 2044248..2044646 (+) 399 WP_003104943.1 transcriptional regulator Spx -
  SPB_RS10330 (SPB_2131) - 2044760..2045029 (+) 270 WP_003104158.1 IreB family regulatory phosphoprotein -
  SPB_RS10335 (SPB_2132) ruvX 2045026..2045445 (+) 420 WP_003105581.1 Holliday junction resolvase RuvX -
  SPB_RS10340 (SPB_2133) - 2045456..2045773 (+) 318 WP_003104776.1 DUF1292 domain-containing protein -
  SPB_RS10345 (SPB_2134) - 2045922..2047481 (+) 1560 WP_003103459.1 membrane protein -

Sequence

Protein


Download         Length: 423 a.a.        Molecular weight: 46101.75 Da        Isoelectric Point: 4.8894

>NTDB_id=64574 SPB_RS10315 WP_003103228.1 2041403..2042674(+) (cinA) [Streptococcus parauberis NCFD 2020]
MKAELIAVGTEILTGQIVNTNAQFLSEKMAEIGVDVYYHTAVGDNEIRLLNILEVASKRSDLVILCGGLGPTEDDLTKQT
LAKFLGLSLVFDREASQKLDQFFSSRSESSRTPNNERQAQLIEGSKPIQNITGLAVGGLIEKAGVTYVVLPGPPSELKPM
VNQYLLPLLLNEETKLYSRVLRFFGIGESQLVTILADLIANQSDPTIAPYAKIGEVTLRLSTKSDSQELAYQKLDQLESQ
IKAISTIDGQLLGDLLYGYGEDNSLARETFQLLKKADKTITAAESLTAGLFQSKIADFPGSSSIFNGGFVTYSIEEKAKM
LEIPFADLQRKGVVSDYTAKQMANQARLLTESDIGVSLTGVAGPDFLEGQQAGTVFIGISTKEKVESYKVLIGGRSRSDV
RYIACLHAFNLVRKTLLNTQNLL

Nucleotide


Download         Length: 1272 bp        

>NTDB_id=64574 SPB_RS10315 WP_003103228.1 2041403..2042674(+) (cinA) [Streptococcus parauberis NCFD 2020]
ATGAAAGCTGAATTAATTGCAGTCGGAACAGAAATCTTGACCGGTCAAATAGTTAATACGAACGCACAGTTTTTATCAGA
AAAAATGGCAGAGATTGGAGTTGATGTCTATTATCATACAGCAGTAGGCGATAATGAAATCAGATTATTAAATATCCTTG
AAGTTGCAAGTAAACGTAGTGATTTAGTGATATTATGTGGCGGTTTGGGACCTACTGAGGATGATTTGACTAAACAAACG
CTAGCTAAGTTTTTAGGTCTGTCATTGGTCTTTGACAGAGAAGCTAGTCAAAAACTGGACCAATTTTTTTCCTCTCGGTC
TGAGAGTTCTAGAACTCCAAATAATGAGAGGCAAGCACAGTTGATTGAAGGGTCCAAACCTATTCAAAATATTACAGGTC
TAGCTGTTGGTGGTTTAATCGAAAAAGCTGGTGTAACTTATGTCGTCTTACCTGGACCGCCTAGTGAATTGAAACCAATG
GTTAATCAGTATCTACTACCACTGTTGCTGAATGAGGAAACTAAACTCTACTCTCGTGTTTTACGTTTTTTTGGAATTGG
AGAAAGCCAATTAGTTACTATTTTAGCTGATCTTATTGCAAATCAATCAGACCCAACAATTGCTCCCTATGCCAAAATCG
GCGAGGTAACATTGCGCTTGTCAACTAAGTCTGATTCTCAAGAGCTAGCTTATCAAAAATTGGATCAATTAGAAAGTCAG
ATTAAGGCCATTTCAACTATAGATGGACAATTATTAGGAGACTTATTATATGGATATGGTGAGGATAATAGCCTGGCGCG
TGAGACTTTCCAGTTGTTAAAAAAAGCAGATAAGACAATTACAGCTGCAGAAAGTTTAACAGCAGGGCTATTCCAATCTA
AAATTGCTGATTTTCCAGGGTCATCCAGTATTTTTAACGGTGGATTTGTTACCTATAGTATCGAAGAAAAGGCAAAAATG
TTAGAGATTCCATTTGCTGATTTACAACGAAAAGGTGTTGTTAGTGATTATACTGCTAAACAAATGGCTAATCAAGCACG
ACTCTTAACTGAAAGTGATATTGGTGTTAGCTTAACTGGCGTTGCTGGTCCGGATTTCTTGGAAGGACAACAAGCAGGAA
CAGTTTTTATTGGTATTTCGACAAAAGAAAAAGTAGAATCATATAAGGTACTAATTGGCGGCAGGAGTCGCTCAGATGTC
AGATATATAGCTTGCTTACATGCCTTCAACCTAGTCCGAAAAACTTTATTAAATACCCAAAATTTGTTATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Competence-damaged protein (CinA)

(263-416)

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E2UCS4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

71.292

98.818

0.704
  cinA Streptococcus mitis NCTC 12261

71.053

98.818

0.702
  cinA Streptococcus mutans UA159

70.213

100

0.702
  cinA Streptococcus pneumoniae TIGR4

70.096

98.818

0.693
  cinA Streptococcus pneumoniae Rx1

69.856

98.818

0.69
  cinA Streptococcus pneumoniae R6

69.856

98.818

0.69
  cinA Streptococcus pneumoniae D39

69.617

98.818

0.688
  cinA Streptococcus suis isolate S10

53.606

98.345

0.527
  cinA Bacillus subtilis subsp. subtilis str. 168

46.651

98.818

0.461

Multiple sequence alignment