Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   N596_RS00845 Genome accession   NC_022584
Coordinates   144143..144820 (+) Length   225 a.a.
NCBI ID   WP_023026596.1    Uniprot ID   A0A3A5QCQ0
Organism   Streptococcus ilei     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 139143..149820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS00825 (N596_00855) - 139699..139986 (-) 288 WP_042361012.1 GIY-YIG nuclease family protein -
  N596_RS00830 (N596_00860) - 139976..140722 (-) 747 WP_023026593.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  N596_RS00835 (N596_00865) - 140821..143160 (-) 2340 WP_023026594.1 HAD-IC family P-type ATPase -
  N596_RS00840 (N596_00870) - 143298..144041 (+) 744 WP_023026595.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  N596_RS00845 (N596_00875) comEA/celA/cilE 144143..144820 (+) 678 WP_023026596.1 helix-hairpin-helix domain-containing protein Machinery gene
  N596_RS00850 (N596_00880) comEC/celB 144804..147044 (+) 2241 WP_023026597.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  N596_RS00855 (N596_00885) - 147107..147772 (+) 666 WP_023026598.1 DUF805 domain-containing protein -
  N596_RS00860 (N596_00890) holA 147750..148787 (+) 1038 WP_023022678.1 DNA polymerase III subunit delta -
  N596_RS00865 (N596_00895) sodA 148859..149464 (+) 606 WP_023022680.1 superoxide dismutase SodA -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24395.36 Da        Isoelectric Point: 4.5812

>NTDB_id=62939 N596_RS00845 WP_023026596.1 144143..144820(+) (comEA/celA/cilE) [Streptococcus ilei]
METWIEKIKEYKLFLGLVAVGLVVGGVFLFWPKPTPQAPETVISQLEMVEQESSPKGDSSFTSSSQERSEEKTDSSHEKI
MVDVKGAVRQAGVYELPVGSRVYDAVQKAGGMTDEANSQSVNLAQKLEDESIVYVAKNGEEVAPVASASAGTTGGENQQK
DGKVNLNTATEAELQTISGIGQKRAQDIIAYREEKGKFQSVDELKNVSGIGQKMLEKLKEHVTVD

Nucleotide


Download         Length: 678 bp        

>NTDB_id=62939 N596_RS00845 WP_023026596.1 144143..144820(+) (comEA/celA/cilE) [Streptococcus ilei]
ATGGAGACATGGATTGAGAAGATCAAGGAATATAAACTGTTTTTAGGCTTGGTTGCTGTGGGGCTAGTGGTGGGAGGAGT
GTTTCTCTTTTGGCCTAAGCCAACCCCACAAGCACCGGAAACGGTCATTTCTCAGTTAGAAATGGTGGAGCAAGAGAGTT
CTCCTAAGGGAGATTCAAGCTTTACTTCGAGCTCTCAGGAGAGAAGTGAGGAAAAGACCGACTCCTCGCATGAGAAAATC
ATGGTGGATGTGAAGGGGGCTGTCAGACAAGCGGGAGTCTATGAGCTTCCGGTGGGGAGTCGGGTCTATGATGCAGTGCA
AAAAGCAGGAGGGATGACAGACGAAGCCAATAGCCAATCTGTCAACTTGGCTCAAAAATTAGAGGATGAGTCTATTGTCT
ATGTTGCTAAGAATGGAGAAGAAGTGGCGCCTGTAGCGTCTGCTTCTGCTGGGACCACAGGTGGTGAAAACCAGCAAAAG
GATGGCAAGGTTAATCTCAATACAGCCACAGAAGCAGAATTACAGACTATTTCTGGGATTGGTCAAAAACGAGCTCAGGA
TATCATTGCTTATCGAGAGGAAAAAGGAAAATTTCAATCTGTTGATGAATTGAAAAATGTTTCTGGGATTGGCCAAAAGA
TGTTAGAAAAGTTAAAAGAGCATGTTACAGTGGATTAG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(81-133)

Helix-hairpin-helix motif (HHH_3)

(161-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3A5QCQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

51.982

100

0.524
  comEA/celA/cilE Streptococcus pneumoniae R6

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae Rx1

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae D39

49.78

100

0.502
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

50.222

100

0.502
  comEA/celA/cilE Streptococcus mitis SK321

49.558

100

0.498
  comEA Streptococcus thermophilus LMD-9

44.298

100

0.449
  comEA Lactococcus lactis subsp. cremoris KW2

39.474

100

0.4

Multiple sequence alignment