Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   N596_RS00850 Genome accession   NC_022584
Coordinates   144804..147044 (+) Length   746 a.a.
NCBI ID   WP_023026597.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 139804..152044
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N596_RS00830 (N596_00860) - 139976..140722 (-) 747 WP_023026593.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  N596_RS00835 (N596_00865) - 140821..143160 (-) 2340 WP_023026594.1 HAD-IC family P-type ATPase -
  N596_RS00840 (N596_00870) - 143298..144041 (+) 744 WP_023026595.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  N596_RS00845 (N596_00875) comEA/celA/cilE 144143..144820 (+) 678 WP_023026596.1 helix-hairpin-helix domain-containing protein Machinery gene
  N596_RS00850 (N596_00880) comEC/celB 144804..147044 (+) 2241 WP_023026597.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  N596_RS00855 (N596_00885) - 147107..147772 (+) 666 WP_023026598.1 DUF805 domain-containing protein -
  N596_RS00860 (N596_00890) holA 147750..148787 (+) 1038 WP_023022678.1 DNA polymerase III subunit delta -
  N596_RS00865 (N596_00895) sodA 148859..149464 (+) 606 WP_023022680.1 superoxide dismutase SodA -
  N596_RS00870 (N596_00900) - 149719..151191 (+) 1473 WP_023022682.1 helicase HerA-like domain-containing protein -

Sequence

Protein


Download         Length: 746 a.a.        Molecular weight: 85873.55 Da        Isoelectric Point: 9.6033

>NTDB_id=62940 N596_RS00850 WP_023026597.1 144804..147044(+) (comEC/celB) [Streptococcus ilei]
MLQWIRSINIHPFHLTLPVLALYYWMYTGHLLAPIFLLAFFILFSRRYNGKQFLILIGLLLFATLCFAFRIEHGKQEARD
QEVPRVIQLLPDTIKVNGDALSFRAQSGSRTFQVFYQLQTKEEQAYFKHLDHGLELRIKGELETPTKQRNFMGFDYQAYL
KTQGIYHLLKISQILEKRPAEPRDLIGLLSSWRRKALVWVHQHFPQPMSHYMTGLLFGFLDVEFEEMSQLYSNLGIIHLF
ALSGMQVAFFLDTFRRFFLRLGLEQEKVATLLYPFSLLYAGMTGFSVSVVRSLIQKLLAQQGLKGMENMGMTLLLLLLFL
PSSLLTAGGLLSCAYAFILTLTSSEEEKSGIRKVVKESLVLTLGVLPFLIFFFGEYQPWSLPLTFVFSLLFDVLLLPGLS
VVFLLSFLYPLTFWNPFFIWMEKSMESIAGFTSQSLVFGQPSISFFLLLLFLLAFLYEMRKVKKWRYLFLLLVCSVFAIV
KHPLENEITIIDIGQGDSILLRDWRGKTILIDTGGKVDFGQKEAWRNRRSTSNAERTLLPYLKSRGIDQIDHMVLTHTDT
DHMGDLEVLAAKVSIKEINISKGSLKKDSFVRLLKRLNLPVKTLEAGDQLSIFDGSAEVLYPVEVGDGSNNDSLVLYGRF
YGWTFLFTGDLEEEGEKTLLARYPQLRVDVLKAGHHGSKGSSHPAFLRRIQAKIALISAGEKNRYQHPHQETLERFKELQ
MMVFRTDQQGAIRFRGWNQWKIETVR

Nucleotide


Download         Length: 2241 bp        

>NTDB_id=62940 N596_RS00850 WP_023026597.1 144804..147044(+) (comEC/celB) [Streptococcus ilei]
ATGTTACAGTGGATTAGAAGCATCAATATTCATCCATTTCATCTGACTCTTCCCGTCTTGGCTCTTTATTATTGGATGTA
TACAGGTCACTTGCTCGCTCCAATCTTCCTTCTGGCCTTCTTCATCTTGTTTAGTAGACGCTACAATGGCAAACAATTTC
TAATCCTAATAGGGCTTCTCTTGTTTGCTACACTTTGTTTTGCTTTTCGAATCGAACATGGTAAGCAGGAAGCGCGGGAT
CAAGAGGTTCCAAGGGTTATTCAGCTCTTACCAGATACCATCAAGGTGAATGGAGATGCCTTATCCTTTCGTGCTCAGTC
AGGTAGTCGTACTTTTCAGGTTTTCTATCAGCTTCAGACAAAAGAAGAACAAGCCTATTTTAAACACTTGGATCATGGGC
TAGAATTAAGAATAAAAGGAGAATTAGAGACCCCGACAAAACAGCGAAATTTCATGGGCTTTGATTACCAGGCTTATCTG
AAAACACAAGGGATCTATCATCTTTTGAAAATCAGCCAGATCCTTGAAAAGAGACCTGCTGAACCTAGAGATTTAATAGG
CCTCCTGTCTAGTTGGAGGCGGAAGGCTCTTGTGTGGGTTCACCAGCATTTCCCCCAGCCCATGAGTCACTATATGACGG
GCTTGCTTTTTGGTTTTTTAGATGTAGAGTTCGAAGAAATGAGTCAGCTGTATTCGAACTTGGGGATTATCCATCTGTTC
GCCTTGTCGGGCATGCAGGTCGCTTTCTTCTTAGATACTTTTCGACGATTCTTTCTTCGCTTGGGATTGGAGCAGGAAAA
AGTTGCAACCCTCCTCTATCCGTTTTCGCTTCTTTATGCTGGGATGACGGGCTTTTCGGTTTCGGTCGTTCGAAGCCTTA
TACAGAAGCTCCTAGCCCAGCAAGGTCTCAAAGGAATGGAGAATATGGGGATGACCCTCCTCTTGTTGCTCCTTTTTCTG
CCTTCTTCATTATTGACTGCTGGAGGACTCTTATCTTGTGCCTACGCTTTTATATTGACGCTAACCTCTTCCGAGGAGGA
GAAGTCAGGAATACGAAAAGTCGTCAAGGAGAGTCTGGTGTTAACACTAGGGGTTCTTCCTTTTTTGATTTTTTTCTTTG
GAGAATACCAGCCCTGGTCTCTTCCTCTAACCTTTGTTTTTTCCCTCTTATTTGATGTCCTTTTGTTACCAGGACTGAGT
GTCGTCTTTCTCCTCTCATTTCTATATCCATTGACCTTCTGGAATCCCTTCTTCATCTGGATGGAAAAAAGTATGGAGTC
TATAGCGGGATTTACCAGTCAATCTTTGGTTTTTGGACAACCAAGTATTTCTTTCTTCCTCTTGCTGTTATTCTTATTGG
CTTTCCTCTATGAGATGCGAAAGGTTAAGAAGTGGAGATATCTTTTTCTACTCTTAGTCTGCTCCGTATTCGCCATTGTG
AAGCATCCTTTAGAAAATGAGATTACCATCATTGATATTGGCCAAGGTGATAGTATTTTGCTACGTGATTGGCGAGGGAA
GACGATCCTAATTGATACAGGTGGAAAAGTGGACTTTGGCCAAAAGGAAGCATGGAGGAATCGGAGGTCTACTAGCAATG
CAGAACGGACCTTGCTTCCTTATCTCAAAAGTAGAGGGATTGATCAGATTGACCATATGGTTCTCACGCATACTGACACA
GATCATATGGGAGATTTGGAAGTCCTTGCGGCTAAGGTTAGCATTAAGGAAATCAACATTTCCAAGGGAAGCTTAAAAAA
AGACTCCTTTGTCCGTTTGCTCAAACGGTTAAACCTACCTGTAAAGACGCTGGAGGCTGGTGATCAACTGTCAATCTTTG
ATGGGAGTGCAGAAGTTCTCTATCCGGTAGAAGTAGGAGATGGGAGTAATAACGATTCTCTTGTTCTCTATGGCCGGTTT
TATGGTTGGACCTTCCTTTTTACAGGAGATTTAGAAGAAGAGGGGGAAAAGACCTTGTTAGCCCGCTATCCTCAACTGCG
CGTGGATGTATTAAAAGCAGGGCACCATGGTTCTAAGGGCTCTTCTCACCCAGCCTTCTTAAGGCGAATCCAAGCAAAAA
TTGCCTTGATATCTGCGGGAGAAAAAAATCGTTACCAGCATCCTCATCAGGAAACCTTGGAGCGATTTAAAGAGTTGCAG
ATGATGGTTTTTCGGACAGATCAGCAAGGAGCGATTCGTTTTAGAGGATGGAATCAGTGGAAGATTGAAACCGTTCGATA
A

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(32-174)

Metallo-beta-lactamase superfamily (Lactamase_B)

(494-700)

Competence protein (Competence)

(215-459)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis NCTC 12261

52.4

100

0.527
  comEC/celB Streptococcus mitis SK321

51.995

100

0.524
  comEC/celB Streptococcus pneumoniae TIGR4

51.66

100

0.521
  comEC/celB Streptococcus pneumoniae Rx1

51.398

100

0.517
  comEC/celB Streptococcus pneumoniae D39

51.398

100

0.517
  comEC/celB Streptococcus pneumoniae R6

51.398

100

0.517
  comEC Lactococcus lactis subsp. cremoris KW2

44.429

98.66

0.438

Multiple sequence alignment