Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   N597_RS00240 Genome accession   NC_022582
Coordinates   47641..48663 (+) Length   340 a.a.
NCBI ID   WP_023022075.1    Uniprot ID   -
Organism   Streptococcus ilei     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 42641..53663
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  N597_RS00215 (N597_00220) - 42715..43503 (+) 789 WP_006595143.1 hypothetical protein -
  N597_RS10525 (N597_00225) - 43513..43653 (+) 141 WP_006595142.1 hypothetical protein -
  N597_RS00220 (N597_00230) - 43646..44956 (+) 1311 WP_023022074.1 glycosyltransferase family 2 protein -
  N597_RS00225 (N597_00235) - 44965..46068 (+) 1104 WP_006595140.1 glycosyl hydrolase family 8 -
  N597_RS00230 (N597_00240) - 46275..46652 (+) 378 WP_006595139.1 DUF1033 family protein -
  N597_RS00235 (N597_00245) comYA 46758..47699 (+) 942 WP_006597118.1 competence type IV pilus ATPase ComGA Machinery gene
  N597_RS00240 (N597_00250) comYB 47641..48663 (+) 1023 WP_023022075.1 competence type IV pilus assembly protein ComGB Machinery gene
  N597_RS00245 (N597_00255) comYC 48660..48977 (+) 318 WP_023022076.1 competence type IV pilus major pilin ComGC Machinery gene
  N597_RS00250 (N597_00260) comGD/cglD 48946..49371 (+) 426 WP_042507426.1 competence type IV pilus minor pilin ComGD Machinery gene
  N597_RS00255 (N597_00265) comGE 49337..49630 (+) 294 WP_006595134.1 competence type IV pilus minor pilin ComGE -
  N597_RS00260 (N597_00270) comGF/cglF 49614..50066 (+) 453 WP_040803180.1 competence type IV pilus minor pilin ComGF Machinery gene
  N597_RS00265 (N597_00275) comGG 50032..50478 (+) 447 WP_006595132.1 competence type IV pilus minor pilin ComGG -
  N597_RS00270 (N597_00280) comYH 50510..51463 (+) 954 WP_023022079.1 class I SAM-dependent methyltransferase Machinery gene
  N597_RS00275 (N597_00285) - 51512..52708 (+) 1197 WP_023022080.1 acetate kinase -
  N597_RS00280 (N597_00290) - 52860..53534 (+) 675 WP_224781595.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 340 a.a.        Molecular weight: 38969.06 Da        Isoelectric Point: 9.9519

>NTDB_id=62874 N597_RS00240 WP_023022075.1 47641..48663(+) (comYB) [Streptococcus ilei]
MKRDILSWIRRKPKKLSIAKQEHVIELFHNLYSSGFHLSEVIDFLRRSQLVEADFVERMQVGLANGKPLSAILSDLGFSD
QVTTQLALAEQHGNVTLSLEKIRSYLENLTQVRKKLVEVATYPVLLLGFLILIMLGLKNYLLPQLENQNGATRLISIFPQ
YVLLGSVLLTIGVLMLLFLGRRAKRLALVSCLARFPFLRPFLQDYLTAFYAREWGSMIAQGLELNQIFPVMQGQRSRLFR
EIGQDLERALARGRSFSDHIQTYPFFKRELALMIEYGEAKSKLGSELEIYADKTWAGFFHRLNKAMNVVQPLVFVFVALM
IVLLYAAMLLPIYENLEVPL

Nucleotide


Download         Length: 1023 bp        

>NTDB_id=62874 N597_RS00240 WP_023022075.1 47641..48663(+) (comYB) [Streptococcus ilei]
ATGAAGCGGGACATATTGAGCTGGATCAGGCGCAAGCCGAAAAAATTATCGATTGCTAAGCAAGAACATGTCATTGAACT
CTTTCACAATCTCTACAGCAGTGGCTTTCATCTATCAGAGGTCATCGACTTTCTTCGGCGCAGTCAATTGGTAGAGGCAG
ATTTTGTCGAGAGGATGCAGGTCGGACTTGCCAACGGGAAGCCCCTGTCAGCCATTCTCTCTGATCTAGGTTTCTCCGAT
CAGGTAACGACTCAATTGGCACTGGCGGAGCAGCATGGAAATGTTACCTTAAGTTTAGAAAAGATCCGTAGCTACTTGGA
AAATCTGACCCAGGTTCGAAAGAAACTAGTTGAGGTGGCGACCTATCCCGTGCTCTTGTTGGGATTTTTGATCTTGATTA
TGCTGGGGCTGAAAAATTATCTCTTGCCCCAGTTGGAGAATCAAAATGGGGCGACACGACTGATTAGTATCTTTCCCCAG
TATGTTTTGTTAGGGAGTGTGTTGCTGACGATTGGAGTTTTGATGCTCCTTTTCCTAGGCCGTCGTGCCAAACGGCTGGC
CCTGGTTTCATGTTTGGCTAGATTTCCTTTTCTTCGCCCCTTCTTACAGGATTATCTGACCGCTTTTTATGCTCGAGAAT
GGGGAAGTATGATTGCCCAAGGGTTGGAGCTGAATCAAATTTTTCCTGTGATGCAGGGGCAACGTTCCCGTCTCTTTCGA
GAGATTGGACAGGATTTAGAGCGGGCATTGGCTCGTGGCAGGTCTTTTTCTGACCATATTCAGACCTATCCTTTCTTTAA
ACGAGAGCTGGCCCTCATGATTGAATATGGGGAAGCCAAATCCAAGCTCGGTAGTGAGCTGGAGATCTATGCAGACAAGA
CCTGGGCAGGCTTTTTCCATCGTTTGAACAAGGCCATGAATGTCGTTCAACCACTGGTCTTTGTCTTTGTTGCTCTTATG
ATTGTTTTGCTCTATGCAGCCATGTTGCTGCCGATTTATGAAAATTTGGAGGTTCCTTTATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(26-143)

Type II secretion system (T2SS), protein F (T2SSF)

(211-331)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

61.404

100

0.618
  comGB/cglB Streptococcus mitis NCTC 12261

60.417

98.824

0.597
  comGB/cglB Streptococcus mitis SK321

59.821

98.824

0.591
  comGB/cglB Streptococcus pneumoniae Rx1

59.226

98.824

0.585
  comGB/cglB Streptococcus pneumoniae D39

59.226

98.824

0.585
  comGB/cglB Streptococcus pneumoniae R6

59.226

98.824

0.585
  comGB/cglB Streptococcus pneumoniae TIGR4

59.226

98.824

0.585
  comYB Streptococcus mutans UA159

58.991

93.235

0.55
  comYB Streptococcus mutans UA140

58.991

93.235

0.55
  comGB Lactococcus lactis subsp. cremoris KW2

48.98

100

0.494

Multiple sequence alignment