Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SIR_RS18955 Genome accession   NC_022246
Coordinates   1885388..1886656 (-) Length   422 a.a.
NCBI ID   WP_021003314.1    Uniprot ID   T1ZH31
Organism   Streptococcus intermedius B196     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1880388..1891656
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS18920 (SIR_1798) - 1881107..1881412 (-) 306 WP_003075274.1 DUF1292 domain-containing protein -
  SIR_RS18925 (SIR_1799) ruvX 1881430..1881849 (-) 420 WP_021003313.1 Holliday junction resolvase RuvX -
  SIR_RS18930 (SIR_1800) - 1881849..1882115 (-) 267 WP_009569646.1 IreB family regulatory phosphoprotein -
  SIR_RS18935 (SIR_1801) - 1882421..1882978 (-) 558 WP_020999236.1 SP0191 family lipoprotein -
  SIR_RS20355 - 1883168..1883332 (-) 165 WP_327083042.1 hypothetical protein -
  SIR_RS20250 - 1883401..1883628 (-) 228 WP_041787613.1 hypothetical protein -
  SIR_RS18945 (SIR_1802) spx 1883710..1884108 (-) 399 WP_003026638.1 transcriptional regulator Spx -
  SIR_RS18950 (SIR_1803) recA 1884194..1885339 (-) 1146 WP_003077215.1 recombinase RecA Machinery gene
  SIR_RS18955 (SIR_1804) cinA 1885388..1886656 (-) 1269 WP_021003314.1 competence/damage-inducible protein A Machinery gene
  SIR_RS18960 (SIR_1805) - 1886949..1890863 (-) 3915 WP_021003315.1 Cna B-type domain-containing protein -
  SIR_RS20255 - 1891255..1891576 (+) 322 Protein_1794 transposase -

Sequence

Protein


Download         Length: 422 a.a.        Molecular weight: 45566.11 Da        Isoelectric Point: 5.8217

>NTDB_id=61921 SIR_RS18955 WP_021003314.1 1885388..1886656(-) (cinA) [Streptococcus intermedius B196]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTAVGDNEDRLLSILEIARDRSNLVILTGGLGPTEDDLTKQT
LSKFLNRRLVFYQVAVEKLNRFFSSRPDYTRTLNNERQAQIVEGSTPLPNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLATGQKLYSRVLRFFGIGESQLVTLLGNLIDTQTDPTIAPYAKTGEVTLRLSTKASSQKEADVKFAHLEKKI
LAVQTFEKQQLADLFYAYGDDNSLGQTAFELLKKAGKTVTAAESLTAGLFQATLANFSGASKVFGGGFVTYGIEEKSQML
GIPLADLEMHGVVSAYTAEKMATQARKLTASDYAVSLTGVAGPDSLEGHPAGTVYIGLATADNVQSIQVNIAERSRTDVR
KIAVLHAFNLLRKTLLKNENML

Nucleotide


Download         Length: 1269 bp        

>NTDB_id=61921 SIR_RS18955 WP_021003314.1 1885388..1886656(-) (cinA) [Streptococcus intermedius B196]
ATGAAAGCAGAAATTATTGCTGTGGGTACTGAGATTTTGACTGGTCAGATTGTCAATACGAATGCTCAATTTTTATCTGA
AAAATTAGCGAGCTTGGGAGTAGATGTCTATTTCCAGACAGCGGTTGGAGATAATGAAGATCGTCTGTTATCCATTTTAG
AAATAGCTAGAGATCGTAGTAATTTAGTTATCTTGACAGGTGGTTTAGGTCCGACTGAAGACGACTTAACCAAGCAGACT
TTGTCAAAATTTTTGAATCGTAGGCTAGTCTTTTATCAAGTAGCTGTTGAAAAATTGAATCGTTTCTTCTCCAGCCGACC
GGACTATACTCGAACACTAAATAATGAGCGACAAGCTCAGATAGTAGAAGGCTCGACTCCTTTACCAAATGCGACCGGCT
TAGCTGTCGGAGGATTGTTAGAAGCAGACGGAGTGACCTATGTAGTCCTGCCTGGCCCCCCTAGTGAACTAAAGCCTATG
GTAAACAATGAGTTGGTTCCGCTTTTAGCAACTGGCCAAAAATTGTATTCGAGAGTCTTGCGTTTCTTTGGTATTGGGGA
GAGTCAATTAGTCACCCTTTTAGGAAACTTGATTGATACTCAGACGGATCCGACCATTGCTCCTTATGCTAAGACGGGAG
AAGTGACGTTGCGATTGTCGACCAAGGCCAGCAGTCAAAAGGAAGCAGATGTTAAGTTTGCTCATCTGGAAAAGAAAATT
TTAGCAGTACAGACTTTTGAGAAACAACAATTAGCCGACCTTTTCTATGCTTATGGAGATGATAATTCTCTGGGACAGAC
AGCTTTTGAATTGTTGAAGAAAGCAGGCAAAACAGTCACAGCAGCTGAAAGTCTGACTGCGGGACTTTTTCAAGCGACTT
TAGCAAATTTTTCTGGAGCATCCAAGGTCTTTGGAGGTGGCTTTGTTACTTATGGCATAGAGGAGAAGAGTCAAATGTTA
GGCATTCCATTGGCAGATTTAGAAATGCATGGGGTAGTCTCAGCTTATACAGCAGAGAAAATGGCTACGCAAGCTAGGAA
ATTGACTGCTAGTGACTATGCGGTGAGTTTGACTGGAGTAGCAGGTCCAGATAGTTTAGAAGGCCATCCAGCAGGAACTG
TTTATATTGGCTTGGCAACTGCAGATAACGTTCAGTCTATTCAGGTTAATATTGCGGAGCGCAGTCGGACGGATGTACGT
AAAATAGCTGTGTTACATGCTTTCAATTTGTTGCGAAAAACTTTATTAAAAAATGAGAATATGCTATAA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(263-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB T1ZH31

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

74.88

99.052

0.742
  cinA Streptococcus pneumoniae TIGR4

73.445

99.052

0.727
  cinA Streptococcus mitis NCTC 12261

73.445

99.052

0.727
  cinA Streptococcus pneumoniae Rx1

73.206

99.052

0.725
  cinA Streptococcus pneumoniae R6

73.206

99.052

0.725
  cinA Streptococcus pneumoniae D39

72.967

99.052

0.723
  cinA Streptococcus mutans UA159

71.395

100

0.716
  cinA Streptococcus suis isolate S10

53.846

98.578

0.531
  cinA Bacillus subtilis subsp. subtilis str. 168

46.172

99.052

0.457

Multiple sequence alignment