Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   SIR_RS14475 Genome accession   NC_022246
Coordinates   949465..950166 (-) Length   233 a.a.
NCBI ID   WP_003072980.1    Uniprot ID   A0A3R9KV56
Organism   Streptococcus intermedius B196     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 944465..955166
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS14455 (SIR_0926) rnc 945862..946560 (-) 699 WP_021002810.1 ribonuclease III -
  SIR_RS14460 (SIR_0927) - 946947..947306 (-) 360 WP_003072977.1 YbaN family protein -
  SIR_RS14465 (SIR_0928) vicX 947315..948118 (-) 804 WP_003075634.1 MBL fold metallo-hydrolase Regulator
  SIR_RS14470 (SIR_0929) micB 948120..949472 (-) 1353 WP_003072979.1 cell wall metabolism sensor histidine kinase VicK Regulator
  SIR_RS14475 (SIR_0930) micA 949465..950166 (-) 702 WP_003072980.1 response regulator YycF Regulator
  SIR_RS14480 (SIR_0931) - 950464..950805 (-) 342 WP_021002811.1 hypothetical protein -
  SIR_RS14485 (SIR_0932) - 950832..952145 (-) 1314 WP_003072983.1 glycosyltransferase family 4 protein -
  SIR_RS14490 (SIR_0933) - 952147..953145 (-) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  SIR_RS14495 (SIR_0934) ccpA 953238..954242 (-) 1005 WP_020998737.1 catabolite control protein A Regulator

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26851.80 Da        Isoelectric Point: 4.6824

>NTDB_id=61881 SIR_RS14475 WP_003072980.1 949465..950166(-) (micA) [Streptococcus intermedius B196]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALELFEAERPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=61881 SIR_RS14475 WP_003072980.1 949465..950166(-) (micA) [Streptococcus intermedius B196]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGATGGTCGTGAAGCGTTAGAGCTGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGATTTGA
TGTTGCCTGAAATAGATGGCTTAGAGGTAGCGCGAACGATTCGGAAAACGAGCAATGTACCAATCATCGTTCTGTCTGCT
AAAGATAGCGAATTTGATAAAGTCATTGGTCTCGAAATCGGCGCAGATGACTATATGACAAAGCCGTTTTCTAATCGTGA
ATTACAGGCGCGTGTCAAAGCTATTTTACGTCGTACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCAACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACGGATGCTTTTGTTGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAATTTGAATTACTACACCACCTAGCTACACATATTGGTCAAGTGATGACGCGTGAACACCTACTAGAAACAGTATG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTAACGATTCGCCGTTTGAGGGAAAAAATTGAAGATATTCCTA
GCCGCCCAGAGTATATTTTAACACGGCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KV56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.348

98.712

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361

Multiple sequence alignment