Detailed information NTG0061880

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SIR_RS14470
• Genome accession: NC_022246
• Coordinates: 948120..949472 (-)
• Length: 450 a.a.
• NCBI ID: WP_003072979.1
• Uniprot ID: -
• Organism: Streptococcus intermedius B196
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 943120..954472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SIR_RS14455 (SIR_0926)	rnc	945862..946560 (-)	699	WP_021002810.1	ribonuclease III	-
SIR_RS14460 (SIR_0927)	-	946947..947306 (-)	360	WP_003072977.1	YbaN family protein	-
SIR_RS14465 (SIR_0928)	vicX	947315..948118 (-)	804	WP_003075634.1	MBL fold metallo-hydrolase	Regulator
SIR_RS14470 (SIR_0929)	micB	948120..949472 (-)	1353	WP_003072979.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SIR_RS14475 (SIR_0930)	micA	949465..950166 (-)	702	WP_003072980.1	response regulator YycF	Regulator
SIR_RS14480 (SIR_0931)	-	950464..950805 (-)	342	WP_021002811.1	hypothetical protein	-
SIR_RS14485 (SIR_0932)	-	950832..952145 (-)	1314	WP_003072983.1	glycosyltransferase family 4 protein	-
SIR_RS14490 (SIR_0933)	-	952147..953145 (-)	999	WP_003072984.1	glycosyltransferase family 4 protein	-
SIR_RS14495 (SIR_0934)	ccpA	953238..954242 (-)	1005	WP_020998737.1	catabolite control protein A	Regulator

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51225.43 Da
• Isoelectric Point: 4.7207

>NTDB_id=61880 SIR_RS14470 WP_003072979.1 948120..949472(-) (micB) [Streptococcus intermedius B196]
MIDNIRQFVVSKDFVFVLLILGFILVITLLSLENRRDNVRIRQLNQKVKDLIAGDYSEVLDMQGGPEITDITNSINDLSE
VIRLTHENLEQETKRLSSILSYMTDGVLATNRRGQIIMINDMATKQLGVKESDARKMNILKLLGIEDEYDLRDLITKVPE
LTIDSQDENGEFLSLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVSDLLSLSRIDNATSHLDIELTNFTAFITFILNRFDKIRSQNDDKKYEIIRDYPINSTW
VEIDTDKMTQVIDNIINNAIKYSPDGGKITVSMKTTETQMILSISDEGLGIPKKDLPKIFDRFYRVDKARSRAQGGSGLG
LAIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKEAVKDDDWEEDGLEG

Nucleotide

• Length: 1353 bp

>NTDB_id=61880 SIR_RS14470 WP_003072979.1 948120..949472(-) (micB) [Streptococcus intermedius B196]
ATGATTGATAATATAAGACAATTTGTCGTATCAAAAGATTTTGTATTTGTCCTACTCATTTTAGGATTTATTTTGGTCAT
TACGTTGCTGTCCTTGGAAAATCGACGTGATAATGTTCGTATTCGCCAATTGAATCAAAAAGTGAAAGACTTAATTGCGG
GAGATTATTCAGAAGTTTTAGATATGCAAGGTGGTCCAGAAATCACTGATATTACCAATAGTATCAATGATTTATCTGAA
GTGATTCGCTTAACGCATGAAAACTTAGAACAAGAAACTAAGCGGTTATCAAGTATCTTGTCCTACATGACGGACGGTGT
CCTTGCGACCAATCGTCGTGGGCAAATTATCATGATTAATGATATGGCGACCAAGCAGTTGGGAGTCAAGGAATCTGATG
CACGAAAGATGAATATCTTAAAACTGTTAGGGATTGAAGATGAATATGATTTACGGGACTTGATTACGAAAGTTCCAGAG
CTGACCATTGATTCACAGGATGAAAATGGAGAATTTTTAAGCTTGCGTGTTCGCTTTGCCTTGATTCGTCGAGAGTCAGG
CTTTATTTCTGGGTTGGTTGCAGTGTTGCATGATACAACGGAGCAGGAAAAAGAGGAACGTGAGCGGAGACTATTTGTTT
CTAATGTCAGTCATGAATTGCGTACTCCCTTGACCAGTGTCAAGTCTTATCTGGAAGCATTAGATGAAGGCGCTTTGTCT
GAGCCAGTTGCGCCAGATTTCATCAAGGTTTCGTTAGATGAAACCAATCGGATGATGCGAATGGTTTCGGACTTACTGAG
TTTGTCGCGGATTGATAATGCGACTAGCCATTTGGATATTGAACTGACAAATTTTACAGCTTTCATCACATTTATTTTGA
ATCGTTTTGACAAGATTAGAAGTCAGAACGATGATAAAAAGTACGAAATTATCCGAGATTATCCAATTAATTCTACTTGG
GTCGAAATTGATACAGATAAAATGACACAAGTTATTGATAATATTATCAATAATGCCATTAAATATTCTCCTGATGGTGG
TAAGATTACGGTGAGTATGAAAACAACTGAGACTCAAATGATTTTATCTATATCAGATGAAGGTTTAGGAATTCCCAAAA
AAGATTTACCAAAAATTTTTGATCGATTTTATCGTGTAGACAAAGCGAGAAGTCGTGCACAAGGTGGATCGGGACTGGGC
TTGGCCATTGCTAAAGAAATTATCAAGCAGCATAACGGTTTTATCTGGGCGAAGAGTGAATATGGTAAAGGATCGACATT
TACAATCGTTCTGCCTTATGACAAAGAAGCTGTCAAAGATGATGATTGGGAAGAAGATGGATTAGAAGGATAG

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	81.549	97.556	0.796
vicK	Streptococcus mutans UA159	71.149	90.889	0.647