Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccpA   Type   Regulator
Locus tag   SIR_RS14495 Genome accession   NC_022246
Coordinates   953238..954242 (-) Length   334 a.a.
NCBI ID   WP_020998737.1    Uniprot ID   D6RVW8
Organism   Streptococcus intermedius B196     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 948238..959242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SIR_RS14475 (SIR_0930) micA 949465..950166 (-) 702 WP_003072980.1 response regulator YycF Regulator
  SIR_RS14480 (SIR_0931) - 950464..950805 (-) 342 WP_021002811.1 hypothetical protein -
  SIR_RS14485 (SIR_0932) - 950832..952145 (-) 1314 WP_003072983.1 glycosyltransferase family 4 protein -
  SIR_RS14490 (SIR_0933) - 952147..953145 (-) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  SIR_RS14495 (SIR_0934) ccpA 953238..954242 (-) 1005 WP_020998737.1 catabolite control protein A Regulator
  SIR_RS14500 (SIR_0935) - 954505..955587 (+) 1083 WP_021002812.1 M24 family metallopeptidase -
  SIR_RS14505 (SIR_0936) - 955854..956435 (-) 582 WP_021002813.1 class I SAM-dependent methyltransferase -
  SIR_RS14510 (SIR_0937) galE 956754..957773 (-) 1020 WP_020998739.1 UDP-glucose 4-epimerase GalE -
  SIR_RS14515 (SIR_0938) rfbB 957808..958854 (-) 1047 WP_021002814.1 dTDP-glucose 4,6-dehydratase -

Sequence

Protein


Download         Length: 334 a.a.        Molecular weight: 36810.90 Da        Isoelectric Point: 5.5316

>NTDB_id=61882 SIR_RS14495 WP_020998737.1 953238..954242(-) (ccpA) [Streptococcus intermedius B196]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVECLAKGNRKIAFVSGPLVDDINGKIRLAGYKEALKKAKCSYSEGLVFESKYSYDDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKGVNVPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERCSTRK

Nucleotide


Download         Length: 1005 bp        

>NTDB_id=61882 SIR_RS14495 WP_020998737.1 953238..954242(-) (ccpA) [Streptococcus intermedius B196]
ATGAACACAGACGATACTGTAACAATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTAGT
AAACGGTAATAAAAATGTAAAGGAAAACACAAGAAAAAAAGTCTTAGAAGTCATTGACCGCCTTGACTATCGACCAAATG
CGGTAGCACGTGGACTTGCCAGCAAGAAAACGACTACAGTAGGAGTTGTCATTCCAAACATCACTAGCAGTTATTTTGCG
ACACTTGCGAAAGGAATTGATGATATTGCAGAGATGTATAAGTATAATATTGTCCTAGCTAATAGTGATGAAGATGATGA
CAAGGAAGTCTCTGTTGTTAATACGCTGTTTTCAAAGCAAGTAGATGGTATTATCTTTATGGGTTATCATCTGACAGAAA
AAATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCAGTTGTACTTGCAGGAACAGTTGACGTTGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCGGTAGAATGTCTTGCAAAAGGCAACCGAAAAATTGCTTTTGTAAG
TGGACCTTTGGTAGATGATATTAATGGTAAGATTCGCTTGGCTGGCTACAAAGAAGCTTTGAAAAAAGCAAAATGTTCTT
ATAGCGAAGGGCTAGTCTTTGAGTCTAAATATAGTTATGATGATGGTTATCAATTAGCAGAACGCGTTATTGCTTCTAAA
GCAACAGCAGCTTTTGTGACTGGTGATGAGCTGGCAGCTGGACTGTTGAATGGTTTATCAGATAAAGGTGTGAATGTACC
AGAAGATTTTGAAATCATTACTAGTGACGATTCTCAGGTAGCACGTTTTACTCGCCCAAATTTGACAACTATTGGTCAGC
CTTTGTATGACCTTGGTGCAATTAGTATGCGTATGTTGACAAAGATTATGCACAAAGAAGAATTAGAAGAACGCGAAGTG
GTATTGGCACATGGTCTGATTGAGCGTTGTTCAACAAGGAAATAA

Domains

Predicted by InterproScan.

Bacterial regulatory proteins, lacI family (LacI)

(8-53)

Periplasmic binding protein-like domain (Peripla_BP_3)

(176-332)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D6RVW8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccpA Streptococcus gordonii str. Challis substr. CH1

90.419

100

0.904
  ccpA Streptococcus pneumoniae D39

88.623

100

0.886
  ccpA Lactococcus lactis subsp. lactis strain DGCC12653

58.006

99.102

0.575

Multiple sequence alignment