Detailed information NTG0061676

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: SANR_RS05275
• Genome accession: NC_022239
• Coordinates: 1066223..1067065 (-)
• Length: 280 a.a.
• NCBI ID: WP_003034514.1
• Uniprot ID: I0SJ02
• Organism: Streptococcus anginosus C238
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 1061223..1072065

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SANR_RS05260 (SANR_1031)	-	1061427..1062251 (-)	825	WP_003034490.1	alpha/beta hydrolase	-
SANR_RS05265 (SANR_1032)	trmFO	1062383..1063717 (-)	1335	WP_003034472.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
SANR_RS11140	-	1063891..1064028 (-)	138	Protein_1022	phosphoribosylanthranilate isomerase	-
SANR_RS05270 (SANR_1033)	topA	1064044..1066137 (-)	2094	WP_100207875.1	type I DNA topoisomerase	-
SANR_RS05275 (SANR_1034)	dprA/cilB/dalA	1066223..1067065 (-)	843	WP_003034514.1	DNA-processing protein DprA	Machinery gene
SANR_RS05280 (SANR_1035)	-	1067148..1067704 (-)	557	Protein_1025	sugar O-acetyltransferase	-
SANR_RS05285 (SANR_1036)	-	1067694..1068522 (-)	829	Protein_1026	PRD domain-containing protein	-
SANR_RS05290 (SANR_1037)	-	1068519..1069301 (-)	783	WP_003034469.1	ribonuclease HII	-
SANR_RS05295 (SANR_1038)	ylqF	1069288..1070139 (-)	852	WP_003034464.1	ribosome biogenesis GTPase YlqF	-
SANR_RS05300 (SANR_1039)	-	1070257..1071174 (-)	918	WP_020999610.1	MBL fold metallo-hydrolase	-

Sequence

Protein

• Length: 280 a.a.
• Molecular weight: 31111.61 Da
• Isoelectric Point: 5.2196

>NTDB_id=61676 SANR_RS05275 WP_003034514.1 1066223..1067065(-) (dprA/cilB/dalA) [Streptococcus anginosus C238]
MDNFDIYKLKEAGLTNQQVINVLSYAEIQEKELSVKDMAVVSECRNPALFIEKYLQLDDDLLRQEFEKFPSFSILDDVYP
WDLSEIYNPPVLLFYKGNLDLLKLPKVAVVGSRNSSRVGSQSVQKIVKELNNELVIVSGLARGIDTSAHMAALQNGGRTI
AVIGTGLDVFYPRANKKLQSYLGEHHLVLSEYGSEAEPLKFHFPERNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGR
DVFAIPGSILDGRSDGCHHLIQEGAKCVTSGADVLSEFQF

Nucleotide

• Length: 843 bp

>NTDB_id=61676 SANR_RS05275 WP_003034514.1 1066223..1067065(-) (dprA/cilB/dalA) [Streptococcus anginosus C238]
ATGGATAATTTTGATATTTATAAATTAAAAGAAGCTGGCTTGACCAATCAGCAGGTCATCAATGTTCTCTCGTATGCTGA
GATACAAGAAAAAGAATTATCGGTAAAAGATATGGCAGTTGTTTCAGAATGCCGCAATCCTGCTCTTTTCATTGAAAAAT
ATCTGCAGCTAGATGATGATTTATTACGTCAAGAATTTGAAAAATTTCCGTCTTTTTCTATCTTGGATGATGTGTATCCT
TGGGATTTGAGCGAAATTTACAATCCACCCGTTCTTCTTTTCTACAAAGGAAACTTAGATTTATTGAAATTACCGAAAGT
AGCCGTTGTGGGAAGTCGGAATAGTAGCCGAGTAGGTAGTCAATCCGTTCAAAAGATTGTTAAAGAGCTAAACAATGAAT
TGGTTATCGTGAGTGGTTTAGCACGCGGAATTGATACCTCGGCTCACATGGCAGCATTGCAAAATGGTGGTCGAACAATT
GCAGTTATCGGAACGGGTCTAGACGTTTTTTATCCAAGAGCGAATAAAAAACTCCAATCGTATTTGGGAGAACATCATCT
AGTACTTAGTGAATATGGTTCTGAAGCAGAGCCATTAAAATTTCATTTTCCAGAGCGTAATCGGATTATAGCAGGATTGT
GCAGAGGGGTTATTGTTGCTGAAGCCAAAATGCGCTCAGGAAGTTTAATTACTTGTGAGCGCGCAATGGAAGAAGGACGA
GATGTGTTTGCTATTCCAGGGTCAATTTTAGACGGCAGAAGTGATGGCTGTCATCATTTGATTCAAGAGGGTGCAAAGTG
TGTCACATCAGGCGCTGACGTACTTTCTGAATTCCAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-60)

• DNA recombination-mediator protein A (DNA_processg_A) (73-269)

3D structure

• AlphaFold DB: I0SJ02

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	76.429	100	0.764
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae D39	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae R6	76.071	100	0.761
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	76.071	100	0.761
dprA/cilB/dalA	Streptococcus mitis SK321	75.714	100	0.757
dprA	Streptococcus mutans UA159	65	100	0.65
dprA	Lactococcus lactis subsp. cremoris KW2	57.857	100	0.579
dprA	Staphylococcus aureus N315	37.589	100	0.379
dprA	Legionella pneumophila strain ERS1305867	43.983	86.071	0.379
dprA	Staphylococcus aureus MW2	37.367	100	0.375