Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   NPS16_RS02915 Genome accession   NZ_CP101986
Coordinates   604216..604896 (+) Length   226 a.a.
NCBI ID   WP_002265385.1    Uniprot ID   -
Organism   Streptococcus mutans strain COCC33-14     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 599216..609896
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NPS16_RS02895 (NPS16_02895) - 600588..601607 (-) 1020 WP_002275179.1 GIY-YIG nuclease family protein -
  NPS16_RS02900 (NPS16_02900) - 601653..602165 (-) 513 WP_258969077.1 HXXEE domain-containing protein -
  NPS16_RS02905 (NPS16_02905) - 602250..603185 (-) 936 WP_002269713.1 polysaccharide deacetylase family protein -
  NPS16_RS02910 (NPS16_02910) - 603324..604076 (+) 753 WP_002265384.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  NPS16_RS02915 (NPS16_02915) comEA/celA/cilE 604216..604896 (+) 681 WP_002265385.1 helix-hairpin-helix domain-containing protein Machinery gene
  NPS16_RS02920 (NPS16_02920) comEC/celB 604886..607120 (+) 2235 WP_082999655.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  NPS16_RS02925 (NPS16_02925) - 607306..607932 (+) 627 WP_082999654.1 DUF805 domain-containing protein -
  NPS16_RS02930 (NPS16_02930) holA 608100..609140 (+) 1041 WP_082999653.1 DNA polymerase III subunit delta -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 24559.88 Da        Isoelectric Point: 7.0283

>NTDB_id=613834 NPS16_RS02915 WP_002265385.1 604216..604896(+) (comEA/celA/cilE) [Streptococcus mutans strain COCC33-14]
MVDEFLDKLKEKKNVFALVGGLVVLLGLGVYFFFPSSNKQEDSLARLKEQSLQVTTKTGKESQKKTQVTTAKSTITVDIK
GAVKHEGVYTLPIDSRIDDVIEKAGGFSEKADRKSVNLAQKLQDEAVIYVAAIGENISVIRDSQEGKTSQADKANTKETS
VKGKVNLNTATLADLQTISGIGEKKAQDILDYREANGGFKSVDDLKNISGIGDKTFEKLKDLVSVD

Nucleotide


Download         Length: 681 bp        

>NTDB_id=613834 NPS16_RS02915 WP_002265385.1 604216..604896(+) (comEA/celA/cilE) [Streptococcus mutans strain COCC33-14]
ATGGTTGACGAATTTTTAGATAAACTCAAGGAAAAGAAAAATGTTTTTGCTCTAGTTGGTGGTCTTGTAGTCTTACTGGG
TCTGGGTGTTTATTTCTTTTTTCCTTCTTCCAATAAGCAGGAAGACAGTCTGGCTCGTTTAAAGGAACAATCCCTTCAGG
TAACCACAAAGACTGGCAAAGAAAGTCAAAAGAAGACGCAGGTGACGACTGCCAAATCAACAATAACTGTTGATATTAAA
GGAGCTGTTAAGCATGAGGGCGTCTATACTTTACCGATTGACAGTCGTATTGATGATGTAATAGAAAAAGCGGGAGGTTT
TTCTGAAAAGGCTGATCGCAAATCTGTTAATCTGGCTCAAAAATTACAAGACGAAGCAGTTATTTATGTGGCAGCTATTG
GTGAGAATATTAGTGTCATTAGGGATTCTCAAGAAGGTAAAACCAGTCAGGCAGATAAGGCAAATACTAAAGAAACTTCG
GTAAAAGGTAAGGTTAATCTTAATACTGCCACTTTGGCTGATTTACAGACTATTTCTGGAATCGGTGAGAAGAAAGCTCA
GGATATTCTTGATTACCGTGAAGCCAATGGAGGTTTTAAGTCAGTGGATGATTTGAAAAATATTTCAGGGATTGGCGATA
AAACATTTGAGAAGTTAAAGGATTTAGTCAGTGTTGATTAG

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(163-223)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

42.06

100

0.434
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

41.631

100

0.429
  comEA/celA/cilE Streptococcus pneumoniae D39

41.202

100

0.425
  comEA/celA/cilE Streptococcus pneumoniae Rx1

41.202

100

0.425
  comEA/celA/cilE Streptococcus pneumoniae R6

41.202

100

0.425
  comEA Lactococcus lactis subsp. cremoris KW2

42.478

100

0.425
  comEA/celA/cilE Streptococcus mitis SK321

40.343

100

0.416
  comEA Streptococcus thermophilus LMD-9

57.143

68.142

0.389
  comEA Latilactobacillus sakei subsp. sakei 23K

35.537

100

0.381