Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   NMK59_RS16635 Genome accession   NZ_CP101302
Coordinates   3279974..3280630 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain 2000-3039     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3274974..3285630
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMK59_RS16595 (NMK59_16595) - 3275484..3275744 (+) 261 WP_000488107.1 ogr/Delta-like zinc finger family protein -
  NMK59_RS16600 (NMK59_16600) - 3275934..3276074 (+) 141 WP_000078920.1 Hok/Gef family protein -
  NMK59_RS16605 (NMK59_16605) - 3276264..3276545 (-) 282 WP_071529678.1 hypothetical protein -
  NMK59_RS16625 (NMK59_16625) pgsA 3277540..3278088 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  NMK59_RS16630 (NMK59_16630) uvrC 3278145..3279977 (-) 1833 WP_001283424.1 excinuclease ABC subunit UvrC Machinery gene
  NMK59_RS16635 (NMK59_16635) letA 3279974..3280630 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  NMK59_RS28255 - 3280772..3280843 (+) 72 Protein_3281 transcriptional regulator -
  NMK59_RS16640 (NMK59_16640) yecU 3280926..3281102 (+) 177 WP_000590347.1 protein YecU -
  NMK59_RS16645 (NMK59_16645) yecF 3281089..3281313 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  NMK59_RS16650 (NMK59_16650) sdiA 3281380..3282102 (-) 723 WP_001154271.1 transcriptional regulator SdiA -
  NMK59_RS16655 (NMK59_16655) tcyN 3282332..3283084 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  NMK59_RS16660 (NMK59_16660) tcyL 3283081..3283749 (-) 669 WP_001158206.1 cystine ABC transporter permease -
  NMK59_RS16665 (NMK59_16665) dcyD 3283764..3284750 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=610201 NMK59_RS16635 WP_000611335.1 3279974..3280630(-) (letA) [Escherichia coli strain 2000-3039]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=610201 NMK59_RS16635 WP_000611335.1 3279974..3280630(-) (letA) [Escherichia coli strain 2000-3039]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTTGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486