Detailed information NTG0609937

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: I6G24_RS04050
• Genome accession: NZ_CP084189
• Coordinates: 747713..748561 (-)
• Length: 282 a.a.
• NCBI ID: WP_023164171.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FDAARGOS_867
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 742713..753561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G24_RS04035 (I6G24_04030)	xerS	742790..743860 (+)	1071	WP_003131037.1	tyrosine recombinase XerS	-
I6G24_RS04040 (I6G24_04035)	trmFO	743905..745248 (-)	1344	WP_003131150.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
I6G24_RS04045 (I6G24_04040)	topA	745320..747452 (-)	2133	WP_003131148.1	type I DNA topoisomerase	-
I6G24_RS04050 (I6G24_04045)	dprA	747713..748561 (-)	849	WP_023164171.1	DNA-processing protein DprA	Machinery gene
I6G24_RS04055 (I6G24_04050)	-	748707..749087 (-)	381	WP_023164170.1	RidA family protein	-
I6G24_RS04060 (I6G24_04055)	budA	749128..749838 (-)	711	WP_003131140.1	acetolactate decarboxylase	-
I6G24_RS04065 (I6G24_04060)	ilvA	749954..751204 (-)	1251	WP_023164169.1	threonine ammonia-lyase IlvA	-
I6G24_RS04070 (I6G24_04065)	ilvC	751260..752282 (-)	1023	WP_003131136.1	ketol-acid reductoisomerase	-
I6G24_RS04075 (I6G24_04070)	ilvN	752328..752804 (-)	477	WP_010905839.1	acetolactate synthase small subunit	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 32149.20 Da
• Isoelectric Point: 9.5086

>NTDB_id=609937 I6G24_RS04050 WP_023164171.1 747713..748561(-) (dprA) [Lactococcus lactis strain FDAARGOS_867]
MITNFDLYRWKKASMTNLGVNKLLKFFHRYDKKISLRQMGQVAQLKSIPNFIEQYKNQDVSKLREEYKIYPSFSLLDEIY
PERLKEIYNPPVLLFYQGDIRLLKTPKLAFVGSRQASSQGIKAVQKIVTELNQNFTIVSGLAKGIDTASHLSAIKNKIPT
IAVIGTGLDIFYPLENRKIQEYLAKNQLILSEYSVGEKPLRYHFPERNRIIAGLSHGVVVIEAKLRSGSLITCERALEEG
RDIFAVPGNIADGFSDGCNHLIQQGAKLIYQAQDILEEYLYD

Nucleotide

• Length: 849 bp

>NTDB_id=609937 I6G24_RS04050 WP_023164171.1 747713..748561(-) (dprA) [Lactococcus lactis strain FDAARGOS_867]
ATGATAACAAATTTTGATTTATATCGTTGGAAAAAAGCTAGCATGACCAATTTAGGAGTAAATAAACTTTTAAAATTTTT
TCATAGATATGATAAAAAAATAAGTTTAAGACAAATGGGACAAGTAGCACAACTTAAATCAATTCCCAACTTTATTGAAC
AATATAAAAATCAAGACGTAAGTAAACTGAGAGAAGAGTATAAAATATACCCATCATTTTCTCTTCTTGATGAAATTTAT
CCCGAAAGGCTCAAGGAAATTTACAATCCACCGGTTCTATTATTTTATCAAGGAGATATAAGACTCTTAAAAACTCCTAA
ATTAGCTTTTGTTGGTAGTCGACAAGCAAGCTCACAAGGAATTAAAGCCGTTCAAAAAATTGTGACAGAGTTGAACCAAA
ATTTTACGATTGTCAGCGGACTCGCTAAAGGAATTGATACAGCAAGTCATCTCTCTGCCATTAAAAATAAAATCCCTACA
ATTGCAGTTATCGGTACAGGCTTAGATATCTTTTATCCTTTAGAAAATCGAAAAATTCAAGAATATCTTGCTAAAAACCA
ACTCATACTATCAGAATATTCAGTCGGAGAAAAACCACTTCGCTATCATTTTCCTGAACGCAATCGTATCATTGCGGGAC
TTTCACATGGTGTAGTAGTGATAGAAGCAAAGTTACGAAGTGGTAGTTTAATTACTTGTGAACGCGCTCTGGAAGAAGGA
AGAGATATTTTCGCTGTACCAGGAAACATAGCAGATGGATTTTCAGATGGCTGTAATCATCTAATACAACAAGGAGCAAA
ATTAATCTATCAAGCCCAAGATATCTTAGAAGAATATTTGTATGATTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (2-63)

• DNA recombination-mediator protein A (DNA_processg_A) (76-270)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Lactococcus lactis subsp. cremoris KW2	86.525	100	0.865
dprA	Streptococcus mutans UA159	59.712	98.582	0.589
dprA/cilB/dalA	Streptococcus mitis SK321	54.286	99.291	0.539
dprA/cilB/dalA	Streptococcus pneumoniae R6	53.571	99.291	0.532
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	53.571	99.291	0.532
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	53.571	99.291	0.532
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	53.571	99.291	0.532
dprA/cilB/dalA	Streptococcus pneumoniae D39	53.571	99.291	0.532
dprA	Bacillus subtilis subsp. subtilis str. 168	40	97.518	0.39
dprA	Legionella pneumophila strain ERS1305867	39.13	97.872	0.383
dprA	Haemophilus influenzae Rd KW20	38.889	95.745	0.372
dprA	Latilactobacillus sakei subsp. sakei 23K	38.745	96.099	0.372