Detailed information NTG0602570

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: K8B76_RS09410
• Genome accession: NZ_CP082820
• Coordinates: 1874277..1874738 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250539.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SCAID PHRX1-2021
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1869277..1879738

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K8B76_RS09380 (K8B76_09380)	-	1869582..1870406 (-)	825	WP_000727909.1	membrane protein insertase YidC	-
K8B76_RS09385 (K8B76_09385)	rnpA	1870381..1870752 (-)	372	WP_000739246.1	ribonuclease P protein component	-
K8B76_RS10890	-	1870769..1870900 (-)	132	WP_000768904.1	hypothetical protein	-
K8B76_RS09390 (K8B76_09390)	-	1870901..1872091 (-)	1191	WP_000167769.1	acetate kinase	-
K8B76_RS09395 (K8B76_09395)	comYH	1872142..1873095 (-)	954	WP_000345080.1	class I SAM-dependent methyltransferase	Machinery gene
K8B76_RS09400 (K8B76_09400)	-	1873156..1873750 (-)	595	Protein_1851	class I SAM-dependent methyltransferase	-
K8B76_RS09405 (K8B76_09405)	comGG/cglG	1873853..1874299 (-)	447	WP_001842224.1	competence type IV pilus minor pilin ComGG	Machinery gene
K8B76_RS09410 (K8B76_09410)	comGF/cglF	1874277..1874738 (-)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
K8B76_RS09415 (K8B76_09415)	comGE/cglE	1874701..1875003 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
K8B76_RS09420 (K8B76_09420)	comGD/cglD	1874966..1875370 (-)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
K8B76_RS09425 (K8B76_09425)	comGC/cglC	1875363..1875689 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
K8B76_RS09430 (K8B76_09430)	comGB/cglB	1875691..1876707 (-)	1017	WP_078102766.1	competence type IV pilus assembly protein ComGB	Machinery gene
K8B76_RS09435 (K8B76_09435)	comGA/cglA/cilD	1876655..1877596 (-)	942	WP_000249571.1	competence type IV pilus ATPase ComGA	Machinery gene
K8B76_RS09440 (K8B76_09440)	-	1877672..1878037 (-)	366	WP_000286415.1	DUF1033 family protein	-
K8B76_RS09445 (K8B76_09445)	-	1878188..1879246 (-)	1059	WP_000649470.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=602570 K8B76_RS09410 WP_000250539.1 1874277..1874738(-) (comGF/cglF) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQTMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVEGN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=602570 K8B76_RS09410 WP_000250539.1 1874277..1874738(-) (comGF/cglF) [Streptococcus pneumoniae strain SCAID PHRX1-2021]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAACTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAGGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915