Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   K6749_RS12605 Genome accession   NZ_CP082310
Coordinates   2727083..2728306 (+) Length   407 a.a.
NCBI ID   WP_017635918.1    Uniprot ID   A0AAW9BMM9
Organism   Vibrio alginolyticus strain HYV1     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2722083..2733306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6749_RS12585 (K6749_12505) ampD 2723139..2723690 (-) 552 WP_238970100.1 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD -
  K6749_RS12590 (K6749_12510) nadC 2723783..2724670 (+) 888 WP_042521335.1 carboxylating nicotinate-nucleotide diphosphorylase -
  K6749_RS12595 (K6749_12515) pilA 2724932..2725363 (+) 432 WP_042521333.1 prepilin-type N-terminal cleavage/methylation domain-containing protein Machinery gene
  K6749_RS12600 (K6749_12520) pilB 2725374..2727059 (+) 1686 WP_042521331.1 type IV-A pilus assembly ATPase PilB Machinery gene
  K6749_RS12605 (K6749_12525) pilC 2727083..2728306 (+) 1224 WP_017635918.1 type II secretion system F family protein Machinery gene
  K6749_RS12610 (K6749_12530) pilD 2728371..2729240 (+) 870 WP_017635919.1 A24 family peptidase Machinery gene
  K6749_RS12615 (K6749_12535) coaE 2729241..2729855 (+) 615 WP_042521328.1 dephospho-CoA kinase -
  K6749_RS12620 (K6749_12540) zapD 2729883..2730623 (+) 741 WP_042521326.1 cell division protein ZapD -
  K6749_RS12625 (K6749_12545) yacG 2730782..2730976 (+) 195 WP_017635922.1 DNA gyrase inhibitor YacG -
  K6749_RS12630 (K6749_12550) rplS 2731288..2731641 (-) 354 WP_005379971.1 50S ribosomal protein L19 -
  K6749_RS12635 (K6749_12555) trmD 2731683..2732444 (-) 762 WP_017635923.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  K6749_RS12640 (K6749_12560) rimM 2732472..2733020 (-) 549 WP_005379964.1 ribosome maturation factor RimM -
  K6749_RS12645 (K6749_12565) rpsP 2733050..2733298 (-) 249 WP_005379962.1 30S ribosomal protein S16 -

Sequence

Protein


Download         Length: 407 a.a.        Molecular weight: 45313.50 Da        Isoelectric Point: 10.3992

>NTDB_id=601237 K6749_RS12605 WP_017635918.1 2727083..2728306(+) (pilC) [Vibrio alginolyticus strain HYV1]
MKSTTPQLKNFRWKGINSSGKKTSGQTLAMTEIEVRERLDAQHIKIKKLKKSSISFLTKLSHRVKGRDITVFTRQISTML
ITGVPLVQALKLVSENHKKAEMKSILMSVTRAVEAGTPMSKAMRTASEHFDPLYTDLIATGEQSGNLAEVFERLATYREK
NEQLRAKVIKALIYPAMVVLVALGVSFIMLTKVIPEFEKMFVGFGADLPWFTRQVLDLSAWTQNWSPFIALGSISLFISA
RILSKRSDSFRLMLNRSVLKFPVLGPVLSKAAIAKFSRTLATSFTAGIPILTSLKTTSKTSGNLHYQLAIEEVYRDTAAG
MPMYVAMRNCNVFPELVLQMVMIGEESGRLDDMLNKVATIYEFEVDNTVDNLSKILEPLIIVFLGIVVGGLVTAMYLPIF
NLMSVLG

Nucleotide


Download         Length: 1224 bp        

>NTDB_id=601237 K6749_RS12605 WP_017635918.1 2727083..2728306(+) (pilC) [Vibrio alginolyticus strain HYV1]
ATGAAAAGCACTACACCACAACTTAAAAACTTCCGCTGGAAAGGCATCAACAGTTCAGGCAAAAAGACATCTGGACAAAC
CCTCGCGATGACGGAAATTGAAGTACGCGAGCGTCTAGACGCACAGCACATCAAGATCAAGAAGTTAAAGAAAAGCAGTA
TCTCGTTTCTCACTAAACTCAGCCATCGCGTGAAAGGCAGAGACATCACGGTGTTTACCCGTCAGATTTCGACGATGTTG
ATAACCGGTGTACCCTTAGTTCAGGCTTTAAAATTGGTCTCAGAAAATCATAAAAAAGCAGAGATGAAATCCATTTTGAT
GAGCGTGACACGCGCCGTTGAAGCGGGGACGCCCATGTCAAAAGCCATGCGCACTGCAAGTGAACACTTTGACCCACTCT
ATACCGATCTTATCGCCACAGGTGAGCAATCCGGTAACTTAGCAGAAGTATTCGAGCGCTTAGCCACCTACCGAGAAAAA
AATGAGCAGCTTCGTGCGAAAGTGATCAAAGCACTGATTTACCCAGCCATGGTAGTGCTAGTAGCGTTAGGAGTGTCGTT
TATCATGCTCACCAAAGTCATTCCCGAGTTTGAAAAAATGTTTGTTGGTTTTGGTGCTGACTTACCGTGGTTTACCAGGC
AAGTGTTAGATCTTTCCGCCTGGACACAAAACTGGAGCCCATTTATAGCACTAGGCTCTATCAGTCTATTCATCTCAGCG
AGAATCCTCTCTAAGCGTTCAGATTCTTTTCGCTTAATGCTCAATCGCTCTGTGCTTAAATTTCCTGTCCTCGGGCCCGT
ATTATCAAAAGCCGCTATCGCCAAATTTAGTCGAACACTCGCCACAAGCTTTACAGCGGGTATTCCAATTCTAACCAGTT
TAAAAACCACATCAAAAACCTCAGGAAACTTGCACTATCAACTCGCCATAGAAGAAGTTTACCGTGATACCGCCGCAGGT
ATGCCAATGTATGTTGCCATGCGTAACTGTAATGTGTTCCCTGAATTAGTGTTACAAATGGTCATGATCGGTGAAGAGTC
TGGTCGACTTGACGACATGCTCAATAAAGTTGCAACGATCTACGAGTTTGAAGTCGATAACACCGTCGACAACCTTAGTA
AAATTCTAGAGCCATTAATTATCGTTTTTTTAGGTATCGTTGTTGGCGGATTAGTGACAGCAATGTACTTGCCAATCTTT
AACTTAATGAGTGTATTGGGCTAG

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(72-195)

Type II secretion system (T2SS), protein F (T2SSF)

(276-398)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Vibrio campbellii strain DS40M4

87.224

100

0.872
  pilC Vibrio cholerae strain A1552

73.775

100

0.74
  pilC Acinetobacter baylyi ADP1

43

98.28

0.423
  pilC Acinetobacter baumannii D1279779

41.439

99.017

0.41
  pilG Neisseria gonorrhoeae MS11

40.494

99.509

0.403
  pilC Legionella pneumophila strain ERS1305867

40.295

100

0.403
  pilG Neisseria meningitidis 44/76-A

40.247

99.509

0.4
  pilC Pseudomonas stutzeri DSM 10701

40.909

97.297

0.398