Detailed information NTG0601238

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: K6749_RS12610
• Genome accession: NZ_CP082310
• Coordinates: 2728371..2729240 (+)
• Length: 289 a.a.
• NCBI ID: WP_017635919.1
• Uniprot ID: A0A2I3C9C8
• Organism: Vibrio alginolyticus strain HYV1
• Function: type IV pilus biogenesis and function (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2723371..2734240

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
K6749_RS12590 (K6749_12510)	nadC	2723783..2724670 (+)	888	WP_042521335.1	carboxylating nicotinate-nucleotide diphosphorylase	-
K6749_RS12595 (K6749_12515)	pilA	2724932..2725363 (+)	432	WP_042521333.1	prepilin-type N-terminal cleavage/methylation domain-containing protein	Machinery gene
K6749_RS12600 (K6749_12520)	pilB	2725374..2727059 (+)	1686	WP_042521331.1	type IV-A pilus assembly ATPase PilB	Machinery gene
K6749_RS12605 (K6749_12525)	pilC	2727083..2728306 (+)	1224	WP_017635918.1	type II secretion system F family protein	Machinery gene
K6749_RS12610 (K6749_12530)	pilD	2728371..2729240 (+)	870	WP_017635919.1	A24 family peptidase	Machinery gene
K6749_RS12615 (K6749_12535)	coaE	2729241..2729855 (+)	615	WP_042521328.1	dephospho-CoA kinase	-
K6749_RS12620 (K6749_12540)	zapD	2729883..2730623 (+)	741	WP_042521326.1	cell division protein ZapD	-
K6749_RS12625 (K6749_12545)	yacG	2730782..2730976 (+)	195	WP_017635922.1	DNA gyrase inhibitor YacG	-
K6749_RS12630 (K6749_12550)	rplS	2731288..2731641 (-)	354	WP_005379971.1	50S ribosomal protein L19	-
K6749_RS12635 (K6749_12555)	trmD	2731683..2732444 (-)	762	WP_017635923.1	tRNA (guanosine(37)-N1)-methyltransferase TrmD	-
K6749_RS12640 (K6749_12560)	rimM	2732472..2733020 (-)	549	WP_005379964.1	ribosome maturation factor RimM	-
K6749_RS12645 (K6749_12565)	rpsP	2733050..2733298 (-)	249	WP_005379962.1	30S ribosomal protein S16	-

Sequence

Protein

• Length: 289 a.a.
• Molecular weight: 32563.76 Da
• Isoelectric Point: 6.8450

>NTDB_id=601238 K6749_RS12610 WP_017635919.1 2728371..2729240(+) (pilD) [Vibrio alginolyticus strain HYV1]
MEVFQYYPWLFVVFATIFGLIVGSFLNVVIYRLPKIMELEWRRECAESFPEYKIEPPKEVLTLSVPRSSCQKCATPIRIR
DNIPVISWLLLKGKCHNCQATISARYPLIELLTAFCSGFIAYYFGFSYFTVALLFFTFILIAATFIDLDTMLLPDQLTLP
LTWAGIALALVEISPVTLQDSVIGAIAGYLCLWSVYWGFKLLTGKEGMGYGDFKLLAALGAWLGWQSLPMIILLSSVVGI
VFGIIQLRLQKQGIEKAFPFGPYLAIAGWISLIWGDQILNWYFTSVLGV

Nucleotide

• Length: 870 bp

>NTDB_id=601238 K6749_RS12610 WP_017635919.1 2728371..2729240(+) (pilD) [Vibrio alginolyticus strain HYV1]
ATGGAAGTATTCCAGTACTACCCTTGGCTATTCGTTGTGTTTGCCACCATCTTCGGTCTGATCGTGGGTAGCTTCCTCAA
TGTGGTTATTTATCGACTACCTAAAATCATGGAACTAGAATGGCGACGCGAATGTGCCGAGTCATTTCCTGAATACAAAA
TAGAACCTCCTAAAGAAGTGCTGACCTTGAGCGTTCCACGCTCCTCCTGCCAGAAATGCGCAACACCGATACGTATTCGC
GACAACATTCCTGTGATTAGCTGGCTGCTTTTAAAAGGCAAATGTCACAACTGTCAGGCAACCATTAGTGCACGCTATCC
ACTGATTGAACTGCTCACCGCGTTCTGTTCAGGCTTTATCGCTTATTACTTTGGTTTTAGTTACTTTACCGTTGCCCTAC
TCTTTTTTACTTTTATCTTAATCGCCGCAACATTTATCGATCTCGATACTATGTTGTTACCTGACCAATTAACATTACCA
TTAACTTGGGCTGGCATTGCCTTAGCATTAGTCGAAATAAGTCCTGTTACTCTACAAGATTCTGTCATTGGTGCTATTGC
TGGTTACCTATGTCTCTGGTCCGTTTACTGGGGCTTTAAGCTACTTACTGGTAAAGAAGGAATGGGGTATGGTGATTTTA
AACTACTGGCGGCACTAGGAGCTTGGCTAGGTTGGCAGTCACTGCCGATGATCATTCTACTTTCTTCTGTGGTTGGCATC
GTATTTGGCATCATTCAACTACGCTTGCAAAAGCAGGGAATTGAAAAAGCTTTCCCTTTCGGTCCTTACTTAGCAATTGC
TGGTTGGATAAGCTTAATTTGGGGCGACCAGATTTTAAACTGGTACTTTACTTCAGTTCTAGGAGTGTAA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (135-244)

3D structure

• AlphaFold DB: A0A2I3C9C8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Vibrio campbellii strain DS40M4	91.349	100	0.913
pilD	Vibrio cholerae strain A1552	73.264	99.654	0.73
pilD	Acinetobacter baumannii D1279779	52.222	93.426	0.488
pilD	Acinetobacter nosocomialis M2	51.852	93.426	0.484
pilD	Neisseria gonorrhoeae MS11	47.653	95.848	0.457