Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   K6969_RS08165 Genome accession   NZ_CP082205
Coordinates   1691500..1692162 (-) Length   220 a.a.
NCBI ID   WP_024399058.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1686500..1697162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS08160 (K6969_08050) comEC/celB 1689279..1691516 (-) 2238 WP_171942589.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  K6969_RS08165 (K6969_08055) comEA/celA/cilE 1691500..1692162 (-) 663 WP_024399058.1 helix-hairpin-helix domain-containing protein Machinery gene
  K6969_RS08170 (K6969_08060) - 1692229..1692975 (-) 747 WP_171942590.1 lysophospholipid acyltransferase family protein -
  K6969_RS08175 (K6969_08065) - 1693122..1694567 (+) 1446 WP_171942591.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  K6969_RS08180 (K6969_08070) - 1694983..1695768 (+) 786 WP_171942592.1 ABC transporter ATP-binding protein -
  K6969_RS08185 (K6969_08075) - 1695781..1696710 (+) 930 WP_029178642.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23476.21 Da        Isoelectric Point: 4.1150

>NTDB_id=600056 K6969_RS08165 WP_024399058.1 1691500..1692162(-) (comEA/celA/cilE) [Streptococcus suis strain AKJ18]
MDTIKTYIEMLKEYKWQIALPAVAGLLMATFLIFSQPAKSDQTGLTDFSQPQQSSSSQEQLEEVSTEASEEPTQLVVDVK
GAVVKPGLYTLEAGARVNDAVEVAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTTSSAMSQEEKNTSLVN
LNTATETDLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVE

Nucleotide


Download         Length: 663 bp        

>NTDB_id=600056 K6969_RS08165 WP_024399058.1 1691500..1692162(-) (comEA/celA/cilE) [Streptococcus suis strain AKJ18]
ATGGATACAATCAAAACTTATATAGAAATGCTTAAAGAATACAAGTGGCAAATTGCTCTGCCAGCAGTGGCTGGCTTGCT
AATGGCGACGTTCTTAATATTCAGTCAACCAGCCAAGTCTGACCAGACAGGCCTGACTGATTTTTCACAGCCACAGCAAA
GTTCAAGTAGTCAGGAGCAGCTTGAAGAAGTCAGTACAGAAGCAAGTGAAGAGCCTACCCAGCTGGTCGTTGATGTCAAA
GGAGCGGTAGTAAAACCAGGACTGTACACCTTAGAAGCTGGTGCGCGTGTTAATGATGCAGTTGAAGTAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAAGCGGTGGTCTATGTGGCCAGCAAGG
ATGAAAATATCTCGGTGGTGGCCAGCACGACTACCAGCTCTGCTATGTCCCAAGAAGAAAAAAACACCAGTCTAGTCAAT
CTCAACACGGCGACCGAGACTGACCTGCAGACCATTTCGGGTATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAACGGTGGCTTCAAGTCGGTGGATGACCTCAACAATGTTTCGGGCATCGGCGACAAGACCATGGAAAGCATTC
GACCTTATGTCACGGTTGAGTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(155-218)

SLBB domain (SLBB)

(76-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.696

100

0.482
  comEA/celA/cilE Streptococcus mitis NCTC 12261

46.696

100

0.482
  comEA/celA/cilE Streptococcus pneumoniae Rx1

47.489

99.545

0.473
  comEA/celA/cilE Streptococcus pneumoniae D39

47.489

99.545

0.473
  comEA/celA/cilE Streptococcus pneumoniae R6

47.489

99.545

0.473
  comEA/celA/cilE Streptococcus mitis SK321

45.249

100

0.455
  comEA Streptococcus thermophilus LMD-9

60.759

71.818

0.436
  comEA Lactococcus lactis subsp. cremoris KW2

39.171

98.636

0.386