Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC/celB   Type   Machinery gene
Locus tag   K6969_RS08160 Genome accession   NZ_CP082205
Coordinates   1689279..1691516 (-) Length   745 a.a.
NCBI ID   WP_171942589.1    Uniprot ID   -
Organism   Streptococcus suis strain AKJ18     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1684279..1696516
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  K6969_RS08160 (K6969_08050) comEC/celB 1689279..1691516 (-) 2238 WP_171942589.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  K6969_RS08165 (K6969_08055) comEA/celA/cilE 1691500..1692162 (-) 663 WP_024399058.1 helix-hairpin-helix domain-containing protein Machinery gene
  K6969_RS08170 (K6969_08060) - 1692229..1692975 (-) 747 WP_171942590.1 lysophospholipid acyltransferase family protein -
  K6969_RS08175 (K6969_08065) - 1693122..1694567 (+) 1446 WP_171942591.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  K6969_RS08180 (K6969_08070) - 1694983..1695768 (+) 786 WP_171942592.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 745 a.a.        Molecular weight: 83940.85 Da        Isoelectric Point: 6.7838

>NTDB_id=600055 K6969_RS08160 WP_171942589.1 1689279..1691516(-) (comEC/celB) [Streptococcus suis strain AKJ18]
MSRLSKLPCQPLHLAILAVAAYFAVHSFSLLTIGLLSLLLLVFGFRQGKAVFIKTLPLLALCGLFFGCQKVQWEWTDQSA
PEQVATLQVIPDTIEVNGDSLSFRGRADGQTYQVFYKLASQEEQAYFQELTDLVQLEVEAEVSLPAGQRNFKGFDYQAYL
KTQGIYRTVKITAIKKIVPVQSWNVFDWLSSWRRQALVYVKTNFPAPMSHYMTGLLFGDLDSEFDQMSDLYSSLGIIHLF
ALSGMQVGFFIDKFRWMLLRLGLTKETVDKLQIPFSFVYVSLTGFSVSVVRSLVQKILGNLGLRKLDNFAVTVFVCLLIL
PRFLLTAGGVLTFTYAFLLTVFDFEDLGQVKKAAVESLSISLGILPVLMTYFYAFQPLSILLTFVFSFVFDVLLLPGLSV
IFLLSPVVQMTWVNGFFVFMEKIIVWVADLGLRPWILGKPSGVILVLLLVSLFLLYDFHRKKKWLLGLILVLALLFFITK
HPLENEVTVVDIGQGDSIFLRDMRGRTVLIDVGGRVDFAAKEAWQERSRQANAERTLIPYLHSRGVDRIDSLVLTHTDTD
HVGDVLEVAKQVQIGRIVVSPGSLTVPDFVATLKKINVPVHVVKVGDRLPIFDSYLEVLYPDGTGDGGNNDSIVLYGRLL
ETNFLFTGDLEQGELDLIATYPNLPVDVLKAGHHGSKGSSYPEFLDHIGAKIALVSAGENNRYKHPHQETLERFDNRNIQ
VYRTDQQGAIRFLGWREWQIETVRE

Nucleotide


Download         Length: 2238 bp        

>NTDB_id=600055 K6969_RS08160 WP_171942589.1 1689279..1691516(-) (comEC/celB) [Streptococcus suis strain AKJ18]
ATGTCACGGTTGAGTAAGCTCCCCTGCCAGCCCCTCCACCTAGCCATCTTAGCGGTGGCGGCCTACTTTGCAGTCCACTC
TTTTTCCCTCTTGACAATAGGCCTGCTCAGTTTGTTGTTGCTGGTCTTTGGATTTCGGCAAGGTAAGGCAGTTTTCATCA
AAACGCTGCCGCTTTTAGCCCTATGTGGTCTGTTTTTCGGATGCCAAAAGGTCCAATGGGAGTGGACAGACCAGTCAGCC
CCAGAGCAAGTGGCGACTTTGCAGGTCATTCCAGATACCATTGAAGTCAACGGGGACAGCCTGTCCTTTCGCGGTCGGGC
TGACGGACAAACCTATCAAGTTTTCTACAAATTAGCCAGTCAGGAGGAGCAGGCTTATTTTCAAGAGCTGACAGATTTGG
TCCAGCTTGAAGTGGAAGCAGAGGTCAGCCTGCCAGCTGGTCAGCGGAATTTCAAGGGTTTTGATTATCAGGCCTATCTG
AAAACACAGGGCATTTACCGAACAGTCAAGATAACTGCGATTAAGAAGATTGTCCCTGTCCAGTCATGGAATGTCTTTGA
CTGGCTATCAAGCTGGCGGAGGCAAGCCTTGGTCTATGTCAAAACCAATTTTCCGGCTCCCATGAGCCACTACATGACAG
GGCTCTTGTTTGGGGACTTGGATAGTGAGTTTGACCAGATGAGTGATCTCTATTCTAGTTTAGGAATCATTCATCTCTTT
GCCCTGTCTGGTATGCAGGTTGGATTTTTCATCGACAAGTTTCGCTGGATGTTACTGCGTTTGGGCTTGACCAAGGAAAC
GGTTGATAAATTACAAATTCCCTTTTCCTTTGTCTATGTGAGTTTGACAGGTTTTTCCGTATCGGTGGTGCGGTCCTTGG
TCCAAAAAATTCTGGGTAATCTAGGCTTGCGGAAGTTGGATAATTTTGCGGTGACAGTCTTTGTCTGTCTGCTGATTTTG
CCCCGATTTCTCTTGACAGCTGGTGGTGTCCTGACCTTTACCTATGCTTTTTTGCTGACAGTTTTTGATTTTGAAGACTT
GGGGCAGGTCAAAAAGGCTGCGGTGGAGAGCCTCAGTATTTCGCTGGGAATTTTGCCGGTGCTTATGACCTATTTCTATG
CCTTTCAGCCTTTGTCTATCCTCTTAACTTTTGTCTTTTCCTTTGTCTTTGATGTCCTGCTTTTGCCAGGTTTGTCGGTC
ATTTTTCTTTTGTCGCCAGTTGTCCAGATGACTTGGGTCAACGGATTTTTTGTCTTTATGGAGAAAATCATTGTCTGGGT
GGCTGATTTGGGATTGCGGCCTTGGATACTGGGCAAGCCGTCTGGGGTAATTCTTGTTCTCTTGCTGGTCAGCCTTTTCT
TGCTCTACGATTTCCACAGGAAAAAGAAATGGCTCTTAGGACTAATCTTGGTCCTTGCTCTGCTATTTTTCATCACTAAA
CACCCGCTGGAAAACGAGGTGACGGTGGTGGACATCGGGCAGGGGGACAGCATCTTTTTGCGGGATATGCGGGGGCGGAC
GGTCCTGATTGATGTGGGCGGACGAGTCGATTTCGCGGCCAAGGAAGCGTGGCAGGAGCGGTCTCGGCAGGCAAATGCAG
AGCGGACTTTGATTCCCTATCTGCATAGTCGGGGTGTAGATAGGATTGATAGTCTAGTGCTGACCCACACAGATACAGAC
CATGTGGGCGATGTGCTGGAAGTGGCTAAGCAGGTGCAAATTGGTCGGATTGTCGTGTCGCCGGGAAGTCTGACGGTGCC
TGACTTTGTAGCAACTCTGAAAAAAATCAATGTCCCAGTCCATGTGGTGAAAGTGGGCGACCGCTTGCCGATTTTTGACT
CCTATCTGGAAGTCCTCTACCCAGATGGGACAGGAGACGGTGGCAATAATGATTCTATTGTTCTCTACGGTCGCTTGTTG
GAAACCAACTTTCTCTTTACAGGAGATTTGGAGCAAGGGGAGTTGGACTTGATAGCAACCTATCCCAACCTGCCTGTCGA
TGTCCTCAAAGCCGGCCACCACGGCTCCAAAGGTTCTTCCTATCCTGAATTTCTAGACCATATCGGAGCCAAGATTGCTC
TGGTATCAGCAGGAGAAAACAATCGTTACAAACACCCCCACCAAGAAACCTTGGAACGATTTGACAATCGGAATATCCAA
GTCTATCGTACCGACCAGCAAGGAGCCATTCGCTTTCTAGGTTGGAGGGAGTGGCAAATTGAGACGGTGAGGGAATGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(27-175)

Competence protein (Competence)

(215-460)

Metallo-beta-lactamase superfamily (Lactamase_B)

(493-698)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC/celB Streptococcus mitis SK321

53.619

100

0.537
  comEC/celB Streptococcus mitis NCTC 12261

52.688

99.866

0.526
  comEC/celB Streptococcus pneumoniae TIGR4

51.678

100

0.517
  comEC/celB Streptococcus pneumoniae Rx1

51.544

100

0.515
  comEC/celB Streptococcus pneumoniae D39

51.544

100

0.515
  comEC/celB Streptococcus pneumoniae R6

51.544

100

0.515
  comEC Lactococcus lactis subsp. cremoris KW2

48.728

100

0.489