Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   M8286_RS05725 Genome accession   NZ_CP097577
Coordinates   1189713..1190375 (-) Length   220 a.a.
NCBI ID   WP_275600586.1    Uniprot ID   -
Organism   Streptococcus suis strain 3112     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1184713..1195375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M8286_RS05705 (M8286_05750) - 1185590..1186417 (-) 828 WP_275600584.1 hypothetical protein -
  M8286_RS05710 (M8286_05755) - 1186511..1187167 (-) 657 WP_002935353.1 CBS domain-containing protein -
  M8286_RS05715 (M8286_05760) - 1187305..1187475 (-) 171 Protein_1081 transposase -
  M8286_RS05720 (M8286_05765) comEC/celB 1187492..1189729 (-) 2238 WP_275600585.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  M8286_RS05725 (M8286_05770) comEA/celA/cilE 1189713..1190375 (-) 663 WP_275600586.1 helix-hairpin-helix domain-containing protein Machinery gene
  M8286_RS05730 (M8286_05775) - 1190442..1191188 (-) 747 WP_024407568.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  M8286_RS05735 (M8286_05780) - 1191600..1193045 (+) 1446 WP_275600587.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  M8286_RS05740 (M8286_05785) - 1193197..1193982 (+) 786 WP_024385481.1 ABC transporter ATP-binding protein -
  M8286_RS05745 (M8286_05790) - 1193995..1194924 (+) 930 WP_253214632.1 ABC transporter substrate-binding protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23218.00 Da        Isoelectric Point: 4.2255

>NTDB_id=595729 M8286_RS05725 WP_275600586.1 1189713..1190375(-) (comEA/celA/cilE) [Streptococcus suis strain 3112]
MDTLKTYIEMLKEYKWQIALPAAAGLLLTTFLIFSQPAKSDQTGLPDLPQTEQTSNSSELVEETSTEVSKVPSQLVVDVK
GAVAKPGLYTLAADARVNDAVEAAGGLTSQADPKSINLAQKLSDEAVVYVASKDENISVVASTTASSAMSQGEKNTNLVN
LNTATEADLQTISGIGAKRAADIIAYREANGGFKSVDDLNNVSGIGDKTMESIRPYVTVD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=595729 M8286_RS05725 WP_275600586.1 1189713..1190375(-) (comEA/celA/cilE) [Streptococcus suis strain 3112]
ATGGATACGCTTAAAACTTATATTGAAATGCTTAAAGAATACAAGTGGCAGATTGCTCTGCCAGCAGCTGCAGGTTTGCT
TCTGACGACATTCTTAATATTCAGCCAACCAGCTAAGTCAGATCAAACAGGACTGCCAGATTTACCACAGACTGAACAAA
CTTCTAATAGCTCTGAGTTGGTCGAGGAAACTAGTACAGAAGTAAGTAAGGTGCCTAGCCAGCTGGTCGTCGATGTCAAA
GGAGCGGTGGCAAAGCCAGGACTTTACACTTTAGCAGCTGATGCGCGTGTTAATGATGCAGTTGAAGCAGCTGGCGGCTT
GACCAGTCAGGCAGACCCCAAGTCTATCAATCTGGCTCAGAAGCTCAGCGACGAGGCGGTGGTCTATGTGGCCAGCAAGG
ACGAAAATATCTCGGTGGTGGCTAGCACGACTGCCAGCTCTGCCATGTCCCAAGGAGAAAAAAACACTAATCTAGTCAAT
CTAAACACGGCGACCGAGGCTGACCTGCAGACCATTTCGGGCATCGGTGCCAAGCGGGCGGCGGACATTATCGCCTATCG
TGAGGCCAATGGTGGCTTCAAGTCGGTGGACGACCTCAACAATGTGTCGGGTATCGGCGACAAGACCATGGAAAGCATCC
GGCCTTATGTCACGGTCGATTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(76-130)

Helix-hairpin-helix motif (HHH_3)

(155-218)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

46.053

100

0.477
  comEA/celA/cilE Streptococcus mitis NCTC 12261

45.022

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae Rx1

46.637

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae D39

46.637

100

0.473
  comEA/celA/cilE Streptococcus pneumoniae R6

46.637

100

0.473
  comEA/celA/cilE Streptococcus mitis SK321

45.415

100

0.473
  comEA Streptococcus thermophilus LMD-9

59.477

69.545

0.414
  comEA Lactococcus lactis subsp. cremoris KW2

38.667

100

0.395
  comEA Bacillus subtilis subsp. subtilis str. 168

40.476

95.455

0.386