Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   MSA_RS01115 Genome accession   NC_021486
Coordinates   189343..190314 (+) Length   323 a.a.
NCBI ID   WP_016480231.1    Uniprot ID   -
Organism   Streptococcus agalactiae ILRI005     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 184343..195314
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MSA_RS01105 (MSA_2310) rpoC 185042..188692 (+) 3651 WP_041165643.1 DNA-directed RNA polymerase subunit beta' -
  MSA_RS01110 (MSA_2330) - 188806..189171 (+) 366 WP_016480230.1 DUF1033 family protein -
  MSA_RS01115 (MSA_2340) comYA 189343..190314 (+) 972 WP_016480231.1 competence type IV pilus ATPase ComGA Machinery gene
  MSA_RS01120 (MSA_2350) comGB 190208..191266 (+) 1059 Protein_165 competence type IV pilus assembly protein ComGB -
  MSA_RS01125 (MSA_2360) comGF 191248..191703 (+) 456 WP_016480233.1 competence type IV pilus minor pilin ComGF -
  MSA_RS01130 (MSA_2370) comGG 191681..192052 (+) 372 WP_016480234.1 competence type IV pilus minor pilin ComGG -
  MSA_RS01135 (MSA_2380) comYH 192167..193141 (+) 975 WP_001008571.1 class I SAM-dependent methyltransferase Machinery gene
  MSA_RS01140 (MSA_2390) - 193173..194366 (+) 1194 WP_000047534.1 acetate kinase -
  MSA_RS01145 (MSA_2400) - 194494..194701 (+) 208 Protein_170 helix-turn-helix transcriptional regulator -
  MSA_RS11940 (MSA_2410) - 194760..194891 (+) 132 WP_079269272.1 hypothetical protein -

Sequence

Protein


Download         Length: 323 a.a.        Molecular weight: 36742.22 Da        Isoelectric Point: 6.9761

>NTDB_id=59099 MSA_RS01115 WP_016480231.1 189343..190314(+) (comYA) [Streptococcus agalactiae ILRI005]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELHMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide


Download         Length: 972 bp        

>NTDB_id=59099 MSA_RS01115 WP_016480231.1 189343..190314(+) (comYA) [Streptococcus agalactiae ILRI005]
ATGGTTCAATCATTAGCAAAGCACGTCATTCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCCATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTAATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTTGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.489

96.285

0.659
  comYA Streptococcus mutans UA140

68.489

96.285

0.659
  comYA Streptococcus gordonii str. Challis substr. CH1

63.323

98.762

0.625
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

63.023

96.285

0.607
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.058

96.285

0.598
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.058

96.285

0.598
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.058

96.285

0.598
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.058

96.285

0.598
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

61.613

95.975

0.591
  comGA Lactococcus lactis subsp. cremoris KW2

50.311

99.69

0.502

Multiple sequence alignment