Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   I872_RS09910 Genome accession   NC_021175
Coordinates   2008966..2010222 (-) Length   418 a.a.
NCBI ID   WP_015605952.1    Uniprot ID   A0A512AE51
Organism   Streptococcus cristatus AS 1.3089     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2003966..2015222
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS09875 - 2004660..2004970 (-) 311 Protein_1942 DUF1292 domain-containing protein -
  I872_RS09880 (I872_09905) ruvX 2004991..2005410 (-) 420 WP_015605947.1 Holliday junction resolvase RuvX -
  I872_RS09885 (I872_09910) - 2005410..2005676 (-) 267 WP_005592119.1 IreB family regulatory phosphoprotein -
  I872_RS09890 (I872_09915) - 2005844..2006401 (-) 558 WP_015605948.1 SP0191 family lipoprotein -
  I872_RS09895 (I872_09920) - 2006445..2007011 (-) 567 WP_015605949.1 SP0191 family lipoprotein -
  I872_RS09900 (I872_09925) spx 2007276..2007674 (-) 399 WP_015605950.1 transcriptional regulator Spx -
  I872_RS09905 (I872_09930) recA 2007760..2008908 (-) 1149 WP_015605951.1 recombinase RecA Machinery gene
  I872_RS09910 (I872_09935) cinA 2008966..2010222 (-) 1257 WP_015605952.1 competence/damage-inducible protein A Machinery gene
  I872_RS09915 (I872_09940) - 2010492..2010902 (+) 411 WP_041826926.1 helix-turn-helix domain-containing protein -
  I872_RS09920 (I872_09945) - 2010946..2011503 (-) 558 WP_015605954.1 GNAT family N-acetyltransferase -
  I872_RS09925 (I872_09950) - 2011575..2012234 (-) 660 WP_015605955.1 type II CAAX prenyl endopeptidase Rce1 family protein -
  I872_RS09930 (I872_09955) - 2012239..2012793 (-) 555 WP_015605956.1 DNA-3-methyladenine glycosylase I -
  I872_RS09935 (I872_09960) ruvA 2012803..2013393 (-) 591 WP_015605957.1 Holliday junction branch migration protein RuvA -
  I872_RS09940 (I872_09965) - 2013563..2014069 (+) 507 WP_015605958.1 helix-turn-helix domain-containing protein -
  I872_RS09945 (I872_09970) - 2014053..2014628 (+) 576 WP_015605959.1 RDD family protein -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 44805.97 Da        Isoelectric Point: 4.6542

>NTDB_id=58489 I872_RS09910 WP_015605952.1 2008966..2010222(-) (cinA) [Streptococcus cristatus AS 1.3089]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLASLGVDVYFQTAVGDNENRLLSVLEIAKERSDLIILTGGLGPTEDDLTKQT
LAKFVGRDLSFDPAAVEKLDRFFASRPDYARTPNNERQAQLVTGSTPLPNATGLAVGGLLEADGVTYVVLPGPPSELKPM
VNNELVPLLSTGQKLYSRVLRFFGIGESQLVTILAEMIEQQSDPTIAPYAKTGEVTLRLSTKALSQAEADAKFEAVEKSI
LAHQTFEGQPLSEIFYGYGDDNSLAQVAFDLLKSQGKTISAAESLTAGLFQATLADFAGASSIFSGGFVTYSMEEKSRML
DIPLEELEQHGVVSAFTAGKMAEQARKLTRSDLAVSLTGVAGPDSLEGHPAGTVFIGLASESGTEMIEVNIAGRSRRDVR
KIAVMHAFNLVRKTLLKN

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=58489 I872_RS09910 WP_015605952.1 2008966..2010222(-) (cinA) [Streptococcus cristatus AS 1.3089]
ATGAAAGCAGAAATTATTGCTGTGGGCACAGAGATTCTGACAGGTCAGATTGTCAATACCAATGCCCAGTTTTTATCTGA
AAAGCTAGCTAGTCTAGGAGTTGATGTCTATTTTCAGACGGCAGTGGGGGACAATGAAAATCGTCTTCTCTCTGTCCTAG
AAATTGCCAAAGAGCGCAGTGATTTAATTATCCTGACAGGGGGATTGGGACCAACAGAGGATGATTTGACCAAGCAGACC
TTGGCTAAATTTGTCGGTCGAGATTTGAGCTTCGATCCAGCGGCTGTGGAAAAGTTAGATCGTTTTTTTGCTAGCCGACC
GGACTATGCCCGAACGCCCAACAATGAACGTCAGGCCCAGCTGGTGACAGGCTCGACTCCGCTACCAAATGCGACTGGCT
TAGCTGTTGGCGGTTTATTAGAAGCCGACGGAGTGACCTATGTGGTCCTGCCTGGCCCACCTAGCGAGCTCAAACCTATG
GTCAATAACGAGCTGGTTCCCCTCCTATCCACAGGACAGAAATTGTATTCACGGGTGCTCCGCTTCTTCGGTATTGGCGA
GAGTCAGCTGGTAACTATTTTGGCCGAGATGATTGAGCAACAAAGCGATCCGACCATTGCACCTTATGCAAAGACGGGCG
AAGTGACCTTGCGATTGTCCACCAAGGCTTTGAGTCAGGCAGAAGCTGATGCCAAGTTTGAGGCTGTGGAAAAGTCTATT
TTGGCGCATCAGACTTTTGAGGGACAGCCTTTGTCTGAGATTTTCTACGGTTATGGAGACGACAATTCGCTTGCTCAAGT
GGCCTTTGACTTGCTCAAGAGTCAAGGAAAGACGATTTCGGCGGCGGAGAGTCTGACAGCAGGACTCTTTCAGGCCACCT
TGGCTGATTTTGCTGGAGCTTCTTCCATTTTTTCAGGTGGCTTTGTCACCTACAGCATGGAGGAAAAGAGCCGGATGCTG
GATATTCCATTGGAAGAGCTGGAGCAGCACGGCGTTGTTTCTGCTTTTACGGCTGGGAAAATGGCAGAGCAGGCTAGAAA
GCTGACTCGGAGTGACTTGGCTGTCAGTCTGACAGGCGTGGCAGGACCAGATTCGCTGGAAGGCCATCCAGCTGGGACAG
TTTTTATTGGCCTAGCGAGTGAATCAGGAACGGAAATGATTGAGGTCAATATTGCTGGTCGCAGCCGACGTGATGTGCGG
AAAATTGCTGTCATGCACGCCTTCAACCTCGTACGAAAAACTTTATTAAAGAACTGA

Domains

Predicted by InterproScan.

Competence-damaged protein (CinA)

(262-415)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A512AE51

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mitis SK321

77.512

100

0.775
  cinA Streptococcus mitis NCTC 12261

77.033

100

0.77
  cinA Streptococcus pneumoniae TIGR4

77.033

100

0.77
  cinA Streptococcus pneumoniae Rx1

77.033

100

0.77
  cinA Streptococcus pneumoniae R6

77.033

100

0.77
  cinA Streptococcus pneumoniae D39

76.794

100

0.768
  cinA Streptococcus mutans UA159

74.702

100

0.749
  cinA Streptococcus suis isolate S10

54.087

99.522

0.538
  cinA Bacillus subtilis subsp. subtilis str. 168

47.608

100

0.476

Multiple sequence alignment