Detailed information NTG0582239

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: VB13_RS04385
• Genome accession: NZ_CP077685
• Coordinates: 875431..876267 (+)
• Length: 278 a.a.
• NCBI ID: WP_012560715.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M49 591
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 870431..881267

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
VB13_RS04355 (VB13_04505)	-	870913..871353 (+)	441	WP_009880949.1	hypothetical protein	-
VB13_RS04360 (VB13_04510)	-	871403..872314 (-)	912	WP_002984631.1	diacylglycerol kinase family protein	-
VB13_RS04365 (VB13_04515)	-	872431..873081 (-)	651	WP_002984629.1	hemolysin III family protein	-
VB13_RS04370 (VB13_04520)	-	873078..873518 (-)	441	WP_002984627.1	DUF1836 domain-containing protein	-
VB13_RS04375 (VB13_04525)	ylqF	873737..874585 (+)	849	WP_002984625.1	ribosome biogenesis GTPase YlqF	-
VB13_RS04380 (VB13_04530)	-	874575..875366 (+)	792	WP_011888871.1	ribonuclease HII	-
VB13_RS04385 (VB13_04535)	dprA	875431..876267 (+)	837	WP_012560715.1	DNA-processing protein DprA	Machinery gene
VB13_RS04390 (VB13_04540)	topA	876374..878503 (+)	2130	WP_009880713.1	type I DNA topoisomerase	-
VB13_RS04395	-	878579..879436 (-)	858	Protein_824	LysR family transcriptional regulator	-
VB13_RS04400 (VB13_04550)	-	879476..880042 (+)	567	Protein_825	PTS sugar transporter subunit IIC	-
VB13_RS04405 (VB13_04555)	-	880057..881049 (+)	993	WP_009880715.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30987.06 Da
• Isoelectric Point: 9.5635

>NTDB_id=582239 VB13_RS04385 WP_012560715.1 875431..876267(+) (dprA) [Streptococcus pyogenes strain M49 591]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRKLQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=582239 VB13_RS04385 WP_012560715.1 875431..876267(+) (dprA) [Streptococcus pyogenes strain M49 591]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGAAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367
dprA	Acinetobacter baumannii strain A118	38.202	96.043	0.367
dprA	Acinetobacter baumannii D1279779	37.828	96.043	0.363