Detailed information    

insolico Bioinformatically predicted

Overview

Name   sepM   Type   Regulator
Locus tag   SPN994038_RS09390 Genome accession   NC_021026
Coordinates   1745940..1746977 (-) Length   345 a.a.
NCBI ID   WP_000727274.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN994038     
Function   processing of CSP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1740940..1751977
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN994038_RS09370 (SPN994038_17150) - 1741679..1743010 (-) 1332 WP_000390039.1 hemolysin family protein -
  SPN994038_RS09375 (SPN994038_17160) endA 1743301..1744125 (-) 825 WP_001036786.1 DNA-entry nuclease EndA Machinery gene
  SPN994038_RS09380 (SPN994038_17170) - 1744164..1744352 (-) 189 WP_001036519.1 DNA-directed RNA polymerase subunit beta -
  SPN994038_RS09385 (SPN994038_17180) murA 1744345..1745628 (-) 1284 WP_000358034.1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase -
  SPN994038_RS11890 (SPN994038_17190) - 1745652..1745882 (-) 231 WP_001809307.1 DUF1146 family protein -
  SPN994038_RS09390 (SPN994038_17200) sepM 1745940..1746977 (-) 1038 WP_000727274.1 SepM family pheromone-processing serine protease Regulator
  SPN994038_RS09395 (SPN994038_17210) coaD 1746961..1747449 (-) 489 WP_001280736.1 pantetheine-phosphate adenylyltransferase -
  SPN994038_RS09400 (SPN994038_17220) rsmD 1747439..1747978 (-) 540 WP_000706951.1 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD -
  SPN994038_RS09405 (SPN994038_17230) asnA 1748043..1749035 (-) 993 WP_000747993.1 aspartate--ammonia ligase -
  SPN994038_RS09415 (SPN994038_17240) - 1749147..1749830 (-) 684 WP_001016917.1 Bax inhibitor-1/YccA family protein -
  SPN994038_RS09420 (SPN994038_17250) - 1749886..1750626 (-) 741 WP_000152680.1 TrmH family RNA methyltransferase -
  SPN994038_RS09425 (SPN994038_17260) - 1750660..1750938 (+) 279 WP_001174613.1 acylphosphatase -
  SPN994038_RS09430 (SPN994038_17270) yidC 1751016..1751942 (+) 927 WP_000835949.1 membrane protein insertase YidC -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 37566.57 Da        Isoelectric Point: 4.8549

>NTDB_id=58119 SPN994038_RS09390 WP_000727274.1 1745940..1746977(-) (sepM) [Streptococcus pneumoniae SPN994038]
MKKKIRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDTEDKEAGAYQFVTVGVQHATLAHMIYAWLTPFT
DIRSAQETTGGSSDVEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFEGILNISDTVTAVNDQTF
DSSKDLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPISFSTAGIGGPSAGLMFSL
AIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVASARAGAAIFFAPDNPVSEEEQKAHPDVKNNYQTALEAAK
TIKTDMKIVPVKTLQDAIDYLKNNP

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=58119 SPN994038_RS09390 WP_000727274.1 1745940..1746977(-) (sepM) [Streptococcus pneumoniae SPN994038]
ATGAAAAAAAAGATTAGATGGCCCTTATACGTCATTGCGGCCTTGATTGTGACTTTCTTGGCATTTGTAGTGCCCTTGCC
TTATTATATAGAGGTTCCAGGTGGTTCGGAAGATATTCGCCAAGTCCTTAAAGTAAATGACACAGAAGATAAGGAAGCTG
GTGCCTATCAATTCGTTACGGTTGGTGTTCAACATGCCACTTTAGCTCATATGATTTATGCTTGGTTGACACCTTTTACA
GATATTCGTAGTGCTCAGGAGACTACAGGTGGTTCTTCCGATGTTGAATTTATGCGAATCAATCAATTCTACATGCAAAC
ATCACAAAATATGGCCAAGTATCAAGGACTAAAAACAGCTGGTAAGGATATCGAACTCAAGTACTTTGGAGTTTATGTTT
TGAATGTGACGGATAATTCAACCTTTGAAGGGATTCTCAATATCTCTGATACGGTCACAGCAGTCAATGATCAGACCTTT
GATAGTTCCAAAGACTTGATTGATTACGTCAGTTCTCAAAAATTAGGGGACTCCGTCAAGGTCACCTATGAAGAGGATGG
GCAAACCAAGTCTGCAGAAGGAAAGATTATCACCTTGGAAAATGGAAAAAATGGGATTGGAATCGGCTTGATTGATCGTA
CAGAGGTAATCAGCAATGTCCCAATTAGCTTTTCAACAGCTGGTATTGGCGGCCCAAGTGCTGGTCTCATGTTTAGTCTA
GCTATCTATACTCAAATAGCTCACCCAGATCTTCGTAATGGTCGTATTGTTGCCGGTACAGGTACCATTGACCGCGATGG
TAATGTGGGAGACATTGGAGGTATTGATAAGAAGGTTGTAGCTTCGGCTAGGGCAGGTGCTGCTATTTTCTTTGCTCCTG
ATAACCCTGTTAGCGAAGAAGAACAAAAGGCGCATCCGGACGTGAAAAACAACTACCAAACAGCCCTAGAAGCGGCTAAA
ACAATCAAGACGGATATGAAAATCGTGCCCGTTAAAACCCTACAAGATGCGATTGATTACTTGAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(130-193)

Lon protease (S16) C-terminal proteolytic domain (Lon_C)

(231-298)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sepM Streptococcus mutans UA159

59.064

99.13

0.586

Multiple sequence alignment