Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   SPN032672_RS06145 Genome accession   NC_021003
Coordinates   1150785..1152041 (+) Length   418 a.a.
NCBI ID   WP_000642703.1    Uniprot ID   -
Organism   Streptococcus pneumoniae SPN032672     
Function   facilitate localization of RecA (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1145785..1157041
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN032672_RS06110 - 1145804..1146100 (-) 297 WP_000911559.1 lactococcin 972 family bacteriocin -
  SPN032672_RS06115 - 1146415..1146585 (-) 171 WP_000742180.1 PhrA family quorum-sensing system peptide -
  SPN032672_RS06120 - 1146867..1147637 (+) 771 WP_225415938.1 helix-turn-helix domain-containing protein -
  SPN032672_RS06125 comM 1148020..1148640 (+) 621 WP_000839908.1 hypothetical protein Regulator
  SPN032672_RS06130 tsaE 1148726..1149169 (+) 444 WP_000288232.1 tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE -
  SPN032672_RS06135 - 1149159..1149677 (+) 519 WP_000455537.1 GNAT family N-acetyltransferase -
  SPN032672_RS06140 brpA 1149685..1150701 (+) 1017 WP_000239285.1 biofilm formation/cell division transcriptional regulator BrpA -
  SPN032672_RS06145 cinA 1150785..1152041 (+) 1257 WP_000642703.1 competence/damage-inducible protein A Machinery gene
  SPN032672_RS06150 recA 1152096..1153262 (+) 1167 WP_001085462.1 recombinase RecA Machinery gene
  SPN032672_RS12860 - 1153590..1154404 (-) 815 Protein_1133 IS5-like element IS1515 family transposase -
  SPN032672_RS06165 - 1154460..1155812 (+) 1353 WP_000364180.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45046.49 Da        Isoelectric Point: 4.6027

>NTDB_id=57885 SPN032672_RS06145 WP_000642703.1 1150785..1152041(+) (cinA) [Streptococcus pneumoniae SPN032672]
MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGDNEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQT
LAKFLGKALVFDPQAQEKLDIFFALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
VLNLLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQVDPTLAPYAKTGEVTLRLSTKASSQEEANQALDILENQI
LDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQGKTIAAAESLTAGLFQATVANFSGISSIFKGGFVTYSLEEKSRML
DIPAKNLEEHGVVSEFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQDQGTEVIKVNIGGRSRADVR
HIAVMHAFNLVRKALLSD

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=57885 SPN032672_RS06145 WP_000642703.1 1150785..1152041(+) (cinA) [Streptococcus pneumoniae SPN032672]
ATGAAAGCAGAAATCATTGCTGTTGGAACAGAGATTTTGACAGGACAGATTGTCAACACCAATGCCCAGTTTTTGTCGGA
AAAACTAGCTGAGATTGGGGTAGATGTATATTTTCAGACGGCTGTAGGAGACAATGAAGTTCGTCTCTTGTCTTTGCTTG
AGATTGCCAGTCAACGTAGCAGTCTGGTGATTTTGACAGGCGGTTTGGGGCCAACTGAGGACGACCTAACCAAACAAACC
CTAGCTAAATTTTTAGGGAAAGCATTAGTCTTTGATCCTCAGGCTCAGGAGAAGTTGGATATCTTTTTTGCCCTGCGACC
AGACTATGCCCGAACACCGAATAACGAAAGACAAGCTCAAATTGTAGAAGGAGCGATTCCACTGCCAAACGAAACAGGAC
TGGCTGTTGGAGGAAAATTAGAAGTAGACGGAGTGACCTATGTCGTCCTTCCAGGTCCGCCAAGTGAATTGAAACCCATG
GTCTTAAACCTACTTCTACCCAAGTTGATGACAGGGAGCAAGCTGTATTCCCGAGTTCTTCGTTTCTTTGGGATTGGCGA
GAGCCAGCTGGTTACGATTTTGGCTGATTTAATTGATAATCAGGTCGATCCTACCTTGGCCCCTTATGCCAAGACAGGAG
AAGTCACTCTACGTCTGTCAACAAAGGCTAGCAGTCAAGAAGAGGCGAATCAAGCGCTGGATATCTTGGAAAATCAAATC
TTGGACTGCCAGACTTTCGAAGGAATTTCTTTACGAGACTTTTGCTATGGTTATGGGGAAGAAACTAGTTTAGCCAGCAT
TGTGGTAGAAGAACTGAAAAGGCAAGGGAAAACCATCGCGGCTGCAGAGAGTTTGACGGCAGGTCTTTTCCAAGCTACCG
TGGCGAATTTTTCTGGAATTTCAAGTATATTTAAGGGTGGTTTTGTGACCTATAGCTTGGAGGAAAAATCAAGGATGTTG
GATATTCCTGCCAAGAATTTGGAAGAACATGGTGTGGTGTCTGAATTTACAGCTCAGAAGATGGCTGAGCAGGCACGAAG
CAAGACCCAGTCTGATTTTGGAATTAGTTTGACTGGAGTGGCAGGACCAGATAGCCTAGAAGGACACCCAGTTGGGACAG
TCTTCATAGGCTTGGCGCAAGATCAAGGAACTGAGGTTATCAAGGTTAATATTGGAGGCAGAAGCCGAGCAGATGTACGT
CACATTGCGGTTATGCATGCCTTTAACCTAGTTCGCAAGGCTTTATTAAGTGACTAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-169)

Damage-inducible protein CinA KH domain (CinA_KH)

(177-240)

Competence-damaged protein (CinA)

(262-414)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus pneumoniae TIGR4

99.043

100

0.99
  cinA Streptococcus pneumoniae Rx1

98.804

100

0.988
  cinA Streptococcus pneumoniae R6

98.804

100

0.988
  cinA Streptococcus pneumoniae D39

98.565

100

0.986
  cinA Streptococcus mitis SK321

93.541

100

0.935
  cinA Streptococcus mitis NCTC 12261

93.301

100

0.933
  cinA Streptococcus mutans UA159

71.053

100

0.711
  cinA Streptococcus suis isolate S10

55.048

99.522

0.548
  cinA Bacillus subtilis subsp. subtilis str. 168

45.694

100

0.457

Multiple sequence alignment