Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KQ224_RS06320 Genome accession   NZ_CP076721
Coordinates   1230082..1231263 (-) Length   393 a.a.
NCBI ID   WP_216806243.1    Uniprot ID   -
Organism   Streptococcus parasuis strain H35     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 1225082..1236263
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ224_RS06285 (KQ224_06285) comX/sigX 1225663..1226133 (-) 471 WP_024392830.1 sigma-70 family RNA polymerase sigma factor Regulator
  KQ224_RS06290 (KQ224_06290) - 1226314..1226862 (-) 549 WP_172036462.1 nucleotidyltransferase family protein -
  KQ224_RS06295 (KQ224_06295) - 1227138..1227458 (-) 321 WP_024392832.1 DUF1292 domain-containing protein -
  KQ224_RS06300 (KQ224_06300) ruvX 1227470..1227889 (-) 420 WP_130554426.1 Holliday junction resolvase RuvX -
  KQ224_RS06305 (KQ224_06305) - 1227889..1228155 (-) 267 WP_130554425.1 IreB family regulatory phosphoprotein -
  KQ224_RS06310 (KQ224_06310) spx 1228265..1228663 (-) 399 WP_024392835.1 transcriptional regulator Spx -
  KQ224_RS06315 (KQ224_06315) recA 1228876..1230030 (-) 1155 WP_174846500.1 recombinase RecA Machinery gene
  KQ224_RS06320 (KQ224_06320) cinA 1230082..1231263 (-) 1182 WP_216806243.1 competence/damage-inducible protein A Machinery gene
  KQ224_RS06325 (KQ224_06325) - 1231300..1231869 (-) 570 WP_171989012.1 DNA-3-methyladenine glycosylase I -
  KQ224_RS06330 (KQ224_06330) ruvA 1232489..1233079 (-) 591 WP_216806244.1 Holliday junction branch migration protein RuvA -
  KQ224_RS06335 (KQ224_06335) mutL 1233325..1235262 (-) 1938 WP_216806245.1 DNA mismatch repair endonuclease MutL -

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 42684.61 Da        Isoelectric Point: 4.4569

>NTDB_id=577584 KQ224_RS06320 WP_216806243.1 1230082..1231263(-) (cinA) [Streptococcus parasuis strain H35]
MKAELIAVGTEILTGQIVNTNAQFLSEKCAELGIDVYFHTAVGDNEQRLLSVLEIASKRSDLVILCGGLGPTEDDLTKQT
LATFLQKELVADELAMAKLDRFFASRPGRVRTPNNERQAQIVEGSQALQNPAGLAVGGMIEQDGVTYIVLPGPPSELKAM
FSESLLPFLTQSQQQLYSRVLRFFGIGESQLVTVLGDLIDKQTDPTLAPYAKVGEVTLRLSTKADSQEEANVRLNQLEEE
ILQRDHLRVFFYAYGDDNSLVKTVATLLEEKKQSLGILENGTGGLLQAELSLALAGQPYYSGGKIIGQLGTESGGLSEEA
SRIREELQADLGLVVSVAVKPESTVDNVLAKVYLALASTSGISKKEVDLGGYSWQYLRQLACLQALDFVRNTL

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=577584 KQ224_RS06320 WP_216806243.1 1230082..1231263(-) (cinA) [Streptococcus parasuis strain H35]
ATGAAAGCAGAATTAATTGCTGTTGGAACAGAAATATTGACAGGTCAAATTGTGAATACGAATGCTCAATTCTTGTCAGA
AAAATGTGCAGAGCTAGGTATCGATGTATACTTCCACACTGCTGTAGGTGATAATGAACAGCGACTATTGTCTGTACTTG
AAATTGCAAGTAAACGAAGTGATCTGGTCATTTTATGTGGTGGTTTAGGTCCTACTGAAGACGACTTGACTAAGCAAACT
TTAGCGACATTTTTGCAAAAAGAGTTGGTTGCTGACGAACTAGCGATGGCAAAATTAGACCGTTTTTTTGCCAGTCGACC
AGGTCGTGTTCGCACACCTAATAATGAGCGTCAAGCACAGATTGTGGAGGGAAGTCAGGCGCTACAGAACCCAGCTGGTT
TAGCTGTAGGTGGTATGATTGAGCAAGATGGTGTGACCTATATTGTTTTGCCTGGCCCACCAAGTGAACTCAAGGCCATG
TTTTCTGAGAGTCTGTTACCTTTTTTGACTCAATCTCAGCAACAACTTTACTCGCGTGTCCTACGCTTTTTTGGAATAGG
TGAAAGCCAGTTGGTGACTGTTTTAGGGGATTTGATTGACAAGCAGACAGACCCGACTCTTGCGCCTTATGCAAAAGTTG
GAGAGGTGACGCTTCGTTTATCTACGAAGGCAGATAGCCAGGAAGAAGCGAACGTTCGTTTGAATCAGTTGGAAGAAGAG
ATATTGCAACGTGACCATTTGAGAGTTTTTTTCTATGCATATGGGGATGACAATAGTTTGGTTAAAACCGTAGCGACTCT
TTTAGAGGAAAAGAAACAATCTTTGGGCATCCTAGAGAATGGAACAGGTGGTTTATTACAAGCAGAATTGAGTCTGGCTT
TGGCTGGTCAGCCGTATTATAGTGGAGGAAAAATCATCGGTCAGCTAGGGACAGAATCGGGCGGGCTATCAGAAGAAGCA
AGTCGCATTCGGGAGGAACTACAAGCTGATTTAGGGCTAGTTGTGTCGGTGGCAGTCAAACCAGAATCAACAGTAGACAA
CGTACTTGCTAAAGTATATCTAGCCTTGGCCAGTACCTCGGGTATTTCCAAAAAAGAGGTAGATTTAGGAGGTTATTCAT
GGCAATACCTTCGTCAACTTGCTTGTTTACAGGCGTTAGATTTTGTACGAAACACTTTGTGA

Domains

Predicted by InterproScan.

Damage-inducible protein CinA KH domain (CinA_KH)

(178-244)

Probable molybdopterin binding domain (MoCF_biosynth)

(5-170)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus suis isolate S10

87.023

100

0.87
  cinA Streptococcus mitis SK321

55.529

100

0.588
  cinA Streptococcus mitis NCTC 12261

55.288

100

0.585
  cinA Streptococcus pneumoniae TIGR4

54.808

100

0.58
  cinA Streptococcus pneumoniae Rx1

54.808

100

0.58
  cinA Streptococcus pneumoniae R6

54.808

100

0.58
  cinA Streptococcus mutans UA159

55.231

100

0.578
  cinA Streptococcus pneumoniae D39

54.567

100

0.578
  cinA Bacillus subtilis subsp. subtilis str. 168

47.231

78.117

0.369