Detailed information    

insolico Bioinformatically predicted

Overview

Name   cinA   Type   Machinery gene
Locus tag   KPU55_RS00235 Genome accession   NZ_CP076493
Coordinates   48216..49460 (+) Length   414 a.a.
NCBI ID   WP_002365395.1    Uniprot ID   A0A855UKS7
Organism   Enterococcus faecalis strain UAMS_EL54     
Function   require for competence (predicted from homology)   
Unclear

Genomic Context

Location: 43216..54460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPU55_RS00210 (KPU55_00205) - 44200..44991 (-) 792 WP_010706768.1 hypothetical protein -
  KPU55_RS00215 (KPU55_00210) - 45155..45538 (+) 384 WP_002365398.1 YccF domain-containing protein -
  KPU55_RS00220 (KPU55_00215) - 45627..46052 (+) 426 WP_002383201.1 Rrf2 family transcriptional regulator -
  KPU55_RS00225 (KPU55_00220) - 46111..46740 (+) 630 WP_002365397.1 NAD(P)-dependent oxidoreductase -
  KPU55_RS00230 (KPU55_00225) - 46819..48024 (-) 1206 WP_002367468.1 hypothetical protein -
  KPU55_RS00235 (KPU55_00230) cinA 48216..49460 (+) 1245 WP_002365395.1 competence/damage-inducible protein A Machinery gene
  KPU55_RS00240 (KPU55_00235) recA 49574..50620 (+) 1047 WP_002354860.1 recombinase RecA Machinery gene
  KPU55_RS00245 (KPU55_00240) rny 51017..52573 (+) 1557 WP_002354863.1 ribonuclease Y -
  KPU55_RS00250 (KPU55_00245) - 52733..53530 (+) 798 WP_002354864.1 TIGR00282 family metallophosphoesterase -
  KPU55_RS00255 (KPU55_00250) - 53604..53990 (+) 387 WP_002359008.1 YlbF family regulator -

Sequence

Protein


Download         Length: 414 a.a.        Molecular weight: 45193.29 Da        Isoelectric Point: 4.6698

>NTDB_id=575742 KPU55_RS00235 WP_002365395.1 48216..49460(+) (cinA) [Enterococcus faecalis strain UAMS_EL54]
MKAEIIAVGTELLLGQVVNTNATFLSEELAALGIDVYYQTVVGDNGGRLETLLTEAEQRSDLIVLCGGLGPTEDDLTKQV
VAQHLHKSLVEDQEGLNRLHQFFQQSKRPMTENNLRQVLAIEGGQVLQNPTGLAVGSFVTEGTTSYLLLPGPPNELIPMF
QQAARPLLIDAFPQEEQLISRVLRFYGIGESQLVTEIQSLIAHQTNPTIAPYAKPNEVTLRLTVKTKDLVAGEELLTATE
EKVLAKVGDYFYGYGDDNSLAKVTVDLLLQNGQTVTAAESLTAGLFQSTLGEIAGASKIFKGGFVTYSQETKENFLGISH
ELLEEHGTVSEACAKEMAEKARQLAKSNYGLSFTGVAGDPLEGQPTGTVWIGLAEEGQPTVAECFHFNRDRNYIRQSAVM
RGLDLLRRRIINKK

Nucleotide


Download         Length: 1245 bp        

>NTDB_id=575742 KPU55_RS00235 WP_002365395.1 48216..49460(+) (cinA) [Enterococcus faecalis strain UAMS_EL54]
ATGAAAGCAGAGATCATTGCAGTCGGAACAGAGTTATTACTGGGACAAGTAGTGAATACCAACGCCACCTTTTTATCAGA
AGAGTTAGCTGCGCTAGGCATCGATGTTTACTATCAGACCGTTGTTGGTGATAACGGCGGCCGCTTAGAAACGCTACTAA
CAGAAGCAGAACAAAGAAGTGATTTAATTGTCCTTTGTGGAGGGCTAGGACCTACAGAAGACGATTTAACCAAGCAAGTT
GTCGCACAACATCTCCATAAATCATTAGTAGAAGATCAAGAAGGATTGAACCGCTTGCACCAGTTTTTCCAACAGTCTAA
GCGGCCAATGACGGAAAATAATCTACGACAAGTGTTAGCCATCGAAGGTGGACAAGTTCTTCAAAACCCGACAGGATTAG
CGGTTGGTTCTTTTGTAACAGAAGGCACAACAAGCTATTTGCTCTTACCAGGACCACCCAATGAATTAATTCCGATGTTC
CAACAAGCGGCACGACCTTTATTGATTGATGCGTTTCCACAAGAAGAACAATTGATTTCGAGAGTCTTGCGTTTTTATGG
CATTGGTGAATCCCAGCTGGTGACCGAGATTCAATCGTTGATTGCGCACCAAACGAATCCAACCATTGCGCCTTATGCTA
AGCCTAATGAAGTGACACTTCGTTTAACAGTTAAAACAAAAGACTTAGTAGCTGGCGAAGAATTATTAACAGCGACGGAA
GAAAAGGTTTTAGCTAAAGTGGGAGACTATTTTTATGGGTATGGGGATGACAATAGTTTAGCCAAGGTAACAGTGGATTT
GTTATTACAAAACGGACAAACCGTTACGGCTGCTGAGAGCCTCACCGCTGGCCTATTCCAAAGTACACTGGGGGAAATTG
CGGGTGCTTCGAAGATTTTTAAGGGAGGCTTCGTGACGTATTCGCAAGAAACAAAAGAGAACTTTTTAGGAATTTCTCAT
GAACTTTTAGAAGAACATGGCACGGTAAGTGAAGCGTGTGCCAAAGAAATGGCAGAGAAAGCGCGTCAGTTAGCTAAATC
TAACTATGGTTTATCATTTACTGGGGTCGCTGGTGACCCACTCGAAGGTCAACCGACAGGCACTGTTTGGATTGGGCTGG
CGGAAGAAGGCCAACCAACCGTTGCAGAATGTTTCCATTTTAACCGTGACCGAAATTATATTAGACAGAGTGCGGTTATG
CGAGGATTAGATCTTTTGCGGCGCCGAATCATTAATAAAAAATAA

Domains

Predicted by InterproScan.

Probable molybdopterin binding domain (MoCF_biosynth)

(5-168)

Competence-damaged protein (CinA)

(258-409)

Damage-inducible protein CinA KH domain (CinA_KH)

(180-253)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A855UKS7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  cinA Streptococcus mutans UA159

52.632

100

0.531
  cinA Streptococcus mitis SK321

51.773

100

0.529
  cinA Streptococcus mitis NCTC 12261

51.537

100

0.527
  cinA Streptococcus pneumoniae TIGR4

50.827

100

0.519
  cinA Streptococcus pneumoniae D39

50.591

100

0.517
  cinA Streptococcus pneumoniae R6

50.355

100

0.514
  cinA Streptococcus pneumoniae Rx1

50.355

100

0.514
  cinA Bacillus subtilis subsp. subtilis str. 168

48.522

98.068

0.476
  cinA Streptococcus suis isolate S10

44.039

99.275

0.437